Gene - combatTB X

Type: protein_coding
Name: mpt70
Locus Name: Rv2875
Product: Major secreted immunogenic protein Mpt70
Functional Category: Cell wall and cell processes
Location: 3187030..3187611 (+ strand)
Gene Length: 581 bp
Nucleotides: TGAAGGTAAAGAACACAATTGCGGCAACCAGTTTCGCGGCGGCCGGCCTGGCGGCTCTGGCGGTGGCTGTCTCACCGCCGGCGGCCGCAGGCGATCTGGTGGGCCCGGGCTGCGCGGAATACGCGGCAGCCAATCCCACTGGGCCGGCCTCGGTGCAGGGAATGTCGCAGGACCCGGTCGCGGTGGCGGCCTCGAACAATCCGGAGTTGACAACGCTGACGGCTGCACTGTCGGGCCAGCTCAATCCGCAAGTAAACCTGGTGGACACCCTCAACAGCGGTCAGTACACGGTGTTCGCACCGACCAACGCGGCATTTAGCAAGCTGCCGGCATCCACGATCGACGAGCTCAAGACCAATTCGTCACTGCTGACCAGCATCCTGACCTACCACGTAGTGGCCGGCCAAACCAGCCCGGCCAACGTCGTCGGCACCCGTCAGACCCTCCAGGGCGCCAGCGTGACGGTGACCGGTCAGGGTAACAGCCTCAAGGTCGGTAACGCCGACGTCGTCTGTGGTGGGGTGTCTACCGCCAACGCGACGGTGTACATGATTGACAGCGTGCTAATGCCTCCGGCGTAA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Unknown

GO

InterPro

Summary

Name: Immunogenic protein MPT70
Family: Unknown
Protein Sequence: MKVKNTIAATSFAAAGLAALAVAVSPPAAAGDLVGPGCAEYAAANPTGPASVQGMSQDPVAVAASNNPELTTLTAALSGQLNPQVNLVDTLNSGQYTVFAPTNAAFSKLPASTIDELKTNSSLLTSILTYHVVAGQTSPANVVGTRQTLQGASVTVTGQGNSLKVGNADVVCGGVSTANATVYMIDSVLMPPA
Mass: 19,073 Da
Length: 193 Aa

Rv2875 doesn't seem to be a targeted by any drug.

Rv2875 doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.
Cloning and sequencing of a unique antigen MPT70 from Mycobacterium tuberculosis H37Rv and expression in BCG using E. coli-mycobacteria shuttle vector.: Scand J Immunol. 1995 Mar;41(3):281-7.