Rv2216
- Type
- protein_coding
- Name
- Rv2216
- Locus Name
-
Rv2216
- Product
-
Conserved protein
- Functional Category
-
Conserved hypotheticals
- Location
- 2483626..2484531 (+ strand)
- Gene Length
- 905 bp
- Nucleotides
-
TGGCCAACGCCGTTGTCGCGATCGCGGGTTCGTCTGGCTTGATCGGCTCTGCCCTGACCGCGGCGCTGCGCGCGGCCGACCACACGGTGCTGCGGATCGTGCGCCGGGCACCTGCGAATTCCGAAGAACTGCACTGGAATCCCGAAAGCGGCGAATTCGATCCGCACGCGCTCACCGATGTCGACGCCGTGGTCAACCTCTGCGGCGTCAACATCGCCCAGCGTCGGTGGTCGGGGGCTTTCAAACAGAGCCTGCGCGACAGCCGGATCACACCCACCGAGGTGCTATCCGCCGCAGTCGCCGACGCCGGCGTCGCTACCTTGATCAACGCCAGCGCGGTGGGCTACTACGGAAACACCAAGGACCGGGTGGTCGACGAAAACGACTCGGCGGGAACAGGTTTTCTGGCCCAGCTGTGCGTTGACTGGGAAACCGCCACGCGGCCGGCGCAGCAGAGCGGTGCCCGCGTGGTGCTGGCCCGGACCGGAGTGGTGCTGTCTCCGGCGGGGGGCATGCTGCGACGCATGCGGCCACTGTTTTCGGTGGGCCTGGGCGCGCGGCTGGGCAGCGGCCGGCAATATATGTCATGGATCAGCCTGGAGGACGAGGTGCGGGCGCTGCAGTTCGCTATCGCGCAGCCCAACCTGTCCGGCCCGGTGAACTTGACCGGGCCGGCCCCCGTTACCAACGCCGAATTCACCACCGCGTTTGGCCGCGCCGTCAACCGCCCTACCCCGCTGATGTTGCCTAGCGTCGCGGTACGCGCGGCGTTTGGTGAGTTCGCCGACGAGGGGTTGCTCATTGGTCAGCGCGCCATCCCCTCCGCGCTGGAGCGAGCCGGATTTCAGTTCCACCACAACACCATTGGCGAGGCGCTCGGCTACGCCACCACCCGGCCCGGCTAG
- Drug Resistance
- Mutations
- Function
- Unknown
- Family
-
NAD(P)-dependent epimerase/dehydratase family, SDR39U1 subfamily
- GO
-
- heme binding GO:0020037 molecular_function
- cholesterol 26-hydroxylase activity GO:0031073 molecular_function
- cell wall GO:0005618 cellular_component
- plasma membrane GO:0005886 cellular_component
- coenzyme binding GO:0050662 molecular_function
- cholest-4-en-3-one 26-monooxygenase activity GO:0036199 molecular_function
- cholesterol catabolic process GO:0006707 biological_process
- InterPro
Summary
- Name
- Epimerase family protein Rv2216
- Family
- NAD(P)-dependent epimerase/dehydratase family, SDR39U1 subfamily
- Protein Sequence
-
MANAVVAIAGSSGLIGSALTAALRAADHTVLRIVRRAPANSEELHWNPESGEFDPHALTDVDAVVNLCGVNIAQRRWSGAFKQSLRDSRITPTEVLSAAVADAGVATLINASAVGYYGNTKDRVVDENDSAGTGFLAQLCVDWETATRPAQQSGARVVLARTGVVLSPAGGMLRRMRPLFSVGLGARLGSGRQYMSWISLEDEVRALQFAIAQPNLSGPVNLTGPAPVTNAEFTTAFGRAVNRPTPLMLPSVAVRAAFGEFADEGLLIGQRAIPSALERAGFQFHHNTIGEALGYATTRPG
- Mass
- 31,672 Da
- Length
- 301 Aa
Rv2216 doesn't seem to be a targeted by any drug.
Rv2216 doesn't seem to be involved in any pathway.
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.