Function

Global transcriptional regulator involved in zinc homeostasis. Represses the transcription of at least 32 genes, including genes involved in zinc homeostasis, by binding to promoter sequences that contain a conserved 26 bp palindrome, in the presence of zinc. {ECO:0000269|PubMed:17098899}.

Family

Fur family

GO

• transcription regulatory region DNA binding GO:0044212 molecular_function
• transcription regulatory region sequence-specific DNA binding GO:0000976 molecular_function
• regulation of secondary metabolite biosynthetic process GO:1900376 biological_process
• response to zinc ion GO:0010043 biological_process
• DNA-binding transcription factor activity GO:0003700 molecular_function
• DNA-binding transcription repressor activity GO:0001217 molecular_function
• protein-DNA complex GO:0032993 cellular_component
• cytosol GO:0005829 cellular_component
• protein homodimerization activity GO:0042803 molecular_function
• DNA binding GO:0003677 molecular_function
• positive regulation of transcription, DNA-templated GO:0045893 biological_process
• negative regulation of transcription, DNA-templated GO:0045892 biological_process
• plasma membrane GO:0005886 cellular_component
• zinc ion binding GO:0008270 molecular_function

InterPro

• IPR036390
• IPR036388
• IPR002481

UniProt

P9WN85

GenBank

Rv2359

EnsemblBacteria

Rv2359

Mycobrowser

Rv2359

Rv2359 doesn't seem to be a targeted by any drug.

Rv2359 doesn't seem to be involved in any pathway.