Gene - combatTB X

Rv3193c

Type: protein_coding
Name: Rv3193c
Locus Name: Rv3193c
Product: Probable conserved transmembrane protein
Functional Category: Cell wall and cell processes
Location: 3560194..3563172 (- strand)
Gene Length: 2978 bp
Nucleotides: GTGGGAATGCGGTCCGCCGCAAGGATGCCGAAACTGACACGGCGCAGCCGGATTCTGATCATGATCGCACTGGGTGTGATCGTGCTGCTGCTCGCTGGCCCGCGTTTGATCGACGCTTACGTCGACTGGCTGTGGTTTGGTGAGCTTGGCTACCGCTCAGTGTTCACCACCATGCTGGCTACCCGCATCGTGGTGTGCTTGGTTGCCGGGGTGGTGGTCGGCGGCATCGTGTTCGGCGGGCTCGCCTTGGCCTACCGCACTCGCCCGGTGTTCGTCCCGGATGCCGACAACGATCCGGTTGCACGGTATCGCGCCGTCGTGCTGGCACGCCTGCGGCTAGTCGGCATCGGAATCCCCGCGGCGATCGGCTTGCTGGCCGGCATCGTCGCCCAAAGCTACTGGGCTCGGATCCAGCTGTTCCTGCACGGCGGTGACTTTGGGGTTAGGGATCCGCAGTTCGGGCGGGACCTCGGCTTCTACGCGTTCGAGTTGCCGTTCTACCGGCTGATGCTCAGCTACATGCTCGTTTCGGTATTTCTGGCATTCGTGGCGAATCTGGTGGCGCACTATATCTTCGGTGGCATTCGGCTATCCGGACGCACCGGTGCGCTGAGCCGCTCGGCGCGCGTCCAGTTGGTTAGCCTGGTCGGGGTACTGGTGTTACTTAAAGCCGTTGCTTATTGGCTGGATCGGTATGAGCTGCTGTCGCACACGCGTGGCGGCAAGCCGTTCACCGGTGCCGGGTACACCGATATCAACGCCGTCCTGCCGGCGAAGCTGATTCTGATGGCGATTGCGTTGATTTGCGCGGCCGCAGTGTTCTCGGCGATCGCCCTGCGGGACTTGCGGATTCCGGCGATCGGCCTGGTGTTGTTGCTGCTGTCGTCGCTGATTGTCGGCGCCGGCTGGCCGTTGATCGTCGAGCAAATCAGCGTCAAACCCAACGCTGCGCAAAAAGAGAGCGAATATATCAGCCGAAGTATCACCGCAACTCGGCAAGCCTATGGCCTGACGTCTGATGTGGTGACCTATCGCAATTACAGCGGTGATAGCCCGGCTACCGCGCAACAGGTCGCTGCCGACCGCGCGACTACCTCGAACATCCGGCTACTCGACCCGACAATCGTTAGCCCGGCGTTCACCCAGTTCCAGCAGGGCAAGAACTTCTACTATTTCCCGGACCAGCTGTCGATCGACCGCTACCTCGACCGCAACGGTAACCTGCGCGACTACGTCGTCGCGGCCCGCGAACTCAACCCGGACCGGTTGATCGACAACCAACGGGACTGGATCAACCGGCATACCGTGTACACCCACGGGAACGGGTTCATCGCCTCACCGGCCAACACCGTGCGCGGTATCGCCAACGACCCGAATCAAAATGGCGGTTACCCCGAATTCTTGGTCAACGTCGTCGGGGCCAATGGCACCGTGGTGTCTGATGGGCCGGCGCCACTGGATCAGCCGCGGATCTACTTCGGTCCGGTGATCTCTAACACGTCCGCGGACTATGCGATCGTTGGACGCAATGGCGACGACCGCGAATACGACTACGAAACTAACATCGACACCAAGAGATACACCTACACCGGAAGCGGTGGAGTCCCGCTCGGTGGTTGGTTAGCCCGTAGCGTGTTCGCTGCGAAGTTCGCGGAGCGAAACTTTTTGTTCTCCAATGTGATTGGCTCCAACAGCAAGATCTTGTTCAACCGCGATCCGGCGCAGCGGGTGGAGGCGGTCGCGCCGTGGCTGACGACAGACAGCGCTGTGTATCCCGCGATCGTCAACAAGCGACTGGTGTGGATCGTCGACGGCTACACCACGTTGGACAATTACCCGTACTCCGAGCTCACCTCGCTGTCCTCGGCGACCGCGGACTCCAACGAGGTGGCGTTCAACCGGTTGGTCCCGGACAAGAAGGTTTCCTACATCCGCAATTCGGTGAAGGCCACTGTGGATGCCTACGACGGAACGGTCACGCTGTACCAACAGGACGAAAAGGATCCGGTGCTCAAGGCCTGGATGCAGGTCTTCCCCGGCACGGTAAAGCCTAAGAGCGACATTGCGCCGGAGCTTGCCGAGCACCTGCGGTATCCCGAGGACCTGTTCAAGGTGCAGCGCATGTTGTTGGCCAAATACCACGTCAATGATCCGGTGACGTTCTTCTCCACATCGGATTTCTGGGACGTGCCGCTGGACCCGAATCCGACCGCCAGCAGTTATCAGCCGCCGTATTACATCGTCGCGAAAAACATTGCTAAGGACGATAATTCAGCCTCATATCAGTTGATCAGCGCGATGAACAGATTCAAGCGTGACTATCTGGCCGCCTACATCAGCGCCAGTTCCGATCCCGCGACCTACGGCAATCTCACGGTGTTGACCATCCCAGGCCAGGTCAACGGGCCCAAGTTGGCCAACAACGCGATCACCACCGATCCGGCGGTGTCCCAGGACCTCGGTGTCATCGGACGCGACAACCAAAACCGCATCCGCTGGGGCAACTTGCTCACGCTCCCGGTGGCCCGGGGCGGACTGCTCTACGTCGAACCGGTCTATGCATCCCCGGGAGCCAGCGACGCTGCTTCGTCCTACCCGCGGCTGATCCGGGTGGCGATGATGTACAACGACAAGGTGGGATACGGCCCCACGGTGCGGGATGCGCTCACCGGCTTGTTCGGGCCCGGGGCCGGTGCGACGGCTACCGGGATCGCGCCCACGGAGGCAGCGGTACCACCGAGTCCCGCTGCGAATCCACCGCCGCCTGCCAGTGGACCCCAACCGCCGCCGGTGACTGCGGCGCCCCCGGTTCCCGTCGGGGCGGTCACCTTATCGCCGGCCAAAGTTGCTGCGCTGCAGGAGATCCAGGCTGCCATCGGCGCGGCGCGGGATGCGCAGAAGAAGGGCGACTTCGCCGCCTACGGGTCGGCGCTGCAGCGACTTGATGAGGCCATCACCAAGTTCAACGACGCCGGGTA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

