ftsY
- Type
- protein_coding
- Name
- ftsY
- Locus Name
-
Rv2921c
- Product
-
Probable cell division protein FtsY (SRP receptor) (signal recognition particle receptor)
- Functional Category
-
Cell wall and cell processes
- Location
- 3232871..3234139 (- strand)
- Gene Length
- 1268 bp
- Nucleotides
-
GTGTGGGAAGGTTTGTGGATCGCCACGGCGGTCATCGCCGCCCTGGTCGTCATCGCTGCGCTGACCCTGGGGCTGGTGCTCTACCGTCGGCGGCGCATCAGTCTGTCGCCTCGGCCCGAGCGCGGCGTTGTCGACCGCTCAGGCGGTTACACCGCATCGTCTGGCATCACGTTTAGTCAGACGCCGACGACCCAGCCGGCCGAGCGGATCGATACGAGCGGACTGCCCGCCGTGGGCGACGATGCGACCGTCCCTCGCGACGCGCCCAAGCGCACGATCGCCGACGTACACCTTCCCGAGTTTGAGCCAGAACCCCAGGCTCCAGAGGTCCCCGAGGCTGACGCCATCGCGCCGCCCGAAGGTCGATTGGAACGACTGCGCGGACGGCTCGCCAGATCGCAGAATGCCCTCGGGCGCGGCCTGTTGGGACTGATCGGCGGCGGCGACCTGGACGAGGACTCCTGGCAAGACGTCGAGGACACCCTGCTGGTCGCCGACCTGGGACCGGCGGCCACCGCGTCGGTGGTGTCGCAGCTGCGCAGCCGCCTGGCCAGCGGCAACGTGCGTACCGAGGCCGACGCCCGGGCGGTATTGCGTGACGTCCTGATCAACGAACTGCAACCTGGCATGGACCGCTCGATCCGCGCGCTACCGCACGCCGGCCATCCTTCGGTGTTGCTGGTCGTCGGCGTCAACGGCACCGGAAAAACCACCACGGTCGGCAAGTTGGCGCGGGTACTAGTGGCCGACGGCCGACGGGTCGTACTCGGTGCGGCTGACACCTTCCGTGCGGCCGCCGCCGATCAGCTACAGACCTGGGCGGCGCGGGTTGGCGCAGCGGTGGTTCGCGGGCCCGAAGGCGCCGACCCGGCATCGGTGGCGTTCGACGCCGTCGACAAGGGCATCGCCGCCGGCGCAGACGTCGTGCTCATCGATACAGCCGGGCGGCTGCACACCAAGGTTGGCCTGATGGACGAGCTGGACAAGGTCAAGCGCGTGGTGACTCGGCGAGCGTCCGTTGACGAGGTGTTGCTGGTGCTCGATGCCACGATCGGACAGAACGGGTTGGCGCAGGCCAGAGTGTTCGCCGAGGTCGTCGACATCAGCGGCGCGGTGCTCACCAAACTGGACGGAACGGCCAAGGGCGGCATTGTGTTCCGCGTTCAACAGGAACTTGGGGTGCCGGTGAAGCTGGTCGGGCTTGGTGAAGGCCCCGATGACCTGGCGCCTTTCGAACCCGCCGCATTCGTCGACGCCCTGCTCGGCTA
- Drug Resistance
- Mutations
- Function
- Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). {ECO:0000255|HAMAP-Rule:MF_00920}.
- Family
-
GTP-binding SRP family, FtsY subfamily
- GO
-
- signal recognition particle binding GO:0005047 molecular_function
- GTPase activity GO:0003924 molecular_function
- cell wall GO:0005618 cellular_component
- GTP binding GO:0005525 molecular_function
- intrinsic component of plasma membrane GO:0031226 cellular_component
- plasma membrane GO:0005886 cellular_component
- cytoplasm GO:0005737 cellular_component
- membrane GO:0016020 cellular_component
- SRP-dependent cotranslational protein targeting to membrane GO:0006614 biological_process
- protein targeting GO:0006605 biological_process
- InterPro
Summary
- Name
- Signal recognition particle receptor FtsY (SRP receptor)
- Family
- GTP-binding SRP family, FtsY subfamily
- Protein Sequence
-
MWEGLWIATAVIAALVVIAALTLGLVLYRRRRISLSPRPERGVVDRSGGYTASSGITFSQTPTTQPAERIDTSGLPAVGDDATVPRDAPKRTIADVHLPEFEPEPQAPEVPEADAIAPPEGRLERLRGRLARSQNALGRGLLGLIGGGDLDEDSWQDVEDTLLVADLGPAATASVVSQLRSRLASGNVRTEADARAVLRDVLINELQPGMDRSIRALPHAGHPSVLLVVGVNGTGKTTTVGKLARVLVADGRRVVLGAADTFRAAAADQLQTWAARVGAAVVRGPEGADPASVAFDAVDKGIAAGADVVLIDTAGRLHTKVGLMDELDKVKRVVTRRASVDEVLLVLDATIGQNGLAQARVFAEVVDISGAVLTKLDGTAKGGIVFRVQQELGVPVKLVGLGEGPDDLAPFEPAAFVDALLG
- Mass
- 44,031 Da
- Length
- 422 Aa
Rv2921c doesn't seem to be a targeted by any drug.
-
-
Bacterial secretion system mtu03070
mtu03070Environmental Information Processing; Membrane transport
-
-
-
Protein export mtu03060
mtu03060Genetic Information Processing; Folding, sorting and degradation
-
-
-
Quorum sensing mtu02024
mtu02024Cellular Processes; Cellular community - prokaryotes
-
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.