echA14
- Type
- protein_coding
- Name
- echA14
- Locus Name
-
Rv2486
- Product
-
Probable enoyl-CoA hydratase EchA14 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase)
- Functional Category
-
Lipid metabolism
- Location
- 2794350..2795120 (+ strand)
- Gene Length
- 770 bp
- Nucleotides
-
TGGCCCAATACGACCCGGTCTTGCTCAGCGTCGACAAGCACGTTGCGCTCATCACGGTCAACGACCCGGACCGACGGAACGCCGTCACCGACGAGATGTCGGCGCAGTTGCGTGCGGCGATCCAACGCGCCGAAGGCGACCCCGACGTACACGCCGTAGTCGTGACCGGGGCGGGCAAGGCCTTCTGCGCCGGGGCCGACCTGAGTGCGCTGGGCGCCGGGGTCGGCGATCCAGCCGAGCCGAGATTGTTACGGCTCTACGACGGTTTCATGGCCGTCAGTAGTTGTAATCTGCCCACCATCGCCGCGGTCAACGGCGCGGCTGTGGGCGCCGGACTCAATCTGGCGTTGGCCGCCGATGTGCGCATCGCCGGACCGGCCGCATTGTTCGACGCCCGCTTCCAAAAGCTGGGACTGCATCCAGGTGGCGGCGCAACCTGGATGCTGCAGCGAGCGGTGGGTCCGCAGGTCGCCCGTGCGGCCTTATTGTTCGGCATGTGCTTCGACGCCGAATCCGCTGTGCGGCACGGCTTGGCGCTAATGGTTGCCGACGATCCCGTCACCGCGGCGCTGGAGCTGGCCGCCGGGCCCGCAGCCGCCCCGCGCGAGGTCGTGCTGGCGAGCAAAGCCACCATGCGCGCCACAGCCAGCCCCGGATCGCTGGACCTTGAGCAACACGAACTCGCCAAACGCTTAGAACTTGGGCCGCAGGCGAAATCGGTCCAGTCGCCCGAGTTCGCCGCTCGCTTGGCTGCCGCTCAACACAGGTAG
- Drug Resistance
- Mutations
- Function
- Could possibly oxidize fatty acids using specific components. {ECO:0000250}.
- Family
-
Enoyl-CoA hydratase/isomerase family
- GO
-
- isomerase activity GO:0016853 molecular_function
- enoyl-CoA hydratase activity GO:0004300 molecular_function
- fatty acid beta-oxidation GO:0006635 biological_process
- InterPro
- Name
- Probable enoyl-CoA hydratase echA14 (EC 4.2.1.17)
- Family
- Enoyl-CoA hydratase/isomerase family
- Protein Sequence
-
MAQYDPVLLSVDKHVALITVNDPDRRNAVTDEMSAQLRAAIQRAEGDPDVHAVVVTGAGKAFCAGADLSALGAGVGDPAEPRLLRLYDGFMAVSSCNLPTIAAVNGAAVGAGLNLALAADVRIAGPAALFDARFQKLGLHPGGGATWMLQRAVGPQVARAALLFGMCFDAESAVRHGLALMVADDPVTAALELAAGPAAAPREVVLASKATMRATASPGSLDLEQHELAKRLELGPQAKSVQSPEFAARLAAAQHR
- Mass
- 26,280 Da
- Length
- 256 Aa
Rv2486 doesn't seem to be a targeted by any drug.
-
-
Limonene and pinene degradation mtu00903
mtu00903PATHWAY_MAP mtu00903 Limonene and pinene degradation
-
-
-
Butanoate metabolism mtu00650
mtu00650PATHWAY_MAP mtu00650 Butanoate metabolism
-
-
-
Propanoate metabolism mtu00640
mtu00640PATHWAY_MAP mtu00640 Propanoate metabolism
-
-
-
Aminobenzoate degradation mtu00627
mtu00627PATHWAY_MAP mtu00627 Aminobenzoate degradation
-
-
-
beta-Alanine metabolism mtu00410
mtu00410PATHWAY_MAP mtu00410 beta-Alanine metabolism
-
-
-
Tryptophan metabolism mtu00380
mtu00380PATHWAY_MAP mtu00380 Tryptophan metabolism
-
-
-
Benzoate degradation mtu00362
mtu00362PATHWAY_MAP mtu00362 Benzoate degradation
-
-
-
Phenylalanine metabolism mtu00360
mtu00360PATHWAY_MAP mtu00360 Phenylalanine metabolism
-
-
-
Lysine degradation mtu00310
mtu00310PATHWAY_MAP mtu00310 Lysine degradation
-
-
-
Valine, leucine and isoleucine degradation mtu00280
mtu00280PATHWAY_MAP mtu00280 Valine, leucine and isoleucine degradation
-
-
-
Fatty acid degradation mtu00071
mtu00071PATHWAY_MAP mtu00071 Fatty acid degradation
-
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.