Gene - combatTB X

Type: protein_coding
Name: mbtH
Locus Name: Rv2377c
Product: Putative conserved protein MbtH
Functional Category: Lipid metabolism
Location: 2656215..2656430 (- strand)
Gene Length: 215 bp
Nucleotides: GTGAGCACCAATCCTTTCGATGACGACAACGGCGCATTCTTCGTGCTGGTCAACGACGAAGACCAGCACAGCCTGTGGCCGGTGTTCGCCGATATCCCGGCCGGCTGGCGCGTGGTGCACGGCGAAGCCAGCCGTGCCGCCTGCCTGGACTACGTGGAAAAGAACTGGACCGATCTGCGGCCGAAGAGCCTGCGTGACGCCATGGTCGAGGACTG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Could be involved in mycobactin synthesis. {ECO:0000250}.

Family

Unknown

GO

InterPro

Summary

Name: Protein MbtH
Family: Unknown
Protein Sequence: MSTNPFDDDNGAFFVLVNDEDQHSLWPVFADIPAGWRVVHGEASRAACLDYVEKNWTDLRPKSLRDAMVED
Mass: 8,082 Da
Length: 71 Aa

Rv2377c doesn't seem to be a targeted by any drug.

Monobactam biosynthesis mtu00261
mtu00261
Metabolism; Biosynthesis of other secondary metabolites

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.