efpA
- Type
- protein_coding
- Name
- efpA
- Locus Name
-
Rv2846c
- Product
-
Possible integral membrane efflux protein EfpA
- Functional Category
-
Cell wall and cell processes
- Location
- 3153039..3154631 (- strand)
- Gene Length
- 1592 bp
- Nucleotides
-
ATGACGGCTCTCAACGACACAGAGCGGGCGGTCCGTAACTGGACAGCCGGACGCCCACACCGTCCGGCCCCGATGCGCCCGCCGCGCTCGGAGGAGACCGCTTCAGAGCGCCCCAGCAGGTACTACCCGACTTGGCTGCCCTCGCGCAGCTTTATCGCTGCGGTTATTGCTATCGGCGGGATGCAGCTGCTGGCGACCATGGACAGCACCGTCGCCATCGTCGCGCTACCTAAGATTCAAAACGAGCTGAGCTTGTCTGATGCCGGCCGCAGCTGGGTGATCACCGCCTACGTGCTGACCTTCGGCGGGCTGATGCTGCTCGGCGGCCGGCTTGGCGACACCATCGGGCGCAAACGCACCTTCATTGTTGGCGTTGCGCTATTCACCATCTCGTCGGTGCTGTGCGCGGTCGCCTGGGACGAGGCGACGTTGGTGATCGCCCGGTTGTCCCAGGGTGTGGGGTCGGCCATCGCATCTCCGACCGGTCTGGCGCTGGTGGCGACCACGTTCCCCAAGGGACCTGCCCGCAACGCCGCGACGGCGGTGTTCGCCGCGATGACCGCGATCGGGTCGGTGATGGGGCTGGTGGTCGGCGGAGCACTGACCGAGGTGTCATGGCGGTGGGCGTTCCTGGTGAACGTGCCGATCGGGCTGGTGATGATCTACCTGGCCCGCACCGCCCTACGGGAAACCAACAAAGAACGGATGAAGCTCGACGCCACCGGGGCCATACTGGCCACGCTGGCATGCACCGCGGCGGTTTTCGCCTTCTCGATCGGTCCTGAAAAGGGCTGGATGTCAGGCATTACCATCGGTTCGGGCCTGGTGGCCTTGGCGGCCGCTGTCGCGTTTGTCATCGTGGAGCGCACTGCCGAGAACCCCGTCGTGCCGTTCCACTTGTTCCGCGACCGCAACCGGTTGGTCACGTTCAGCGCGATCCTGTTGGCCGGCGGCGTCATGTTCAGCCTGACCGTCTGCATCGGCCTGTACGTGCAGGACATCTTGGGCTACAGCGCGCTACGCGCGGGCGTAGGTTTCATCCCGTTCGTCATCGCGATGGGAATCGGCCTAGGTGTGTCCTCGCAGCTGGTGTCCCGGTTTTCGCCACGGGTGTTGACCATCGGCGGCGGATATCTGCTATTCGGCGCCATGCTGTACGGCTCATTTTTCATGCACCGTGGTGTGCCCTACTTCCCCAACCTGGTCATGCCGATCGTCGTCGGCGGGATTGGCATCGGCATGGCCGTCGTCCCGCTGACTCTGTCGGCGATCGCTGGCGTCGGCTTCGACCAGATCGGTCCGGTATCGGCAATTGCGCTGATGCTGCAGAGCCTGGGCGGTCCGCTGGTGCTCGCCGTCATCCAGGCTGTGATCACGTCGCGCACGCTGTACCTGGGCGGTACCACCGGTCCGGTGAAGTTCATGAACGACGTGCAGTTGGCCGCGCTTGACCACGCCTACACCTACGGCCTGCTGTGGGTGGCCGGAGCGGCCATCATCGTCGGCGGTATGGCGCTGTTTATCGGGTATACGCCGCAGCAGGTTGCCCATGCGCAGGAGGTCAAGGAAGCGATCGACGCCGGCGAGCTGTA
- Drug Resistance
- Mutations
- Function
- Unknown
- Family
-
Major facilitator superfamily
- GO
-
- transmembrane transport GO:0055085 biological_process
- plasma membrane GO:0005886 cellular_component
- integral component of membrane GO:0016021 cellular_component
- InterPro
Summary
- Name
- Uncharacterized MFS-type transporter EfpA (Efflux protein A)
- Family
- Major facilitator superfamily
- Protein Sequence
-
MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL
- Mass
- 55,580 Da
- Length
- 530 Aa
Rv2846c doesn't seem to be a targeted by any drug.
Rv2846c doesn't seem to be involved in any pathway.
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Transcriptional regulation of multi-drug tolerance and antibiotic-induced responses by the histone-like protein Lsr2 in M. tuberculosis.
- PLoS Pathog. 2007 Jun;3(6):e87. doi: 10.1371/journal.ppat.0030087.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.
- Mycobacterium tuberculosis efpA encodes an efflux protein of the QacA transporter family.
- Clin Diagn Lab Immunol. 1997 Jan;4(1):23-32.