Function

Catalyzes C-C bond formation between the carbons ortho to the phenolic hydroxyl of cyclo(L-tyr-L-tyr) (cYY) producing mycocyclosin. Can also use cyclo(L-Tyr-L-Phe) (cYF), cyclo(L-Tyr-L-Trp) (cYW) and cyclo(L-Tyr-L-3,4-dihydroxyphenylalanine) (cY-DOPA) as substrate. {ECO:0000269|PubMed:12237220, ECO:0000269|PubMed:19416919, ECO:0000269|Ref.2}.

Family

Cytochrome P450 family

GO

• cholesterol catabolic process GO:0006707 biological_process
• oxidoreductase activity GO:0016491 molecular_function
• cholest-4-en-3-one 26-monooxygenase activity GO:0036199 molecular_function
• oxidation-reduction process GO:0055114 biological_process
• carbon monoxide binding GO:0070025 molecular_function
• cytoplasm GO:0005737 cellular_component
• steroid hydroxylase activity GO:0008395 molecular_function
• iron ion binding GO:0005506 molecular_function
• heme binding GO:0020037 molecular_function
• cyclase activity GO:0009975 molecular_function
• oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated GO:0046996 molecular_function

InterPro

• IPR001128
• IPR002397
• IPR017972
• IPR036396

UniProt

P9WPP7

GenBank

Rv2276

EnsemblBacteria

Rv2276

Mycobrowser

Rv2276

Rv2276 doesn't seem to be a targeted by any drug.

Rv2276 doesn't seem to be involved in any pathway.