Gene - combatTB X

Rv2681

Type: protein_coding
Name: Rv2681
Locus Name: Rv2681
Product: Conserved hypothetical alanine rich protein
Functional Category: Conserved hypotheticals
Location: 2996739..2998055 (+ strand)
Gene Length: 1316 bp
Nucleotides: TGTGCCCCGAGCCGTCTCACGCGGGAGCTGCTGAGTCCGAAGGCACGGAATCGGAACCCACCCCCTTGCTCCGGCCCGCCGGTGGGATACCGGATCTGTGTGTGACCGTCGGTGAAATCGCCGCTGCCGCAGAACTACTGGACCGCGGGCGCGGACCGTTCGCGGTAGACGCCGAGCGGGCGTCGGGTTTCCGCTACTCCGGCCGCGCCTACCTGATTCAGATCCGGCGGGCCGAGGCCGGCACCGTACTGATCGACCCGGTCAGCCACGGCGGTGACCCGTTGACCGTGCTGGCGCCGGTCGCCGAGGTGCTCAGCACCAACGAGTGGATCCTGCACTCCGCCGATCAGGATCTGCCCTGTCTCGCCGAGGTCGGTATGCGACCGCCAGCGCTATACGACACCGAGCTTGCCGGGCGCCTGGCCGGGTTCGATCGAGTGAACCTGGCGGCCATGGTCGAGCGGTTACTTGGACTGGGATTGACCAAGGGCCACGGCGCGGCCGACTGGTCCAAGCGCCCGCTACCCTCGGCCTGGCTGAACTACGCGGCGTTGGACGTGGAACTGCTCATCGAACTACGCGCGGCGATCTCGCGGGTGCTGGCCGAGCAAGGCAAAACCGATTGGGCTGCGCAGGAATTCGAGCACCTGCGGTCGTTCGAATCAAGGCCACCCCCAGCGGCCGCCCGGCAGGACCGCTGGCGACGAACCTCGGGTATCCACAAAGTGCATGACCGGCGGGGGCTGGCCGCGGTCCGCGAATTGTGGACAGCGCGTGACCGAATCGCCCAGCGCCGCGACATCGCGCCCCGCCGGATCTTGCCGGACTCGGCCATTATCGATGCCGCCATCGCCGACCCAAAGTCAGTCGACGACCTTGTCGCGTTACCGGTGTTCGGCGGACGCAACCAACGTCGCAGCGCGGCTGTGTGGTGGGCGGCACTGGCAGCCGCACGCGAAAGCCCAGATCCGCCGGAGATCGCCGAACCGGCAAACGGGCCGCCGCCGCCGGGGCGGTGGGTCAGACGGAAACCGGCAGCCGCCGCACGGCTGGATGCGGCGCGCGCGGCGCTGACGGAGGTGTCGCAACGGGTGCGGGTACCGACCGAGAACCTGGTCTCACCTGATCTGGTGCGACGGCTGTGTTGGGAATGGGAGGACATCTCGCAGAGTTCTCCAGACCCGATTGCCGCTGTCGAGGCGTACCTGCGCACCGGCCAGGCACGGGCCTGGCAGCTCGAACTAGTGGTCCCCATCCTGACCGCGGCGTTGACAGGGGCTCCGGACGCCGGCGCCCAGGGCGATGATGGCTCTTAG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Unknown

GO

single-stranded RNA binding GO:0003727 molecular_function
3'-5'-exoribonuclease activity GO:0000175 molecular_function
nucleotide binding GO:0000166 molecular_function

InterPro

UniProt: I6XF17
GenBank: Rv2681
EnsemblBacteria: Rv2681
Mycobrowser: Rv2681

Summary

Name: Conserved hypothetical alanine rich protein
Family: Unknown
Protein Sequence: MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAALTGAPDAGAQGDDGS
Mass: 47,224 Da
Length: 438 Aa

Rv2681 doesn't seem to be a targeted by any drug.

Rv2681 doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.