Gene - combatTB X

Rv2000

Type: protein_coding
Name: Rv2000
Locus Name: Rv2000
Product: Unknown protein
Functional Category: Conserved hypotheticals
Location: 2245209..2246822 (+ strand)
Gene Length: 1613 bp
Nucleotides: TGCGTCCAGGGTTTGTGGGTTTGGGGTTTGGTCAGTGGCCGGTCTACGTTGTTCGCTGGCCTAAACTCCACCTGACGCCGCGGCAGCGAAAGCGTGTCTTGCATCGGCGACGATTGCTCACCGATCGCCCGATTTCGTTGTCACAAATTCCAATCCGCACAGGAGGGCCCATGAACGACCCGTGGCCCAGGCCAACGCAAGGGCCGGCGAAAACCATCGAAACCGACTACCTGGTGATAGGTGCCGGAGCGATGGGAATGGCATTCACGGATACCCTCATCACCGAGTCCGGTGCGCGCGTCGTCATGATCGACCGCGCATGTCAACCTGGTGGACATTGGACCACCGCCTACCCGTTCGTGCGGCTACACCAGCCATCGGCCTATTACGGCGTCAACTCAAGGGCACTAGGCAACAACACCATTGACCTCGTCGGTTGGAACCAGGGACTGAACGAACTGGCACCAGTCGGCGAGATATGCGCCTACTTCGATGCTGTATTGCAGCAGCAACTGCTCCCCACCGGGCGGGTTGACTACTTCCCGATGAGCGAATACCTGGGCGACGGCCGGTTCCGGACACTGGCAGGCACCGAATACGTCGTCACCGTCAATCGGCGCATCGTCGATGCCACCTACCTGCGTGCCGTCGTACCGTCGATGCGGCCGGCGCCGTACTCGGTTGCACCCGGCGTCGACTGCGTCGCTCCAAACGAACTGCCCAAACTCGGCACCCGGGATCGCTACGTGGTCGTCGGTGCCGGCAAGACCGGCATGGACGTCTGCCTATGGTTGCTCCGAAACGACGTCTGCCCTGACAAGCTGACCTGGATCATGCCGCGTGATTCCTGGCTGATCGACCGAGCGACGCTGCAGCCCGGGCCCACATTCGTCAGGCAGTTCAGGGAAAGCTACGGTGCGACTCTCGAGGCCATCGGGGCCGCGACCTCGACCGACGATCTGTTCGACCGACTAGAGACCGCCGGAACCCTGCTGCGCATCGACCCCTCGGTGCGTCCGAGCATGTATCGCTGCGCCACTGTGTCGCACCTCGAACTCGAGCAGCTGCGCCGTATCCGCGACATCGTCAGGATGGGCCACGTCCAACGCATCGAGCCCACCACGATAGTGCTCGACGGCGGATCGGTTCCCGCCACACCCACGGCCCTCTATATTGACTGCACCGCCGATGGAGCACCACAACGTCCAGCCAAGCCGGTTTTCGACGCAGACCACCTAACCCTGCAAGCCGTGCGCGGATGCCAACAGGTGTTCAGCGCCGCGTTTATCGCGCACGTCGAATTCGCCTACGAGGACGACGCGGTGAAAAACGAACTCTGTACCCCGATTCCACACCCGGACTGCGATCTGGACTGGATGCGTCTGATGCACTCCGATCTAGGCAACTTTCAGCGCTGGTTAAACGACCCCGATCTGACGGACTGGCTGAGCTCGGCGCGGTTGAACTTGCTCGCCGACCTGCTGCCGCCGTTGTCTCACAAGCCGCGGGTGCGCGAGCGGGTGGTGTCGATGTTCCAAAAGAGGTTGGGCACCGCCGGCGACCAGCTAGCGAAGCTGCTCGACGCCGCCACCGCAACAACCGAACAACGCTAA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Unknown

GO

cell wall GO:0005618 cellular_component
cytosol GO:0005829 cellular_component
plasma membrane GO:0005886 cellular_component

InterPro

IPR036188

UniProt: P9WLN7
GenBank: Rv2000
EnsemblBacteria: Rv2000
Mycobrowser: Rv2000

Summary

Name: Uncharacterized protein Rv2000
Family: Unknown
Protein Sequence: MRPGFVGLGFGQWPVYVVRWPKLHLTPRQRKRVLHRRRLLTDRPISLSQIPIRTGGPMNDPWPRPTQGPAKTIETDYLVIGAGAMGMAFTDTLITESGARVVMIDRACQPGGHWTTAYPFVRLHQPSAYYGVNSRALGNNTIDLVGWNQGLNELAPVGEICAYFDAVLQQQLLPTGRVDYFPMSEYLGDGRFRTLAGTEYVVTVNRRIVDATYLRAVVPSMRPAPYSVAPGVDCVAPNELPKLGTRDRYVVVGAGKTGMDVCLWLLRNDVCPDKLTWIMPRDSWLIDRATLQPGPTFVRQFRESYGATLEAIGAATSTDDLFDRLETAGTLLRIDPSVRPSMYRCATVSHLELEQLRRIRDIVRMGHVQRIEPTTIVLDGGSVPATPTALYIDCTADGAPQRPAKPVFDADHLTLQAVRGCQQVFSAAFIAHVEFAYEDDAVKNELCTPIPHPDCDLDWMRLMHSDLGNFQRWLNDPDLTDWLSSARLNLLADLLPPLSHKPRVRERVVSMFQKRLGTAGDQLAKLLDAATATTEQR
Mass: 59,895 Da
Length: 537 Aa

Rv2000 doesn't seem to be a targeted by any drug.

Rv2000 doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.