Rv2025c
- Type
- protein_coding
- Name
- Rv2025c
- Locus Name
-
Rv2025c
- Product
-
Conserved membrane protein
- Functional Category
-
Cell wall and cell processes
- Location
- 2270750..2271748 (- strand)
- Gene Length
- 998 bp
- Nucleotides
-
ATGACCCACGACCACGCTCATTCACGAGGTGTGCCGGCGATGATCAAGGAGATCTTCGCGCCGCACTCCCACGACGCCGCCGACAGCGTCGACGACACCCTGGAATCCACTGCGGCAGGGATCCGTACGGTCAAGATCAGCTTGTTGGTTCTCGGGTTGACCGCGCTCATCCAGATTGTGATCGTGGTGATGTCGGGGTCGGTTGCGCTGGCCGCCGACACCATCCACAACTTCGCTGATGCGTTGACCGCGGTGCCGTTGTGGATCGCGTTCGCGTTGGGCGCCAAGCCCGCCACTCGCCGATATACCTACGGATTCGGTCGCGTCGAGGACCTGGCCGGGTCGTTCGTGGTCGCGATGATCACGATGTCGGCCATCATCGCCGGTTACGAAGCCATCGCCCGCCTGATCCACCCGCAGCAGATCGAGCATGTCGGCTGGGTCGCCCTGGCCGGGCTGGTCGGATTCATCGGCAACGAGTGGGTTGCCCTCTACCGCATCAGGGTTGGGCACCGCATCGGCTCGGCCGCCCTGATCGCCGACGGACTACACGCTCGAACCGACGGATTCACCTCGCTGGCCGTGCTGTGCTCGGCCGGCGGTGTCGCACTTGGGTTCCCACTGGCCGACCCCATCGTCGGCCTGCTCATCACGGCGGCGATTCTGGCCGTGCTACGAACTGCCGCGCGAGATGTGTTCCGCCGCCTGCTCGACGGCGTCGACCCAGCGATGGTCGATGCCGCCGAACAAGCCCTGGCGGCCCGGCCCGGCGTGCAGGCGGTACGCAGCGTGCGGATGCGCTGGATCGGACACCGCTTGCACGCCGATGCCGAACTCGACGTCGACCCCGCCCTGGACCTCGCGCAAGCTCACCGCATCGCCCACGACGCCGAACACGAACTCACCCACACCGTTCCCAAGCTGACCACCGCCCTCATCCACGCCTATCCGGCTGAACATGGCTCGTCGATCCCAGATCGTGGCCGCACCGTAGAGTG
- Drug Resistance
- Mutations
- Function
- Unknown
- Family
-
Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
- GO
-
- zinc efflux active transmembrane transporter activity GO:0015341 molecular_function
- cation transmembrane transporter activity GO:0008324 molecular_function
- cadmium ion transmembrane transporter activity GO:0015086 molecular_function
- plasma membrane GO:0005886 cellular_component
- ferrous iron transmembrane transporter activity GO:0015093 molecular_function
- cellular cadmium ion homeostasis GO:0006876 biological_process
- cellular iron ion homeostasis GO:0006879 biological_process
- cellular zinc ion homeostasis GO:0006882 biological_process
- integral component of membrane GO:0016021 cellular_component
- membrane GO:0016020 cellular_component
- InterPro
Summary
- Name
- Probable cation efflux system protein Rv2025c
- Family
- Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
- Protein Sequence
-
MTHDHAHSRGVPAMIKEIFAPHSHDAADSVDDTLESTAAGIRTVKISLLVLGLTALIQIVIVVMSGSVALAADTIHNFADALTAVPLWIAFALGAKPATRRYTYGFGRVEDLAGSFVVAMITMSAIIAGYEAIARLIHPQQIEHVGWVALAGLVGFIGNEWVALYRIRVGHRIGSAALIADGLHARTDGFTSLAVLCSAGGVALGFPLADPIVGLLITAAILAVLRTAARDVFRRLLDGVDPAMVDAAEQALAARPGVQAVRSVRMRWIGHRLHADAELDVDPALDLAQAHRIAHDAEHELTHTVPKLTTALIHAYPAEHGSSIPDRGRTVE
- Mass
- 35,207 Da
- Length
- 332 Aa
Rv2025c doesn't seem to be a targeted by any drug.
Rv2025c doesn't seem to be involved in any pathway.
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Mycobacterial cells have dual nickel-cobalt sensors: sequence relationships and metal sites of metal-responsive repressors are not congruent.
- J Biol Chem. 2007 Nov 2;282(44):32298-310. doi: 10.1074/jbc.M703451200. Epub 2007 Aug 28.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.