Gene - combatTB X

Rv2721c

Type: protein_coding
Name: Rv2721c
Locus Name: Rv2721c
Product: Possible conserved transmembrane alanine and glycine rich protein
Functional Category: Cell wall and cell processes
Location: 3032520..3034619 (- strand)
Gene Length: 2099 bp
Nucleotides: GTGAACGGGCAGAGAGGTCAATTGAGCACGCTGATCGGGCGTACGCTGCTCGGCTTGGCGGCCACGGCGGTGACCGCCGTGTTGCTGGCGCCCACGGTGGCGGCTTCGCCGATGGGCGATGCCGAGGACGCCATGATGGCCGCGTGGGAGAAGGCGGGTGGTGACACTTCAACACTTGGTGTCCGGAAAGGTGACGTTTACCCGATAGGCGACGGGTTCGCCCTGGACTTCGCCGGCGGCAAGATGTTTTTCACCCCGGCCACCGGTGCCAAATACCTCTACGGCCCGCTCCTGGACAAATACGAGTCGCTGGGCGGTGCAGCCGACAGCGATCTGGGATTCCCGACCATCAACGAGGTGCCCGGCCTTGCCGGACCCGACAGTCGCGTGAGCACGTTCTCCGCGGCCGACAACCCGGTGATTTTCTGGACGCCTGAACACGGTGCGTTCGTCGTGCGCGGCGCGCTGAATGCCGCGTGGGACAAGCTCGGCAGCTCGGGTGGCGTGCTGGGTGCCCCGGTCGGGGATGAAACCTACGACGGCGAGGTCACCGCCCAGAAGTTCAGCGGTGGTGAAGTCTCCTGGAACCGGGCAACCAAGGAGTTCACCACCGTTCCGGCGGTGCTGGCCGAGCAGCTGAAGGGTTTGCAGGTAGCGATCGATCCTTCCGCGGCGATCAACATGGCCTGGCGCGCAGCAGGTGGTGCCGCAGGTCCGCTGGGCGCCAAGAAGGGTGGGCAGTACCCGATCGGCGGAGACGGTATCGCCCAGGACTTCGTCGGTGGCAAGGTCTTCTTCAGCCCGGCAACCGGTGCAAACGCCGTCGAGGGTGAAATCCTGGCGAAGTACGAGTCGCTGGGCGGACCGGTCAGCAGCGACTTGGGTTTCCCCATCGCCAACGAAACTGATGGTGGTTTTGGGCCCTCCAGCCGGATCGTCAGGTTCTCCGCGGCCGACAAGCCGGTGATTTTCTGGACTCCGGACCACGGCGCGTTCGTCGTGCGCGGAGCCATGGTGGCCGCGTGGGACAAGCTGCGCGGCCCCAACGGCAAGCTCGGCGCCCCGGTCGGCGACCAGACCGTCGACGGCGATGTTGTCTCACAGAAATTCACCGGCGGCATGATTTCGTGGAACCGTGCAAAAAACACATTCACTACGGATCCCGCTAACCTAGCGCCCTTGCTGTCCGGTCTGCAGGTGTCAGGGCAGAACCAGCCAAGTACTTCGGCGATGCCCCCACCCGGCAAGAAGTTCACCTGGCATTGGTGGTGGTTAGGGGCCGCCGCCCTGGGGGTGCTCCTGGTCGTGATGGTGGCGTTGGTGGTGTTCGGATTGCGTCGGCGTCGACGTGGGTACGACGCCGCTGCTTACGACGATGACCGCGCTGGGGATGTCGAGTACGGTACCGCCGCTGATGGAGACTGGCCGCCCGACGAGGACTTCGGTTCAGAGCATTTCGGTTTCGGCGACCAGTTCCCGCCGGAACCTGTGGCGCCGGACGCCGGGTCCACACCGCGGGTCAGCTGGCCGCGCGGCGCCGGGGCGGCTGTCGGTGATGCCGAGCATCTTCCGGGTGAGGAGGGCTACGGCAGCGACTTGCTGTCCGGCCCCAGCAACGTCGGGGTCGAGGAGGAAGACACCGATGCGGTGGACACCACGCCGACACCCGTTGTGTCGCAGGCCGACCTTTCCGAAGTCGGTCCCGATCTCATTGTTCCTGAGCGAGTGGTTCCGGAGACTTTCGTTCCGCAAGCCTTTGTTCCGGAAGCAGTGGCGCCTGAAGCGGTGCCGCCCGATGTCCACGCTGCCGATCTTGCTGACACTGGGTTGCCGGCGGCGGCTGTATCCGCAGCTGAAGACAGAGGCGGGCGGCACGCGGCCGCAGAACCGCCGGAACCGCCGAGTGCGGGCGTGCGCCCGGCAATTCATCTGCCGCTCGAGGACCCATACCAGATGCCGAACGGCTATCCCGTCAAAGCCAGTGTGAGCTTCGGCCTGTATTACCCACCCGGCAGTGCGCTATACCACGACACGCTGGCCGAACTCTGGTTCGCCAGTGAAGAAGTGGCACAAGTCAACGGCTTCATTAGGGCGGATTG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Unknown

GO

integral component of membrane GO:0016021 cellular_component

InterPro

IPR013207

UniProt: I6XF52
GenBank: Rv2721c
EnsemblBacteria: Rv2721c
Mycobrowser: Rv2721c

Summary

Name: Possible conserved transmembrane alanine and glycine rich protein
Family: Unknown
Protein Sequence: MNGQRGQLSTLIGRTLLGLAATAVTAVLLAPTVAASPMGDAEDAMMAAWEKAGGDTSTLGVRKGDVYPIGDGFALDFAGGKMFFTPATGAKYLYGPLLDKYESLGGAADSDLGFPTINEVPGLAGPDSRVSTFSAADNPVIFWTPEHGAFVVRGALNAAWDKLGSSGGVLGAPVGDETYDGEVTAQKFSGGEVSWNRATKEFTTVPAVLAEQLKGLQVAIDPSAAINMAWRAAGGAAGPLGAKKGGQYPIGGDGIAQDFVGGKVFFSPATGANAVEGEILAKYESLGGPVSSDLGFPIANETDGGFGPSSRIVRFSAADKPVIFWTPDHGAFVVRGAMVAAWDKLRGPNGKLGAPVGDQTVDGDVVSQKFTGGMISWNRAKNTFTTDPANLAPLLSGLQVSGQNQPSTSAMPPPGKKFTWHWWWLGAAALGVLLVVMVALVVFGLRRRRRGYDAAAYDDDRAGDVEYGTAADGDWPPDEDFGSEHFGFGDQFPPEPVAPDAGSTPRVSWPRGAGAAVGDAEHLPGEEGYGSDLLSGPSNVGVEEEDTDAVDTTPTPVVSQADLSEVGPDLIVPERVVPETFVPQAFVPEAVAPEAVPPDVHAADLADTGLPAAAVSAAEDRGGRHAAAEPPEPPSAGVRPAIHLPLEDPYQMPNGYPVKASVSFGLYYPPGSALYHDTLAELWFASEEVAQVNGFIRAD
Mass: 72,372 Da
Length: 699 Aa

Rv2721c doesn't seem to be a targeted by any drug.

Rv2721c doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.