Gene - combatTB X

narK1

Type: protein_coding
Name: narK1
Locus Name: Rv2329c
Product: Probable nitrite extrusion protein 1 NarK1 (nitrite facilitator 1)
Functional Category: Cell wall and cell processes
Location: 2601914..2603461 (- strand)
Gene Length: 1547 bp
Nucleotides: ATGGAACAGCACACGCTGCTGCAACGCGAGGAGTCGCCGCGCAGTCCCGCGGCCCCTTCGCTCAGGCGCCTGGGTGGCTCACGTCACATCACGCATTGGGATCCCGAGGATCTAGGAGCGTGGGAGGCAGGCAACAAGGGCATTGCCCGACGCAATCTGCTTTGGTCGGTCGTGACGGTTCACCTGGGTTACTCGGTGTGGACGCTCTGGCCGGTGCTGGAGTTGCTGATGCCCCAGGACGTCTACGGCTTTTCAACCAGTGACAAGTTTCTGCTCGGCACCATCGCGACGCTGTTTGGCGCGTTCCTGCGGATGCCCTACGCGTTGGCCAGCGCGATCTTTGGCGGTCGCAACTGGGCGACTTTTTCGGCAATCGTGTTGCTAATTCCGGCCATTGGCACAACGGTGTTGTTGACCCATCCGGGGCTACCGCTGTGGCCGTATCTGGTGTGTGCGGCCCTGACCGGCTTAGGCGGCGGCAACTTCGCGTCGTCAATGAGCAACGCCAATGCTTTCTATCCACATCGGCTCAAGGGTTCGGCGCTCGGAATTGCCGGTGGGGTAGGCAATCTCGGGGTGCCGGCGATCCAGCTAGTTGGGTTGTTGGCAATCGCCACTGTCGGTGAGCGGAAGCCTTACCTGGTCTGCGCACTGTATGTGGTTCTGGTGGCAATCGCGGTAATCGGAGTGTCGCTGTTCATGAACAATGTCGAACAGCACCGGGTGCAGGTGAACCGGCTTCGGCCGATCGTTTCCGCGGTTCTGTCGACCCGCGACACGTGGTTGCTCTCGCTGCTCTACCTCGGCACTTTCGGCTCATTCATCGGCTTCTCCTTCGTGTTTGGCCAGGTGTTGCAGACCAACTTCCTGGCGTGCGGACAAAGCCCGGCGCGCGCGACGCTGCATGCCGTCGAGTTGGCGTTTGTCGGGCCGTTGCTGGCGGCGGTGGCCCGGATTTACGGTGGCCGGCTGGCCGATCGAGTCGGTGGAAGCCGCTTGACCCTTATAGTCTTTGTGGCGATGACGCTCGCCGCTGGGCTGCTGATCAGTGCCAGCACCCTCGAAGGCCGACATGTCGGCCAGCATCGGGGCGCTACCATGGTCGGCTACTTCGTCTGCTTCGTCGCGTTGTTCGTCCTATCCGGGTTGGGCAACGGGTCTGTGTACAAGATGATTCCGACGATTTTTGAGGCGTGCAGCCGCTCCCTGGATCTCAGTGAAGCCGAACGCCGCGACTGGTCACGCATCATCTCAGGAGTAGTCATCGGGTTTGTGGCCGCCTTCGGCGCGCTCGGCGGGGTCGGAATCAATATGGCGCTGCGTGAGTCCTACCTCAGCACCGGCAGTGGGACCGATGCGTTCTGGATCTTCATGATGTGCTACGCCGCTGCCGCCGTTCTGACTTGGAAAGTGTACGACCGCCGAACGGTCACCGACATGGGGATGTTGCAGGCGGCCTTGGTGCGGCAGCCGGCATCGACGCCAGCCGAACTTATCGGTCCCAGAACTCAATCGGACCGATTCTCCGGGTGCAGCATCTCGGCGTA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Unknown

GO

nitrate transport GO:0015706 biological_process
nitrite transport GO:0015707 biological_process
integral component of plasma membrane GO:0005887 cellular_component
nitrite efflux transmembrane transporter activity GO:0015514 molecular_function
nitrate transmembrane transporter activity GO:0015112 molecular_function

InterPro

UniProt: P71883
GenBank: Rv2329c
EnsemblBacteria: Rv2329c
Mycobrowser: Rv2329c

Summary

Name: Probable nitrite extrusion protein 1 NarK1 (Nitrite facilitator 1)
Family: Unknown
Protein Sequence: MEQHTLLQREESPRSPAAPSLRRLGGSRHITHWDPEDLGAWEAGNKGIARRNLLWSVVTVHLGYSVWTLWPVLELLMPQDVYGFSTSDKFLLGTIATLFGAFLRMPYALASAIFGGRNWATFSAIVLLIPAIGTTVLLTHPGLPLWPYLVCAALTGLGGGNFASSMSNANAFYPHRLKGSALGIAGGVGNLGVPAIQLVGLLAIATVGERKPYLVCALYVVLVAIAVIGVSLFMNNVEQHRVQVNRLRPIVSAVLSTRDTWLLSLLYLGTFGSFIGFSFVFGQVLQTNFLACGQSPARATLHAVELAFVGPLLAAVARIYGGRLADRVGGSRLTLIVFVAMTLAAGLLISASTLEGRHVGQHRGATMVGYFVCFVALFVLSGLGNGSVYKMIPTIFEACSRSLDLSEAERRDWSRIISGVVIGFVAAFGALGGVGINMALRESYLSTGSGTDAFWIFMMCYAAAAVLTWKVYDRRTVTDMGMLQAALVRQPASTPAELIGPRTQSDRFSGCSISA
Mass: 55,136 Da
Length: 515 Aa

Rv2329c doesn't seem to be a targeted by any drug.

Nitrogen metabolism mtu00910
mtu00910
Metabolism; Energy metabolism

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.