nusA
- Type
- protein_coding
- Name
- nusA
- Locus Name
-
Rv2841c
- Product
-
Probable N utilization substance protein A NusA
- Functional Category
-
Information pathways
- Location
- 3148385..3149428 (- strand)
- Gene Length
- 1043 bp
- Nucleotides
-
ATGAACATCGACATGGCTGCTCTGCATGCCATCGAGGTGGACCGGGGTATCTCGGTCAATGAACTGCTCGAAACGATCAAGTCCGCGCTGTTGACTGCCTACCGGCACACCCAAGGTCACCAGACCGATGCGCGCATCGAGATCGACCGGAAAACCGGTGTCGTTCGGGTGATCGCCCGTGAGACCGATGAGGCTGGCAATCTCATCAGCGAGTGGGACGACACTCCAGAGGGCTTCGGCCGGATCGCCGCCACGACGGCACGCCAAGTGATGTTGCAGCGATTCCGCGACGCCGAGAACGAGCGCACCTACGGCGAGTTCTCCACCCGCGAGGGCGAGATCGTTGCGGGAGTGATCCAGCGCGATAGCCGGGCCAACGCCCGCGGTCTGGTCGTCGTCCGGATTGGCACCGAGACCAAGGCTTCCGAGGGTGTGATCCCGGCCGCTGAGCAGGTACCGGGGGAGAGCTATGAACATGGCAACCGGCTGCGCTGCTACGTAGTTGGTGTAACCCGAGGTGCCCGCGAGCCGCTGATTACGCTGTCGCGCACGCACCCCAATCTGGTGCGCAAGCTGTTCTCGCTGGAAGTCCCCGAGATCGCCGACGGATCGGTGGAGATCGTCGCGGTGGCCCGGGAGGCCGGCCACCGCTCCAAGATCGCTGTGCGGTCCAACGTTGCCGGCTTGAACGCCAAGGGTGCTTGCATCGGTCCGATGGGGCAACGGGTCCGCAACGTGATGAGCGAGCTGTCCGGGGAGAAGATCGACATCATCGACTATGACGACGATCCGGCGCGTTTTGTCGCCAACGCGTTGTCGCCGGCCAAGGTGGTGTCGGTGTCGGTGATCGACCAGACCGCCCGGGCCGCCCGCGTGGTGGTGCCCGATTTCCAATTGTCGCTGGCAATCGGAAAGGAAGGGCAGAACGCCCGGCTGGCTGCCCGGCTCACCGGGTGGCGTATCGATATTCGCGGCGATGCGCCGCCGCCCCCGCCCGGTCAGCCCGAACCCGGAGTCAGCCGCGGTATGGCGCACGACCGCTA
- Drug Resistance
- Mutations
- Function
- Participates in both transcription termination and antitermination. {ECO:0000255|HAMAP-Rule:MF_00945}.
- Family
-
NusA family
- GO
-
- DNA-binding transcription factor activity GO:0003700 molecular_function
- RNA binding GO:0003723 molecular_function
- cell wall GO:0005618 cellular_component
- cytosol GO:0005829 cellular_component
- DNA-templated transcription, termination GO:0006353 biological_process
- plasma membrane GO:0005886 cellular_component
- transcription antitermination GO:0031564 biological_process
- InterPro
1K0R
- Name
- Transcription termination/antitermination protein NusA
- Family
- NusA family
- Protein Sequence
-
MNIDMAALHAIEVDRGISVNELLETIKSALLTAYRHTQGHQTDARIEIDRKTGVVRVIARETDEAGNLISEWDDTPEGFGRIAATTARQVMLQRFRDAENERTYGEFSTREGEIVAGVIQRDSRANARGLVVVRIGTETKASEGVIPAAEQVPGESYEHGNRLRCYVVGVTRGAREPLITLSRTHPNLVRKLFSLEVPEIADGSVEIVAVAREAGHRSKIAVRSNVAGLNAKGACIGPMGQRVRNVMSELSGEKIDIIDYDDDPARFVANALSPAKVVSVSVIDQTARAARVVVPDFQLSLAIGKEGQNARLAARLTGWRIDIRGDAPPPPPGQPEPGVSRGMAHDR
- Mass
- 37,642 Da
- Length
- 347 Aa
Summary
Rv2841c doesn't seem to be a targeted by any drug.
Rv2841c doesn't seem to be involved in any pathway.
- Structure of a Mycobacterium tuberculosis NusA-RNA complex.
- EMBO J. 2005 Oct 19;24(20):3576-87. doi: 10.1038/sj.emboj.7600829. Epub 2005 Sep 29.
- Crystal structure of the transcription elongation/anti-termination factor NusA from Mycobacterium tuberculosis at 1.7 A resolution.
- J Mol Biol. 2001 Dec 14;314(5):1087-95. doi: 10.1006/jmbi.2000.5144.
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.