cobD
- Type
- protein_coding
- Name
- cobD
- Locus Name
-
Rv2236c
- Product
-
Probable cobalamin biosynthesis transmembrane protein CobD
- Functional Category
-
Intermediary metabolism and respiration
- Location
- 2508434..2509375 (- strand)
- Gene Length
- 941 bp
- Nucleotides
-
GTGTTTGCATCGACCTGGCAGACCAGGGCCGTCGGCGTGCTGATCGGCTGCCTGCTCGACGTCGTGTTCGGCGACCCCAAACGAGGTCATCCGGTGGCCCTGTTCGGTCGGGCGGCCGCCAAGCTGGAGCAGATCACCTACCGTGACGGCCGGGTCGCCGGTGCGGTACACGTCGGCCTGCTGGTCGGCGCGGTGGGCTTGCTCGGCGCGGCACTGCAGCGGCTACCCGGCAGGTCCTGGCCCGTGGCGGCCACCGCGACGGCCACCTGGGCAGCGCTGGGCGGAACTTCGCTGGCGCGCACCGGCCGCCAGATATCGGACCTGTTGGAGCGCGACGATGTCGAGGCGGCGCGACGGCTGCTGCCGTCGCTGTGCGGGCGTGACCCGGCCCAGCTGGGCGGCCCGGGCCTGACGCGTGCCGCGCTGGAGTCGGTGGCCGAAAACACCGCCGACGCCCAGGTGGTGCCGCTGCTGTGGGCGGCTTCGAGCGGCGTGCCTGCGGTGCTGGGATATCGTGCCATCAACACCCTGGACTCGATGATCGGCTACCGCTCGCCGCGTTATCTCCGATTCGGTTGGGCTGCAGCACGATTGGATGACTGGGCCAACTATGTTGGCGCACGGGCGACGGCGGTGCTGGTGGTGATCTGCGCGCCGGTGGTCGGTGGGTCGCCCCGCGGTGCGGTACGGGCCTGGCGGCGCGACGCCGCCCGCCATCCCAGCCCCAACGCCGGTGTCGTCGAGGCGGCGTTTGCTGGGGCGCTTGACGTGCGGCTGGGTGGGCCCACCCGGTACCACCATGAGTTGCAGATCCGGCCCACCTTGGGCGACGGCCGGTCGCCCAAGGTGGCCGATCTGCGCCGCGCCGTGGTGCTGTCGCGGGTGGTCCAGGCGGGGGCTGCGGTATTGGCCGTGATGTTGGTTTACCGCCGGCGGCCGTA
- Drug Resistance
- Mutations
- Function
- Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. {ECO:0000250}.
- Family
-
CobD/CbiB family
- GO
-
- cobalamin biosynthetic process GO:0009236 biological_process
- threonine-phosphate decarboxylase activity GO:0048472 molecular_function
- ATPase-coupled vitamin B12 transmembrane transporter activity GO:0015420 molecular_function
- extracellular region GO:0005576 cellular_component
- plasma membrane GO:0005886 cellular_component
- integral component of membrane GO:0016021 cellular_component
- InterPro
Summary
- Name
- Cobalamin biosynthesis protein CobD
- Family
- CobD/CbiB family
- Protein Sequence
-
MFASTWQTRAVGVLIGCLLDVVFGDPKRGHPVALFGRAAAKLEQITYRDGRVAGAVHVGLLVGAVGLLGAALQRLPGRSWPVAATATATWAALGGTSLARTGRQISDLLERDDVEAARRLLPSLCGRDPAQLGGPGLTRAALESVAENTADAQVVPLLWAASSGVPAVLGYRAINTLDSMIGYRSPRYLRFGWAAARLDDWANYVGARATAVLVVICAPVVGGSPRGAVRAWRRDAARHPSPNAGVVEAAFAGALDVRLGGPTRYHHELQIRPTLGDGRSPKVADLRRAVVLSRVVQAGAAVLAVMLVYRRRP
- Mass
- 32,976 Da
- Length
- 313 Aa
Rv2236c doesn't seem to be a targeted by any drug.
-
-
Porphyrin and chlorophyll metabolism mtu00860
mtu00860PATHWAY_MAP mtu00860 Porphyrin and chlorophyll metabolism
-
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.