citE
- Type
- protein_coding
- Name
- citE
- Locus Name
-
Rv2498c
- Product
-
Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase)
- Functional Category
-
Intermediary metabolism and respiration
- Location
- 2812355..2813176 (- strand)
- Gene Length
- 821 bp
- Nucleotides
-
ATGAACCTGCGTGCCGCCGGTCCGGGGTGGCTGTTCTGCCCTGCCGATCGTCCGGAACGCTTTGCGAAGGCTGCCGCCGCGGCCGACGTGGTGATTCTCGACCTCGAGGACGGCGTGGCCGAGGCGCAGAAGCCTGCCGCGCGCAATGCGTTGCGGGACACCCCGCTGGACCCGGAACGCACGGTGGTGCGTATCAATGCGGGCGGTACTGCTGATCAGGCCCGCGATCTGGAGGCCCTCGCAGGCACCGCCTATACCACGGTGATGCTGCCCAAGGCCGAATCGGCGGCCCAAGTCATCGAGCTTGCGCCGCGTGATGTCATCGCGCTGGTGGAGACCGCGCGCGGTGCCGTGTGCGCCGCCGAAATCGCCGCGGCCGATCCCACCGTGGGAATGATGTGGGGTGCCGAAGACTTGATCGCCACCCTTGGCGGTAGCTCGAGCCGGCGGGCCGACGGTGCCTATCGTGACGTGGCCCGACATGTCCGCTCGACCATCCTGCTCGCCGCGTCCGCGTTCGGCCGTCTCGCGCTCGATGCCGTACATCTGGATATCCTCGATGTCGAGGGCTTGCAGGAAGAGGCCAGAGACGCCGCGGCGGTGGGCTTTGACGTGACCGTGTGCATTCACCCGAGTCAGATCCCGGTGGTGCGCAAGGCCTATCGACCCAGCCACGAGAAGCTGGCCTGGGCTCGGCGGGTTTTGGCCGCGTCGCGAAGCGAGCGTGGGGCGTTCGCGTTCGAAGGCCAGATGGTCGACTCTCCAGTGCTCACGCACGCGGAAACGATGTTGCGGCGAGCCGGGGAAGCCACCTCCGAATG
- Drug Resistance
- Mutations
- Function
- May play a role in fatty acid biosynthesis. {ECO:0000305}.
- Family
-
HpcH/HpaI aldolase family, Citrate lyase beta subunit-like subfamily
- GO
-
- magnesium ion binding GO:0000287 molecular_function
- oxaloacetate metabolic process GO:0006107 biological_process
- lyase activity GO:0016829 molecular_function
- InterPro
1U5H
- Name
- Citrate lyase subunit beta-like protein (EC 4.1.-.-)
- Family
- HpcH/HpaI aldolase family, Citrate lyase beta subunit-like subfamily
- Protein Sequence
-
MNLRAAGPGWLFCPADRPERFAKAAAAADVVILDLEDGVAEAQKPAARNALRDTPLDPERTVVRINAGGTADQARDLEALAGTAYTTVMLPKAESAAQVIELAPRDVIALVETARGAVCAAEIAAADPTVGMMWGAEDLIATLGGSSSRRADGAYRDVARHVRSTILLAASAFGRLALDAVHLDILDVEGLQEEARDAAAVGFDVTVCIHPSQIPVVRKAYRPSHEKLAWARRVLAASRSERGAFAFEGQMVDSPVLTHAETMLRRAGEATSE
- Mass
- 28,886 Da
- Length
- 273 Aa
Summary
- Formic Acid DB01942
-
Acide formique | Ameisensäure | Aminic acid | bilorin | Formate | Formylic acid | Hydrogen carboxylic acid | Methanoic acid
-
-
Two-component system mtu02020
mtu02020Environmental Information Processing; Signal transduction
-
- The structure and computational analysis of Mycobacterium tuberculosis protein CitE suggest a novel enzymatic function.
- J Mol Biol. 2007 Jan 12;365(2):275-83. doi: 10.1016/j.jmb.2006.09.086. Epub 2006 Oct 3.
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.