UPF0182 family

GO

cell wall GO:0005618 cellular_component
extracellular region GO:0005576 cellular_component
integral component of plasma membrane GO:0005887 cellular_component
plasma membrane GO:0005886 cellular_component

InterPro

IPR005372

UniProt: P9WFL3
GenBank: Rv3193c
EnsemblBacteria: Rv3193c
Mycobrowser: Rv3193c

Summary

Name: UPF0182 protein Rv3193c
Family: UPF0182 family
Protein Sequence: MGMRSAARMPKLTRRSRILIMIALGVIVLLLAGPRLIDAYVDWLWFGELGYRSVFTTMLATRIVVCLVAGVVVGGIVFGGLALAYRTRPVFVPDADNDPVARYRAVVLARLRLVGIGIPAAIGLLAGIVAQSYWARIQLFLHGGDFGVRDPQFGRDLGFYAFELPFYRLMLSYMLVSVFLAFVANLVAHYIFGGIRLSGRTGALSRSARVQLVSLVGVLVLLKAVAYWLDRYELLSHTRGGKPFTGAGYTDINAVLPAKLILMAIALICAAAVFSAIALRDLRIPAIGLVLLLLSSLIVGAGWPLIVEQISVKPNAAQKESEYISRSITATRQAYGLTSDVVTYRNYSGDSPATAQQVAADRATTSNIRLLDPTIVSPAFTQFQQGKNFYYFPDQLSIDRYLDRNGNLRDYVVAARELNPDRLIDNQRDWINRHTVYTHGNGFIASPANTVRGIANDPNQNGGYPEFLVNVVGANGTVVSDGPAPLDQPRIYFGPVISNTSADYAIVGRNGDDREYDYETNIDTKRYTYTGSGGVPLGGWLARSVFAAKFAERNFLFSNVIGSNSKILFNRDPAQRVEAVAPWLTTDSAVYPAIVNKRLVWIVDGYTTLDNYPYSELTSLSSATADSNEVAFNRLVPDKKVSYIRNSVKATVDAYDGTVTLYQQDEKDPVLKAWMQVFPGTVKPKSDIAPELAEHLRYPEDLFKVQRMLLAKYHVNDPVTFFSTSDFWDVPLDPNPTASSYQPPYYIVAKNIAKDDNSASYQLISAMNRFKRDYLAAYISASSDPATYGNLTVLTIPGQVNGPKLANNAITTDPAVSQDLGVIGRDNQNRIRWGNLLTLPVARGGLLYVEPVYASPGASDAASSYPRLIRVAMMYNDKVGYGPTVRDALTGLFGPGAGATATGIAPTEAAVPPSPAANPPPPASGPQPPPVTAAPPVPVGAVTLSPAKVAALQEIQAAIGAARDAQKKGDFAAYGSALQRLDEAITKFNDAG
Mass: 107,502 Da
Length: 992 Aa

Rv3193c doesn't seem to be a targeted by any drug.

Rv3193c doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.