Gene - combatTB X

PPE45

Type: protein_coding
Name: PPE45
Locus Name: Rv2892c
Product: PPE family protein PPE45
Functional Category: Pe/ppe
Location: 3200794..3202020 (- strand)
Gene Length: 1226 bp
Nucleotides: TTGGACTTTGGGGTGTTGCCGCCCGAGATCAACTCCGGTCGAATGTACGCAGGTCCGGGATCGGGGCCCATGATGGCCGCCGCGGCGGCCTGGGATAGTTTGGCGGCTGAATTGGGCTTGGCCGCCGGCGGCTACCGGTTGGCTATCTCGGAGCTGACCGGTGCGTACTGGGCGGGGCCCGCAGCGGCGTCGATGGTGGCCGCGGTCACGCCTTATGTGGCGTGGCTCAGCGCCACCGCCGGTCAGGCTGAACAGGCGGGCATGCAGGCCAGAGCGGCCGCGGCAGCCTATGAGCTGGCGTTTGCGATGACGGTGCCCCCGCCGGTGGTCGTTGCCAACCGCGCGCTGTTGGTGGCGCTGGTCGCGACCAACTTTTTCGGGCAGAACACCCCGGCGATCGCGGCCACCGAGGCCCAATACGCCGAGATGTGGGCCCAAGACGCTGCCGCCATGTACGCCTATGCGGGCTCCGCGGCAATCGCCACGGAGTTGACCCCGTTCACCGCGGCGCCAGTGACTACCAGCCCTGCCGCGCTGGCCGGCCAGGCGGCGGCGACGGTATCGTCGACGGTCCCACCGCTGGCCACCACCGCCGCGGTGCCCCAACTGTTGCAGCAACTCTCGTCGACGTCACTGATCCCGTGGTACTCGGCATTGCAGCAATGGCTCGCGGAGAATCTTCTCGGTCTCACGCCTGACAACAGGATGACGATCGTTCGGTTGCTGGGCATCAGCTACTTCGACGAAGGGCTACTGCAATTCGAGGCTTCGCTCGCCCAGCAAGCGATCCCGGGCACCCCGGGCGGCGCCGGTGACTCGGGATCCTCGGTGCTTGACAGCTGGGGTCCAACCATCTTCGCCGGCCCGCGGGCGAGCCCAAGTGTGGCAGGCGGCGGTGCTGTTGGCGGGGTTCAGACGCCCCAGCCGTACTGGTACTGGGCACTAGACCGAGAAAGCATTGGCGGATCGGTATCGGCCGCTTTGGGGAAGGGGAGCTCGGCTGGTTCATTGTCGGTGCCACCCGATTGGGCCGCCCGCGCTCGATGGGCAAACCCAGCGGCCTGGCGGTTGCCGGGCGACGATGTCACCGCCCTGCGCGGCACCGCGGAAAACGCCCTGCTTCGGGGATTTCCGATGGCCAGCGCCGGCCAGAGCACCGGCGGCGGCTTCGTTCACAAATACGGGTTCCGCTTGGCGGTAATGCAGCGTCCGCCCTTCGCTGGATA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Mycobacterial PPE family

GO

plasma membrane GO:0005886 cellular_component
integral component of membrane GO:0016021 cellular_component

InterPro

UniProt: P9WHZ1
GenBank: Rv2892c
EnsemblBacteria: Rv2892c
Mycobrowser: Rv2892c

Summary

Name: Uncharacterized PPE family protein PPE45
Family: Mycobacterial PPE family
Protein Sequence: MDFGVLPPEINSGRMYAGPGSGPMMAAAAAWDSLAAELGLAAGGYRLAISELTGAYWAGPAAASMVAAVTPYVAWLSATAGQAEQAGMQARAAAAAYELAFAMTVPPPVVVANRALLVALVATNFFGQNTPAIAATEAQYAEMWAQDAAAMYAYAGSAAIATELTPFTAAPVTTSPAALAGQAAATVSSTVPPLATTAAVPQLLQQLSSTSLIPWYSALQQWLAENLLGLTPDNRMTIVRLLGISYFDEGLLQFEASLAQQAIPGTPGGAGDSGSSVLDSWGPTIFAGPRASPSVAGGGAVGGVQTPQPYWYWALDRESIGGSVSAALGKGSSAGSLSVPPDWAARARWANPAAWRLPGDDVTALRGTAENALLRGFPMASAGQSTGGGFVHKYGFRLAVMQRPPFAG
Mass: 41,469 Da
Length: 408 Aa

Rv2892c doesn't seem to be a targeted by any drug.

Rv2892c doesn't seem to be involved in any pathway.

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.