Gene - combatTB X

Rv2565

Type: protein_coding
Name: Rv2565
Locus Name: Rv2565
Product: Conserved protein
Functional Category: Conserved hypotheticals
Location: 2884611..2886362 (+ strand)
Gene Length: 1751 bp
Nucleotides: TGACCACCGCGCGACGACGGCCCAAGCGGCGTGGTACCGATGCGCGAACCGCGCTGCGCAACGTTCCGATACTCGCCGATATCGACGACGAACAGCTCGAACGACTCGCAACCACCGTAGAACGCCGCCACGTGCCCGCTAACCAGTGGCTCTTTCATGCCGGAGAACCAGCGGACTCCATCTATATCGTCGACTCGGGGCGGTTCGTCGCTGTTGCCCCAGAGGGACACGTATTTGCTGAGATGGCATCCGGCGACTCGATCGGAGACCTGGGGGTGATCGCCGGGGCTGCCCGCTCAGCGGGAGTGCGAGCTCTGCGAGACGGCGTGGTGTGGAGGATCGCCGCGGAGACGTTTACCGACATGCTCGAGGCAACCCCGCTACTGCAATCGGCGATGCTGCGAGCGATGGCGAGAATGCTACGCCAGTCACGACCCGCCAAGACGGCTCGGCGTCCGCGGGTCATCGGCGTGGTATCGAACGGGGACACCGCCGCGGCCCCGATGGTCGACGCGATCGCTACTTCACTGGACTCGCACGGTCGAACTGCCGTGATTGCGCCGCCCGTCGAAACCACCTCCGCCGTTCAGGAGTACGACGAGCTCGTCGAGGCGTTCAGCGAAACCCTCGATCGCGCGGAGCGAAGCAACGATTGGGTCTTGGTGGTCGCCGACCGAGGCGCCGGCGACCTGTGGCGGCACTACGTTAGCGCGCAAAGCGACCGACTCGTGGTCCTGGTGGATCAACGGTATCCGCCGGATGCGGTCGATTCGCTTGCTACCCAACGGCCAGTGCACCTGATCACATGTCTGGCAGAACCGGATCCAAGTTGGTGGGATCGGTTGGCGCCGGTTTCGCATCATCCGGCCAACTCCGACGGCTTCGGTGCCCTTGCTCGCAGAATCGCCGGCCGATCGCTCGGCCTGGTGATGGCCGGTGGCGGAGCCCGGGGACTGGCGCATTTCGGTGTTTACCAAGAGCTCACCGAAGCCGGCGTCGTCATCGATCGGTTTGGCGGAACAAGTTCGGGTGCAATCGCTTCCGCAGCGTTCGCGCTGGGGATGGACGCCGGGGATGCGATCGCCGCGGCGCGAGAGTTCATCGCAGGAAGCGACCCACTCGGCGACTACACGATCCCAATATCCGCCCTCACGCGAGGTGGACGCGTCGATCGTCTGGTGCAGGGATTCTTCGGCAACACGTTGATCGAACATCTGCCCAGAGGGTTCTTCTCCGTCTCCGCCGACATGATCACCGGCGATCAGATCATCCATCGGCGGGGATCCGTCTCGGGCGCCGTGCGCGCATCGATCTCGATCCCCGGTCTCATCCCGCCAGTGCACAATGGCGAGCAGCTGCTCGTCGACGGTGGGCTGTTGAACAATCTGCCGGCCAACGTGATGTGCGCCGATACCGATGGCGAAGTCATCTGCGTCGACCTCCGCCGAACGTTCGTGCCGTCGAAGGGCTTTGGCCTGCTGCCGCCAATCGTTACGCCGCCCGGGCTCCTCCGGCGGCTTTTGACCGGCACGGATAACGCGCTACCACCGCTGCAAGAGACGTTGCTGCGCGCCTTCGACCTTGCCGCCTCCACCGCAAACCTGCGCGAGCTTCCTCGCGTTGCGGCCATCATCGAGCCCGACGTGTCGAAGATCGGAGTGTTGAACTTCAAGCAGATTGATGCCGCCCTAGAGGCTGGGCGGATGGCAGCCCGTGCGGCTTTGCAAGCACAGCCGGACCTGGTGCGCTGA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

NTE family

GO

phosphatidylcholine metabolic process GO:0046470 biological_process
cytosol GO:0005829 cellular_component
lysophospholipase activity GO:0004622 molecular_function
lipid catabolic process GO:0016042 biological_process

InterPro

UniProt: P9WIY7
GenBank: Rv2565
EnsemblBacteria: Rv2565
Mycobrowser: Rv2565

Summary

Name: Uncharacterized NTE family protein Rv2565
Family: NTE family
Protein Sequence: MTTARRRPKRRGTDARTALRNVPILADIDDEQLERLATTVERRHVPANQWLFHAGEPADSIYIVDSGRFVAVAPEGHVFAEMASGDSIGDLGVIAGAARSAGVRALRDGVVWRIAAETFTDMLEATPLLQSAMLRAMARMLRQSRPAKTARRPRVIGVVSNGDTAAAPMVDAIATSLDSHGRTAVIAPPVETTSAVQEYDELVEAFSETLDRAERSNDWVLVVADRGAGDLWRHYVSAQSDRLVVLVDQRYPPDAVDSLATQRPVHLITCLAEPDPSWWDRLAPVSHHPANSDGFGALARRIAGRSLGLVMAGGGARGLAHFGVYQELTEAGVVIDRFGGTSSGAIASAAFALGMDAGDAIAAAREFIAGSDPLGDYTIPISALTRGGRVDRLVQGFFGNTLIEHLPRGFFSVSADMITGDQIIHRRGSVSGAVRASISIPGLIPPVHNGEQLLVDGGLLNNLPANVMCADTDGEVICVDLRRTFVPSKGFGLLPPIVTPPGLLRRLLTGTDNALPPLQETLLRAFDLAASTANLRELPRVAAIIEPDVSKIGVLNFKQIDAALEAGRMAARAALQAQPDLVR
Mass: 62,124 Da
Length: 583 Aa

Rv2565 doesn't seem to be a targeted by any drug.

Rv2565 doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.