Gene - combatTB X

dipZ

Type: protein_coding
Name: dipZ
Locus Name: Rv2874
Product: Possible integral membrane C-type cytochrome biogenesis protein DipZ
Functional Category: Intermediary metabolism and respiration
Location: 3184847..3186934 (+ strand)
Gene Length: 2087 bp
Nucleotides: TGGTTGAGTCGAGACGAGCTGCTGCGGCGGCTTCGGCATACGCAAGCAGATGCGGGATTGCACCCGCGACCTCGCAACGCTCACTGGCGACACCACCGACGATCTCGGTCCCGTCCGGTGAGGGCCGCTGCCGTTGCCACGTCGCAAGGGGTGCCGGTCGTGACCCACGACGGCGACTTCGACGCCGTCGATGGTGTGGCCGATGTGGCTATCATTCGCATCTGACGGGTGGCGAGTTCGACGTGAACCGACTCTGTCAACAGCGCTCGCGTGAGCGGTCCTGCCAACTCGTTGCCGTCCCGGCAGATCCAAGACCTAAACGGCAACGAATAACCGATGTGTTGACCCTCGCACTAGTCGGCTTCCTCGGCGGCCTCATCACCGGAATATCACCATGCATTCTGCCGGTCCTGCCAGTAATCTTCTTCTCCGGCGCGCAGAGCGTCGATGCAGCGCAGGTGGCGAAACCCGAAGGCGCCGTAGCAGTCCGGCGCAAACGTGCGCTATCAGCGACATTGCGGCCCTACCGGGTGATCGGTGGTCTGGTGCTCAGTTTCGGCATGGTCACCCTGCTCGGCTCGGCATTGCTGTCAGTGCTGCATCTACCGCAGGACGCCATCCGCTGGGCCGCACTGGTCGCCTTGGTGGCAATCGGCGCCGGCCTCATTTTCCCGCGGTTTGAACAACTTCTGGAAAAACCGTTCTCCCGTATTCCGCAGAAGCAAATCGTCACTCGCAGCAACGGTTTCGGGCTGGGTCTAGCCCTGGGCGTGTTGTATGTCCCCTGCGCCGGCCCGATTCTAGCTGCGATCGTCGTGGCCGGGGCTACTGCCACCATCGGGTTGGGAACCGTCGTGCTCACCGCGACATTCGCACTCGGAGCCGCGTTGCCGTTGTTGTTCTTCGCCCTCGCCGGCCAACGGATAGCTGAGCGGGTGGGCGCTTTTCGGCGCCGCCAGCGTGAGATCAGGATCGCCACCGGTTCCGTGACGATCCTGCTGGCGGTGGCGTTGGTGTTCGATCTGCCGGCCGCGCTGCAGCGGGCTATTCCTGACTACACCGCATCGCTGCAGCAGCAGATCAGCACCGGCACGGAGATACGGGAACAACTGAACCTTGGCGGCATCGTCAACGCCCAGAACGCACAGCTGTCGAATTGCAGCGACGGGGCCGCACAACTCGAAAGCTGCGGCACTGCACCAGATCTCAAAGGCATCACCGGCTGGCTCAACACGCCCGGCAACAAGCCGATCGACCTGAAATCATTGCGTGGCAAGGTGGTGCTGATTGACTTTTGGGCCTACTCCTGCATTAACTGCCAACGGGCCATCCCCCACGTCGTCGGTTGGTATCAGGCCTACAAAGACAGTGGTTTGGCGGTCATCGGCGTGCACACCCCCGAGTACGCTTTCGAGAAGGTCCCGGGCAACGTCGCCAAAGGCGCGGCCAATCTGGGCATCAGCTATCCGATTGCGCTCGACAACAACTACGCCACTTGGACCAACTACCGGAATCGCTATTGGCCCGCCGAGTATCTGATCGACGCTACCGGGACGGTGCGGCACATCAAGTTCGGAGAAGGCGATTACAACGTCACCGAGACGTTGGTCAGGCAGTTGCTCAACGATGCCAAGCCCGGCGTCAAACTCCCCCAGCCCAGCAGCACCACCACGCCCGACCTTACCCCGCGGGCCGCACTTACTCCCGAGACGTACTTCGGAGTCGGCAAGGTGGTCAACTACGGCGGCGGCGGCGCATATGACGAAGGGTCGGCCGTGTTTGACTACCCGCCCAGTTTGGCAGCCAACAGCTTTGCACTGCGCGGCCGGTGGGCGCTGGACTATCAGGGTGCCACGTCCGACGGCAACGACGCCGCTATCAAATTGAATTACCACGCCAAAGACGTCTACATCGTTGTCGGTGGCACCGGCACCCTCACGGTCGTGAGGGACGGAAAGCCAGCCACACTACCGATCAGCGGGCCGCCGACCACCCATCAGGTGGTCGCCGGCTATCGGCTGGCGTCCGAAACACTTGAGGTGCGGCCCAGCAAGGGGCTACAGGTTTTTTCCTTCACCTACGGATGA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Unknown

GO

cytochrome complex assembly GO:0017004 biological_process
plasma membrane GO:0005886 cellular_component
cell redox homeostasis GO:0045454 biological_process
oxidoreductase activity GO:0016491 molecular_function
antioxidant activity GO:0016209 molecular_function
integral component of membrane GO:0016021 cellular_component

InterPro

UniProt: P9WG63
GenBank: Rv2874
EnsemblBacteria: Rv2874
Mycobrowser: Rv2874

Summary

Name: Protein DipZ
Family: Unknown
Protein Sequence: MVESRRAAAAASAYASRCGIAPATSQRSLATPPTISVPSGEGRCRCHVARGAGRDPRRRLRRRRWCGRCGYHSHLTGGEFDVNRLCQQRSRERSCQLVAVPADPRPKRQRITDVLTLALVGFLGGLITGISPCILPVLPVIFFSGAQSVDAAQVAKPEGAVAVRRKRALSATLRPYRVIGGLVLSFGMVTLLGSALLSVLHLPQDAIRWAALVALVAIGAGLIFPRFEQLLEKPFSRIPQKQIVTRSNGFGLGLALGVLYVPCAGPILAAIVVAGATATIGLGTVVLTATFALGAALPLLFFALAGQRIAERVGAFRRRQREIRIATGSVTILLAVALVFDLPAALQRAIPDYTASLQQQISTGTEIREQLNLGGIVNAQNAQLSNCSDGAAQLESCGTAPDLKGITGWLNTPGNKPIDLKSLRGKVVLIDFWAYSCINCQRAIPHVVGWYQAYKDSGLAVIGVHTPEYAFEKVPGNVAKGAANLGISYPIALDNNYATWTNYRNRYWPAEYLIDATGTVRHIKFGEGDYNVTETLVRQLLNDAKPGVKLPQPSSTTTPDLTPRAALTPETYFGVGKVVNYGGGGAYDEGSAVFDYPPSLAANSFALRGRWALDYQGATSDGNDAAIKLNYHAKDVYIVVGGTGTLTVVRDGKPATLPISGPPTTHQVVAGYRLASETLEVRPSKGLQVFSFTYG
Mass: 74,168 Da
Length: 695 Aa

Rv2874 doesn't seem to be a targeted by any drug.

Rv2874 doesn't seem to be involved in any pathway.

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.