Gene - combatTB X

Type: protein_coding
Name: ceoC
Locus Name: Rv2692
Product: TRK system potassium uptake protein CeoC
Functional Category: Cell wall and cell processes
Location: 3010024..3010686 (+ strand)
Gene Length: 662 bp
Nucleotides: TGAAAGTAGCTGTCGCCGGAGCGGGTGCGGTGGGCCGCTCGGTCACCCGCGAACTCGTGGAAAACGGACACGACATCACCCTGATCGAGCGCAACCCCGACCACCTCGACGCCGCCGCCATCCCGGAGGCGCATTGGCGGCTTGGCGATGCCTGCGAACTGAGCCTGCTGGAGTCGATTCACCTCGAAGAGTTCGACGTGGTCGTCGCCGCCACCGGGGACGACAAGGTCAACGTGGTGCTCAGCCTGCTAGCCAAGACCGAATTCGCGGTGCCGCGGGTGGTGGCCCGGGTCAACGATCCCCGCAACGAGTGGCTGTTCAACGACGCCTGGGGGGTCGACGTCGCGGTGTCCACACCCCGCATGCTGGCGTCGCTGATCGAAGAGGCCGTCACGATCGGCGACTTGGTGCGGCTGATGGAGTTCCGCACGGGTCAGGCCAATCTGGTAGAGATCACCCTGCCCGACAACACGCCGTGGGGCGGCAAACCGGTGCGCAAACTTCAGCTGCCGCGGGATGCCGCGCTGGTGACAATCCTGCGCGGGCCACGAGTCATCGTGCCGGAGGCCGACGAGCCGCTGGAAGGCGGCGACGAGTTGCTCTTCGTCGCAGTCACCGAAGCCGAGGAGGAGCTGAGCAGGCTGCTGCTGCCGTCCATGTAA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Part of a potassium transport system. {ECO:0000250}.

Family

Unknown

GO

InterPro

Summary

Name: Trk system potassium uptake protein TrkA (K(+)-uptake protein TrkA)
Family: Unknown
Protein Sequence: MKVAVAGAGAVGRSVTRELVENGHDITLIERNPDHLDAAAIPEAHWRLGDACELSLLESIHLEEFDVVVAATGDDKVNVVLSLLAKTEFAVPRVVARVNDPRNEWLFNDAWGVDVAVSTPRMLASLIEEAVTIGDLVRLMEFRTGQANLVEITLPDNTPWGGKPVRKLQLPRDAALVTILRGPRVIVPEADEPLEGGDELLFVAVTEAEEELSRLLLPSM
Mass: 23,947 Da
Length: 220 Aa

Rv2692 doesn't seem to be a targeted by any drug.

Rv2692 doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Novel selection for isoniazid (INH) resistance genes supports a role for NAD+-binding proteins in mycobacterial INH resistance.: Infect Immun. 1998 Nov;66(11):5099-106.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.