ribF
- Type
- protein_coding
- Name
- ribF
- Locus Name
-
Rv2786c
- Product
-
Probable bifunctional FAD synthetase/riboflavin biosynthesis protein RibF: riboflavin kinase (flavokinase) + FMN adenylyltransferase (FAD pyrophosphorylase) (FAD synthetase)(FAD diphosphorylase) (flavin adenine dinucleotide synthetase)
- Functional Category
-
Intermediary metabolism and respiration
- Location
- 3093905..3094900 (- strand)
- Gene Length
- 995 bp
- Nucleotides
-
GTGCGCCGTAGGCTTGCGATCGTGCAGCGCTGGCGTGGCCAGGACGAGATCCCGACGGATTGGGGCAGATGCGTGCTCACCATCGGGGTATTTGACGGCGTGCACCGCGGGCACGCCGAACTGATCGCGCACGCGGTCAAGGCCGGCCGCGCTCGCGGTGTACCGGCCGTGCTGATGACGTTCGACCCGCACCCGATGGAGGTGGTCTATCCAGGCAGTCACCCGGCGCAGCTGACCACCCTGACCCGACGCGCGGAGCTCGTTCAAGACTTGGGCATCGAAGTGTTCCTGGTGATGCCGTTCACCACCGATTTCATGAAGCTCACGCCGGATCGCTTCATCCATGAGCTGCTCGTCGAGCACCTACATGTGGTGGAGGTCGTCGTCGGCGAGAACTTCACCTTCGGCAAAAAGGCCGCCGGCAATGTCGACACGCTGCGTCGGGCTGGCGAGCGGTTCGGGTTCGCGGTGGAATCGATGTCGTTGGTGTCCGAGCACCACAGCAACGAGACCGTGACGTTCTCCTCCACCTACATCCGGTCCTGCGTGGACGCCGGCGACATGGTGGCGGCCATGGAAGCTCTGGGCCGACCGCACCGCGTGGAGGGGGTTGTGGTACGCGGTGAGGGGCGGGGCGCGGAGCTGGGCTTTCCCACCGCGAACGTGGCGCCGCCGATGTATTCGGCGATTCCGGCCGACGGCGTGTACGCCGCTTGGTTCACGGTGCTCGGGCATGGGCCGGTGACCGGCACGGTCGTCCCGGGTGAGCGCTACCAGGCCGCGGTGTCGGTCGGGACCAATCCCACCTTCTCCGGACGCACCCGCACCGTCGAAGCGTTCGTGCTGGACACCACCGCTGACCTCTACGGTCAACATGTGGCCTTGGACTTCGTCGGGCGTATCCGCGGCCAGAAGAAGTTCGAATCGGTGCGCCAGCTGGTCGCTGCGATGGGTGCCGATACCGAGCGGGCACGTGACCTGTTGTCTACGGGTTG
- Drug Resistance
- Mutations
- Function
- Unknown
- Family
-
RibF family
- GO
-
- FMN biosynthetic process GO:0009398 biological_process
- riboflavin biosynthetic process GO:0009231 biological_process
- FMN adenylyltransferase activity GO:0003919 molecular_function
- FAD biosynthetic process GO:0006747 biological_process
- riboflavin kinase activity GO:0008531 molecular_function
- ATP binding GO:0005524 molecular_function
- InterPro
Summary
- Name
- Riboflavin biosynthesis protein [Includes: Riboflavin kinase (EC 2.7.1.26) (Flavokinase); FMN adenylyltransferase (EC 2.7.7.2) (FAD pyrophosphorylase) (FAD synthase)]
- Family
- RibF family
- Protein Sequence
-
MRRRLAIVQRWRGQDEIPTDWGRCVLTIGVFDGVHRGHAELIAHAVKAGRARGVPAVLMTFDPHPMEVVYPGSHPAQLTTLTRRAELVQDLGIEVFLVMPFTTDFMKLTPDRFIHELLVEHLHVVEVVVGENFTFGKKAAGNVDTLRRAGERFGFAVESMSLVSEHHSNETVTFSSTYIRSCVDAGDMVAAMEALGRPHRVEGVVVRGEGRGAELGFPTANVAPPMYSAIPADGVYAAWFTVLGHGPVTGTVVPGERYQAAVSVGTNPTFSGRTRTVEAFVLDTTADLYGQHVALDFVGRIRGQKKFESVRQLVAAMGADTERARDLLSTG
- Mass
- 36,090 Da
- Length
- 331 Aa
Rv2786c doesn't seem to be a targeted by any drug.
-
-
Riboflavin metabolism mtu00740
mtu00740PATHWAY_MAP mtu00740 Riboflavin metabolism
-
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.