Gene - combatTB X

Rv1999c

Type: protein_coding
Name: Rv1999c
Locus Name: Rv1999c
Product: Probable conserved integral membrane protein
Functional Category: Cell wall and cell processes
Location: 2243816..2245138 (- strand)
Gene Length: 1322 bp
Nucleotides: ATGAGACGCCCGCTAGACCCACGCGATATTCCAGATGAGCTGCGGCGACGGCTGGGGCTCTTGGATGCGGTGGTGATCGGGCTTGGGTCCATGATCGGTGCCGGAATCTTTGCCGCCCTGGCCCCGGCCGCGTACGCGGCCGGTTCTGGGTTGTTGCTCGGGTTGGCAGTGGCCGCGGTGGTGGCCTACTGCAATGCGATCTCGTCGGCGCGGCTGGCCGCGCGCTACCCGGCCTCGGGGGGCACCTATGTGTATGGCCGGATGCGGCTGGGCGACTTCTGGGGATACCTGGCGGGCTGGGGCTTTGTGGTCGGCAAGACGGCATCGTGTGCGGCGATGGCGTTGACGGTCGGCTTCTATGTGTGGCCCGCGCAAGCGCACGCGGTGGCCGTCGCCGTGGTGGTGGCACTGACCGCGGTGAACTACGCCGGGATACAGAAGTCCGCCTGGCTCACCCGGTCGATCGTCGCCGTGGTGTTGGTGGTCTTGACCGCAGTCGTGGTCGCCGCCTATGGCTCCGGCGCTGCGGACCCGGCGCGACTCGATATCGGTGTAGATGCACACGTCTGGGGGATGCTGCAGGCGGCCGGCCTGCTGTTTTTCGCGTTCGCCGGCTATGCCCGCATCGCCACGCTGGGGGAGGAGGTCCGCGACCCGGCCCGCACGATCCCACGCGCCATCCCGCTGGCGCTGGGCATCACCCTGGCGGTGTATGCCCTGGTCGCCGTGGCCGTGATCGCTGTGTTGGGTCCGCAGCGGCTCGCGCGGGCCGCCGCCCCGTTGTCGGAGGCCATGCGGGTCGCGGGGGTGAACTGGCTGATTCCCGTCGTGCAGATAGGGGCCGCGGTGGCCGCATTGGGCTCGCTACTGGCCTTGATTCTCGGGGTCTCCCGCACCACCTTGGCGATGGCACGCGACCGGCACCTACCGCGCTGGCTGGCCGCCGTGCACCCTAGGTTCAAGGTGCCCTTTCGTGCCGAACTGGTGGTTGGCGCGGTGGTGGCGGCGCTGGCGGCGACAGCGGATATCCGTGGTGCGATCGGCTTTTCGTCCTTCGGTGTGCTGGTCTACTACGCGATCGCCAACGCCTCCGCCTTGACTCTGGGGCTCGACGAGGGCCGGCCCCGCCGCCTGATTCCGCTGGTGGGACTGATCGGCTGCGTAGTCCTGGCGTTCGCGCTGCCACTCTCCTCGGTGGCCGCCGGGGCCGCGGTGCTCGGTGTCGGTGTGGCGGCATACGGTGTGCGCCGCATCATCACTCGTCGAGCACGACAGACTGATTCTGGTGATACCCAACGAAGTGGTCATCCGTCCGCAACCTA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Probable amino-acid or metabolite transport protein. {ECO:0000250}.

Family

Amino acid-polyamine-organocation (APC) superfamily

GO

transmembrane transporter activity GO:0022857 molecular_function
plasma membrane GO:0005886 cellular_component
integral component of membrane GO:0016021 cellular_component

InterPro

IPR002293

UniProt: P9WQM3
GenBank: Rv1999c
EnsemblBacteria: Rv1999c
Mycobrowser: Rv1999c

Summary

Name: Uncharacterized transporter Rv1999c
Family: Amino acid-polyamine-organocation (APC) superfamily
Protein Sequence: MRRPLDPRDIPDELRRRLGLLDAVVIGLGSMIGAGIFAALAPAAYAAGSGLLLGLAVAAVVAYCNAISSARLAARYPASGGTYVYGRMRLGDFWGYLAGWGFVVGKTASCAAMALTVGFYVWPAQAHAVAVAVVVALTAVNYAGIQKSAWLTRSIVAVVLVVLTAVVVAAYGSGAADPARLDIGVDAHVWGMLQAAGLLFFAFAGYARIATLGEEVRDPARTIPRAIPLALGITLAVYALVAVAVIAVLGPQRLARAAAPLSEAMRVAGVNWLIPVVQIGAAVAALGSLLALILGVSRTTLAMARDRHLPRWLAAVHPRFKVPFRAELVVGAVVAALAATADIRGAIGFSSFGVLVYYAIANASALTLGLDEGRPRRLIPLVGLIGCVVLAFALPLSSVAAGAAVLGVGVAAYGVRRIITRRARQTDSGDTQRSGHPSAT
Mass: 45,267 Da
Length: 440 Aa

Rv1999c doesn't seem to be a targeted by any drug.

Rv1999c doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.