Rv2295
- Type
- protein_coding
- Name
- Rv2295
- Locus Name
-
Rv2295
- Product
-
Conserved hypothetical protein
- Functional Category
-
Conserved hypotheticals
- Location
- 2566772..2567410 (+ strand)
- Gene Length
- 638 bp
- Nucleotides
-
TGGACCAGTCGGCCAACCATGCGTGTCTGCCCACCCCGCTGGCGAGCACAACAGGGCGCGGGCAAGATCATGAGATGCCTGTCGAAGAGACCTCCACCCCCCAGAAGCTGCCCCAATTTCGTTATCACCCCGATCCCGTCGGCACCGGCTCGATAGTCGCCGACGAGGTGAGCTGCGTGAGCTGCGAGCAACGTCGGCCCTACACCTACACCGGCCCGGTGTATGCGGAGGAGGAGCTTAACGAGGCCATCTGTCCTTGGTGTATCGCAGATGGCAGTGCGGCGAGTCGCTTCGATGCCACGTTCACCGACGCCATGTGGGCGGTGCCCGACGACGTTCCAGAGGACGTGACCGAGGAAGTGCTGTGCCGAACACCCGGGTTCACGGGCTGGCTGCAGGAGGAATGGTTGCATCACTGCGGGGACGCCGCCGCCTTCCTTGGCCCGGTGGGCGCCAGCGAGGTGGCCGACCTCCCTGACGCCCTGGATGCGCTGCGCAATGAGTACCGCGGCTACGACTGGCCCGCCGACAAAATCGAGGAATTCATCCTGACGCTCGATCGAAACGGGCTGGCGACCGCCTACCTCTTCAGGTGCCTGAGCTGCGGCGTCCACTTGGCCTACGCCGATTTCGCTTAA
- Drug Resistance
- Mutations
- Function
- Probably plays a role in host phagosome maturation arrest (PubMed:20844580). {ECO:0000305|PubMed:20844580}.
- Family
-
UPF0167 family
- GO
-
- negative regulation by symbiont of host innate immune response GO:0052170 biological_process
- InterPro
Summary
- Name
- UPF0167 protein Rv2295
- Family
- UPF0167 family
- Protein Sequence
-
MPVEETSTPQKLPQFRYHPDPVGTGSIVADEVSCVSCEQRRPYTYTGPVYAEEELNEAICPWCIADGSAASRFDATFTDAMWAVPDDVPEDVTEEVLCRTPGFTGWLQEEWLHHCGDAAAFLGPVGASEVADLPDALDALRNEYRGYDWPADKIEEFILTLDRNGLATAYLFRCLSCGVHLAYADFA
- Mass
- 20,691 Da
- Length
- 187 Aa
Rv2295 doesn't seem to be a targeted by any drug.
Rv2295 doesn't seem to be involved in any pathway.
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- High content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling.
- PLoS Pathog. 2010 Sep 9;6(9):e1001100. doi: 10.1371/journal.ppat.1001100.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.