Gene - combatTB X

Rv2326c

Type: protein_coding
Name: Rv2326c
Locus Name: Rv2326c
Product: Possible transmembrane ATP-binding protein ABC transporter
Functional Category: Cell wall and cell processes
Location: 2597854..2599947 (- strand)
Gene Length: 2093 bp
Nucleotides: ATGTGCTGCGCCGTGTGCGGGCCTGAGCCTGGCAGAATCGGTGAAGTGACCCCGCTCGGCCCTTGCCCCGCGCAACATCGGGGCGGGCCGCTGCGGCCGAGTGAATTGGCGCAGGCGTCGGTGATGGCGGCGCTGTGCGCGGTGACCGCGATCATCTCCGTCGTCGTTCCGTTCGCGGCCGGTCTGGCGCTGTTGGGCACCGTGCCCACCGGCCTGCTGGCCTACCGCTACCGTCTCCGCGTGCTGGCGGCCGCGACGGTTGCGGCCGGGATGATCGCCTTCCTGATCGCGGGGCTGGGCGGTTTCATGGGGGTGGTCCACAGTGCCTACATCGGTGGGCTGACCGGAATCGTCAAACGCAGGGGCCGGGGCACCCCGACGGTGGTCGTCTCGTCGCTGATCGGCGGATTCGTGTTCGGCGCGGCGATGGTCGGGATGTTGGCCGCCATGGTCCGACTGCGGCATCTGATTTTCAAGGTCATGACCGCAAACGTGGACGGTATCGCCGCCACCTTGGCCCGGATGCACATGCAGGGGGCAGCCGCCGACGTCAAGCGGTATTTCGCCGAGGGACTGCAGTACTGGCCGTGGGTGCTGCTGGGCTATTTCAACATTGGGATCATGATCGTGTCGCTGATTGGGTGGTGGGCGTTGTCGCGCCTGCTGGAGCGGATGCGCGGAATCCCCGATGTACACAAACTTGACCCACCGCCAGGAGATGACGTGGACGCTCTGATCGGGCCGGTGCCGGTGCGGTTGGACAAGGTCCGCTTCCGTTACCCCCGCGCCGGCCAAGATGCGCTGCGGGAGGTCAGCCTCGACGTCCGGGCCGGCGAGCACCTAGCGATCATCGGGGCCAACGGATCAGGGAAGACCACCTTGATGCTGATACTGGCCGGCCGGGCACCGACGTCGGGCACCGTGGATCGTCCGGGCACGGTGGGTTTGGGAAAGCTGGGCGGCACCGCTGTCGTCTTGCAGCATCCGGAAAGCCAGGTCCTGGGCACCCGGGTTGCCGACGACGTGGTGTGGGGGCTGCCGCTGGGTACCACCGCTGACGTTGGCCGGTTGCTGAGCGAGGTCGGCTTGGAAGCGCTTGCCGAACGCGACACCGGAAGCCTGTCCGGTGGTGAGCTGCAGCGCCTGGCGCTGGCGGCAGCGCTGGCCCGGGAGCCGGCGATGCTCATCGCCGACGAGGTCACCACCATGGTTGACCAGCAGGGCAGGGACGCTTTGCTGGCCGTGCTGTCGGGTCTGACGCAGCGGCACCGGACCGCCTTGGTGCACATCACGCACTACGACAACGAAGCCGATTCCGCCGACCGCACGCTCAGCCTGAGCGATTCGCCGGATAACACCGATATGGTCCACACCGCCGCGATGCCGGCCCCGGTCATCGGGGTGGATCAGCCCCAGCACGCGCCGGCGCTCGAACTGGTGGGCGTCGGCCACGAATACGCTAGCGGCACCCCGTGGGCAAAGACCGCGTTGCGCGATATCAACTTCGTTGTTGAGCAGGGAGACGGGGTGCTGATCCACGGCGGCAATGGCTCGGGGAAGTCGACGCTGGCGTGGATCATGGCCGGGCTGACGATCCCCACGACCGGAGCCTGCCTACTTGACGGTCGGCCCACCCACGAGCAGGTCGGCGCGGTGGCGTTGTCTTTTCAGGCGGCCCGGCTGCAGCTGATGCGCAGCCGTGTAGACCTGGAAGTTGCTTCCGCAGCAGGTTTTTCGGCTAGCGAGCAGGACCGGGTGGCTGCGGCGCTGACTGTCGTTGGGTTGGACCCCGCGCTGGGCGCGCGACGAATCGACCAGCTCAGCGGGGGCCAGATGCGTCGGGTGGTGCTGGCCGGGCTGCTTGCGCGTGCACCCCGGGCGTTGATCCTCGATGAGCCGTTGGCGGGGTTGGACGCGGCCAGCCAGCGCGGCCTGCTGCGGCTGCTGGAAGACTTGCGTCGGGCGCGCGGCCTGACGGTGGTCGTAGTTTCGCACGACTTCGCGGGGATGGAGGAGCTTTGCCCGCGTACCCTGCATCTGCGCGACGGTGTGCTGGAATCGGCGGCGGCGTCGGAGGCGGGGGGAATGTCATG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

ABC transporter superfamily

GO

cell wall GO:0005618 cellular_component
ATP binding GO:0005524 molecular_function
integral component of plasma membrane GO:0005887 cellular_component
ATPase-coupled transmembrane transporter activity GO:0042626 molecular_function
ATP-binding cassette (ABC) transporter complex GO:0043190 cellular_component
plasma membrane GO:0005886 cellular_component

InterPro

UniProt: P9WQI7
GenBank: Rv2326c
EnsemblBacteria: Rv2326c
Mycobrowser: Rv2326c

Summary

Name: Uncharacterized ABC transporter ATP-binding protein Rv2326c
Family: ABC transporter superfamily
Protein Sequence: MCCAVCGPEPGRIGEVTPLGPCPAQHRGGPLRPSELAQASVMAALCAVTAIISVVVPFAAGLALLGTVPTGLLAYRYRLRVLAAATVAAGMIAFLIAGLGGFMGVVHSAYIGGLTGIVKRRGRGTPTVVVSSLIGGFVFGAAMVGMLAAMVRLRHLIFKVMTANVDGIAATLARMHMQGAAADVKRYFAEGLQYWPWVLLGYFNIGIMIVSLIGWWALSRLLERMRGIPDVHKLDPPPGDDVDALIGPVPVRLDKVRFRYPRAGQDALREVSLDVRAGEHLAIIGANGSGKTTLMLILAGRAPTSGTVDRPGTVGLGKLGGTAVVLQHPESQVLGTRVADDVVWGLPLGTTADVGRLLSEVGLEALAERDTGSLSGGELQRLALAAALAREPAMLIADEVTTMVDQQGRDALLAVLSGLTQRHRTALVHITHYDNEADSADRTLSLSDSPDNTDMVHTAAMPAPVIGVDQPQHAPALELVGVGHEYASGTPWAKTALRDINFVVEQGDGVLIHGGNGSGKSTLAWIMAGLTIPTTGACLLDGRPTHEQVGAVALSFQAARLQLMRSRVDLEVASAAGFSASEQDRVAAALTVVGLDPALGARRIDQLSGGQMRRVVLAGLLARAPRALILDEPLAGLDAASQRGLLRLLEDLRRARGLTVVVVSHDFAGMEELCPRTLHLRDGVLESAAASEAGGMS
Mass: 72,835 Da
Length: 697 Aa

Rv2326c doesn't seem to be a targeted by any drug.

ABC transporters mtu02010
mtu02010
Environmental Information Processing; Membrane transport

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.