Gene - combatTB X

PE_PGRS35

Type: protein_coding
Name: PE_PGRS35
Locus Name: Rv1983
Product: PE-PGRS family protein PE_PGRS35
Functional Category: Pe/ppe
Location: 2226244..2227920 (+ strand)
Gene Length: 1676 bp
Nucleotides: TGTCATTTCTGGTCGTGGTTCCCGAGTTCTTGACGTCCGCGGCAGCGGATGTGGAGAACATAGGTTCCACACTGCGCGCGGCGAATGCCGCGGCTGCCGCCTCGACCACCGCGCTTGCGGCCGCTGGCGCTGATGAGGTATCGGCGGCGGTGGCAGCGCTGTTTGCCAGGTTCGGTCAGGAATATCAAGCGGTCAGCGCGCAGGCGAGCGCTTTCCATCAACAGTTCGTGCAGACGCTGAACTCGGCGTCAGGATCGTATGCGGCCGCGGAGGCCACCATCGCGTCACAGTTGCAGACCGCGCAGCACGATCTGCTGGGCGCGGTCAATGCACCAACCGAAACGTTGTTGGGGCGTCCGCTAATCGGCGACGGAGCACCCGGGACGGCAACGAGTCCGAATGGCGGGGCGGGTGGGCTGCTGTACGGCAACGGCGGCAACGGTTATTCCGCGACGGCGTCGGGGGTCGGCGGCGGGGCCGGCGGTTCCGCGGGGTTGATCGGCAATGGCGGCGCCGGGGGAGCCGGCGGACCCAACGCCCCCGGGGGAGCCGGCGGCAACGGTGGCTGGCTGCTCGGCAACGGCGGGATCGGCGGGCCCGGGGGCGCGTCGAGCATCCCCGGCATGAGTGGTGGAGCCGGCGGAACCGGCGGTGCCGCAGGACTTTTGGGCTGGGGAGCGAACGGCGGAGCCGGCGGCCTCGGTGATGGAGTCGGTGTCGATCGTGGCACGGGCGGCGCCGGAGGCCGCGGCGGCCTGTTGTATGGCGGATACGGCGTCAGTGGGCCAGGCGGCGACGGCAGAACCGTCCCGCTGGAGATAATTCATGTCACAGAGCCGACGGTACATGCCAACGTCAACGGCGGACCGACGTCAACCATTCTGGTCGACACCGGATCCGCTGGTCTTGTTGTCTCGCCTGAGGATGTCGGGGGAATCCTGGGAGTGCTTCACATGGGCCTCCCAACCGGATTGAGCATCAGCGGTTACAGCGGGGGGCTGTACTACATCTTCGCCACGTATACCACGACGGTGGACTTCGGGAATGGCATCGTCACCGCGCCGACCGCCGTTAATGTCGTCCTCTTGTCCATCCCAACGTCCCCCTTCGCCATTTCGACCTACTTCAGCGCCTTGCTGGCCGATCCGACAACAACTCCGTTCGAAGCCTATTTCGGTGCCGTCGGCGTGGACGGCGTTCTGGGAGTTGGGCCCAATGCGGTGGGACCAGGCCCCAGCATTCCGACGATGGCGTTACCGGGTGACCTCAACCAGGGAGTGCTCATCGACGCACCCGCAGGTGAGCTCGTGTTCGGTCCCAACCCGCTACCTGCGCCCAACGTCGAGGTCGTCGGATCGCCGATCACCACCCTGTACGTAAAGATCGATGGTGGGACTCCCATACCCGTCCCCTCGATCATCGATTCCGGTGGGGTAACGGGAACCATCCCGTCATATGTCATCGGATCCGGAACCCTGCCGGCGAACACAAACATTGAGGTCTACACCAGCCCCGGCGGTGATCGGCTCTACGCGTTCAACACAAACGATTACCGCCCGACCGTCATTTCATCCGGCCTGATGAATACCGGGTTCTTGCCCTTCAGATTCCAGCCGGTGTACATCGACTACAGCCCCAGCGGTATAGGGACAACAGTCTTTGATCATCCGGCGTGA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Mycobacterial PE family, PGRS subfamily

GO

plasma membrane GO:0005886 cellular_component
integral component of membrane GO:0016021 cellular_component

InterPro

UniProt: P9WIF1
GenBank: Rv1983
EnsemblBacteria: Rv1983
Mycobrowser: Rv1983

Summary

Name: Uncharacterized PE-PGRS family protein PE_PGRS35
Family: Mycobacterial PE family, PGRS subfamily
Protein Sequence: MSFLVVVPEFLTSAAADVENIGSTLRAANAAAAASTTALAAAGADEVSAAVAALFARFGQEYQAVSAQASAFHQQFVQTLNSASGSYAAAEATIASQLQTAQHDLLGAVNAPTETLLGRPLIGDGAPGTATSPNGGAGGLLYGNGGNGYSATASGVGGGAGGSAGLIGNGGAGGAGGPNAPGGAGGNGGWLLGNGGIGGPGGASSIPGMSGGAGGTGGAAGLLGWGANGGAGGLGDGVGVDRGTGGAGGRGGLLYGGYGVSGPGGDGRTVPLEIIHVTEPTVHANVNGGPTSTILVDTGSAGLVVSPEDVGGILGVLHMGLPTGLSISGYSGGLYYIFATYTTTVDFGNGIVTAPTAVNVVLLSIPTSPFAISTYFSALLADPTTTPFEAYFGAVGVDGVLGVGPNAVGPGPSIPTMALPGDLNQGVLIDAPAGELVFGPNPLPAPNVEVVGSPITTLYVKIDGGTPIPVPSIIDSGGVTGTIPSYVIGSGTLPANTNIEVYTSPGGDRLYAFNTNDYRPTVISSGLMNTGFLPFRFQPVYIDYSPSGIGTTVFDHPA
Mass: 53,738 Da
Length: 558 Aa

Rv1983 doesn't seem to be a targeted by any drug.

Rv1983 doesn't seem to be involved in any pathway.

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.