dacB2
- Type
- protein_coding
- Name
- dacB2
- Locus Name
-
Rv2911
- Product
-
Probable penicillin-binding protein DacB2 (D-alanyl-D-alanine carboxypeptidase) (DD-peptidase) (DD-carboxypeptidase) (PBP) (DD-transpeptidase) (serine-type D-ala-D-ala carboxypeptidase) (D-amino acid hydrolase)
- Functional Category
-
Cell wall and cell processes
- Location
- 3218339..3219214 (+ strand)
- Gene Length
- 875 bp
- Nucleotides
-
TGCGAAAGCTCATGACCGCGACCGCCGCGCTCTGTGCCTGCGCAGTCACCGTCAGTGCGGGTGCCGCGTGGGCCGATGCCGACGTGCAGCCGGCCGGCTCCGTGCCGATCCCCGATGGCCCGGCTCAGACCTGGATCGTGGCCGACCTCGATAGCGGTCAGGTGCTAGCCGGCCGCGACCAAAACGTGGCCCATCCGCCCGCGAGCACCATCAAGGTGCTGTTGGCGCTGGTGGCACTCGACGAGCTGGACCTGAACTCCACGGTCGTCGCCGACGTCGCCGACACACAGGCCGAGTGCAACTGCGTCGGCGTCAAACCGGGGCGCAGCTACACCGCGCGCCAGCTGCTCGACGGCCTGTTGCTGGTGTCGGGCAACGACGCCGCCAACACGTTGGCGCACATGCTGGGTGGCCAAGACGTCACCGTGGCCAAGATGAACGCCAAAGCCGCCACCCTAGGTGCGACGTCCACCCACGCGACGACGCCGTCCGGCCTAGACGGACCCGGCGGCTCCGGGGCGTCCACCGCGCACGACCTGGTGGTCATCTTCCGGGCCGCGATGGCCAATCCGGTGTTCGCGCAGATCACCGCCGAGCCCTCGGCGATGTTCCCCAGCGATAACGGCGAACAGCTGATCGTCAACCAGGACGAGCTGCTGCAGCGGTACCCGGGCGCGATCGGCGGCAAGACGGGCTACACCAACGCCGCTCGCAAGACGTTCGTGGGTGCCGCCGCCCGCGGCGGCCGCCGCCTGGTGATCGCCATGATGTACGGGCTGGTCAAAGAGGGCGGACCGACGTATTGGGATCAGGCTGCGACCCTGTTCGACTGGGGTTTCGCCCTCAACCCGCAGGCCAGCGTCGGCTCGCTCTAG
- Drug Resistance
- Mutations
- Function
- Unknown
- Family
-
Peptidase S11 family
- GO
-
- serine-type D-Ala-D-Ala carboxypeptidase activity GO:0009002 molecular_function
- endopeptidase activity GO:0004175 molecular_function
- InterPro
4RYE
- Name
- Probable penicillin-binding protein DacB2 (D-alanyl-D-alanine carboxypeptidase) (DD-peptidase) (DD-carboxypeptidase) (PBP) (DD-transpeptidase) (Serine-type D-ala-D-ala carboxypeptidase) (D-amino acid...
- Family
- Peptidase S11 family
- Protein Sequence
-
MRKLMTATAALCACAVTVSAGAAWADADVQPAGSVPIPDGPAQTWIVADLDSGQVLAGRDQNVAHPPASTIKVLLALVALDELDLNSTVVADVADTQAECNCVGVKPGRSYTARQLLDGLLLVSGNDAANTLAHMLGGQDVTVAKMNAKAATLGATSTHATTPSGLDGPGGSGASTAHDLVVIFRAAMANPVFAQITAEPSAMFPSDNGEQLIVNQDELLQRYPGAIGGKTGYTNAARKTFVGAAARGGRRLVIAMMYGLVKEGGPTYWDQAATLFDWGFALNPQASVGSL
- Mass
- 29,747 Da
- Length
- 291 Aa
Summary
Rv2911 doesn't seem to be a targeted by any drug.
-
-
Peptidoglycan biosynthesis mtu00550
mtu00550Metabolism; Glycan biosynthesis and metabolism
-
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.