Gene - combatTB X

Type: protein_coding
Name: Rv2148c
Locus Name: Rv2148c
Product: Conserved protein
Functional Category: Conserved hypotheticals
Location: 2406840..2407616 (- strand)
Gene Length: 776 bp
Nucleotides: ATGGCGGCGGATCTTTCGGCGTATCCAGACCGCGAATCGGAATTGACGCATGCGTTGGCGGCAATGCGATCGCGACTTGCGGCGGCCGCGGAGGCGGCGGGTCGCAATGTCGGCGAAATTGAACTTCTACCGATTACCAAATTCTTTCCAGCAACCGATGTTGCGATTTTGTTTCGATTGGGTTGTCGGTCCGTTGGCGAATCGCGCGAACAGGAAGCTTCAGCCAAGATGGCCGAACTTAATCGGTTGTTGGCGGCTGCCGAGTTGGGTCACTCGGGGGGTGTGCACTGGCACATGGTGGGCCGGATTCAACGCAACAAAGCCGGGTCGCTGGCTCGCTGGGCGCACACCGCTCACTCGGTGGACAGCTCGCGGTTGGTGACCGCGCTGGATCGGGCGGTTGTTGCGGCGCTGGCCGAACACCGTCGTGGCGAGCGGCTGCGGGTTTACGTCCAGGTCAGCCTCGACGGTGACGGATCCCGGGGCGGCGTCGACAGCACGACGCCCGGCGCCGTAGACCGGATTTGCGCGCAGGTGCAGGAGTCAGAGGGCCTCGAACTGGTCGGGTTGATGGGCATTCCGCCGCTGGATTGGGACCCGGACGAGGCCTTTGACCGGCTGCAATCGGAGCACAACCGGGTGCGTGCGATGTTCCCGCACGCGATCGGTCTGTCGGCGGGCATGTCCAACGACCTTGAAGTCGCCGTCAAACATGGTTCGACCTGTGTGCGTGTCGGTACCGCGCTATTGGGTCCGCGGCGGTTACGGTCACCGTG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. {ECO:0000255|HAMAP-Rule:MF_02087}.

Family

Pyridoxal phosphate-binding protein YggS/PROSC family

GO

InterPro

Summary

Name: Pyridoxal phosphate homeostasis protein (PLP homeostasis protein)
Family: Pyridoxal phosphate-binding protein YggS/PROSC family
Protein Sequence: MAADLSAYPDRESELTHALAAMRSRLAAAAEAAGRNVGEIELLPITKFFPATDVAILFRLGCRSVGESREQEASAKMAELNRLLAAAELGHSGGVHWHMVGRIQRNKAGSLARWAHTAHSVDSSRLVTALDRAVVAALAEHRRGERLRVYVQVSLDGDGSRGGVDSTTPGAVDRICAQVQESEGLELVGLMGIPPLDWDPDEAFDRLQSEHNRVRAMFPHAIGLSAGMSNDLEVAVKHGSTCVRVGTALLGPRRLRSP
Mass: 27,693 Da
Length: 258 Aa

Rv2148c doesn't seem to be a targeted by any drug.

Rv2148c doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.