Gene - combatTB X

Rv2456c

Type: protein_coding
Name: Rv2456c
Locus Name: Rv2456c
Product: Probable conserved integral membrane transport protein
Functional Category: Cell wall and cell processes
Location: 2756936..2758192 (- strand)
Gene Length: 1256 bp
Nucleotides: ATGTCGGGCACCGTTGTGGCAGTGCCGCCACGGGTGGCGCGTGCGCTGGACCTGCTGAATTTCTCGTTGGCTGATGTTCGCGACGGTCTGGGCCCCTATCTGTCGATATACCTCCTGTTGATCCACGATTGGGATCAAGCCTCGATCGGGTTCGTCATGGCGGTCGGCGGCATTGCGGCCATCGTGGCCCAGACGCCGATTGGCGCCCTGGTGGACCGGACCACGGCCAAGCGGGCGCTGGTCGTCGCCGGCGCGGTGCTGGTCACCGCCGCCGCAGTGGCGATGCCGCTGTTTGCGGGCTTGTATTCCATCTCGGTGCTGCAGGCCGTCACCGGGATCGCCAGCTCGGTTTTCGCTCCGGCGTTGGCGGCGATCACGTTGGGTGCTGTCGGTCCTCAGTTTTTCGCCAGACGGATTGGGCGTAACGAAGCGTTCAACCACGCCGGTAACGCGTCGGCGGCTGGGGCGACCGGCGCGCTGGCGTACTTCTTCGGGCCGGTGGTGGTGTTCTGGGTGCTGGCCGGCATGGCGTTGATCAGCGTGCTGGCGACACTGCGGATCCCGCCGGACGCGGTCGACCACGATTTAGCGCGTGGTATGGACCATGCGCCCGGCGAGCCGCATCCGCAGCCGTCGCGGTTCACCGTGTTGGCGCACAACCGCGAACTGGTGATCTTCGGGGCGGCGGTTGTCGCGTTCCACTTCGCCAACGCGGCGATGCTGCCGCTGGTCGGCGAGCTGTTGGCGTTGCACAATCGAGACGAAGGAACGGCGCTGATGTCGTCGTGCATCGTCGCGGCGCAGGTCGTGATGGTGCCGGTGGCGTATGTGGTCGGGACCAGGGCCGACGCGTGGGGGCGAAAGCCGATCTTTTTGGTGGGGTTCGCTGTCTTGACCGCTCGCGGGTTCCTCTACACGTTGTCGGATAACTCCTACTGGCTGGTGGGCGTGCAGTTGCTCGACGGTATCGGAGCCGGCATTTTCGGGGCGTTGTTTCCCCTTGTCGTACAGGACGTCACACACGGAACGGGACATTTCAATATCAGCCTCGGGGCGGTAACCACGGCAACGGGCATTGGTGCCGCGCTGTCTAATCTTGTTGCCGGCTGGATCGTGGTCGTCGCGGGCTATGACGCGGCATTCATGTCGCTGGGTGCGCTCGCCGGGGCCGGCTTCCTCCTGTACCTGGTCGCGATGCCGGAAACCGTGGATTCGGATGTCCGGGTGCGGTCGCGGCCAACCCTCGGGGGGAAGTG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Major facilitator superfamily

GO

transmembrane transport GO:0055085 biological_process
plasma membrane GO:0005886 cellular_component
integral component of membrane GO:0016021 cellular_component

InterPro

UniProt: P9WJX1
GenBank: Rv2456c
EnsemblBacteria: Rv2456c
Mycobrowser: Rv2456c

Summary

Name: Uncharacterized MFS-type transporter Rv2456c
Family: Major facilitator superfamily
Protein Sequence: MSGTVVAVPPRVARALDLLNFSLADVRDGLGPYLSIYLLLIHDWDQASIGFVMAVGGIAAIVAQTPIGALVDRTTAKRALVVAGAVLVTAAAVAMPLFAGLYSISVLQAVTGIASSVFAPALAAITLGAVGPQFFARRIGRNEAFNHAGNASAAGATGALAYFFGPVVVFWVLAGMALISVLATLRIPPDAVDHDLARGMDHAPGEPHPQPSRFTVLAHNRELVIFGAAVVAFHFANAAMLPLVGELLALHNRDEGTALMSSCIVAAQVVMVPVAYVVGTRADAWGRKPIFLVGFAVLTARGFLYTLSDNSYWLVGVQLLDGIGAGIFGALFPLVVQDVTHGTGHFNISLGAVTTATGIGAALSNLVAGWIVVVAGYDAAFMSLGALAGAGFLLYLVAMPETVDSDVRVRSRPTLGGK
Mass: 43,133 Da
Length: 418 Aa

Rv2456c doesn't seem to be a targeted by any drug.

Rv2456c doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.