Gene - combatTB X

Rv3197

Type: protein_coding
Name: Rv3197
Locus Name: Rv3197
Product: Probable conserved ATP-binding protein ABC transporter
Functional Category: Cell wall and cell processes
Location: 3567024..3568367 (+ strand)
Gene Length: 1343 bp
Nucleotides: TGGATGATGGGAGTGTGTCAGATATCAAACGGGGCCGCGCCGCGCGCAATGCGAAGCTGGCCAGCATCCCGGTCGGCTTCGCCGGTCGGGCGGCGCTCGGGCTCGGCAAGCGACTGACCGGTAAGTCAAAAGACGAGGTTACCGCCGAGCTGATGGAGAAGGCCGCCAATCAGTTGTTTACCGTCCTCGGCGAACTCAAGGGTGGCGCGATGAAGGTCGGCCAGGCGCTGTCGGTGATGGAGGCCGCCATTCCCGACGAGTTCGGCGAACCCTACCGGGAAGCACTGACCAAGCTGCAGAAGGACGCCCCACCGCTGCCCGCCAGTAAGGTGCACCGGGTACTCGACGGACAGCTGGGCACCAAATGGCGGGAGCGGTTCAGCTCGTTCAACGACACCCCAGTGGCATCTGCCAGCATCGGCCAGGTGCACAAAGCAATCTGGTCGGACGGCCGAGAAGTGGCCGTCAAGATCCAGTATCCCGGCGCCGACGAGGCGCTGCGCGCGGACCTCAAGACCATGCAGCGCATGGTCGGCGTGCTCAAACAGCTCTCACCCGGCGCCGACGTCCAAGGGGTGGTCGACGAACTGGTTGAACGCACCGAAATGGAACTCGACTACCGGCTGGAGGCCGCCAACCAGCGCGCCTTCGCCAAGGCGTACCACGACCACCCGCGCTTCCAGGTGCCTCACGTCGTGGCAAGCGCACCGAAGGTGGTGATCCAGGAGTGGATCGAAGGTGTGCCGATGGCAGAGATCATCCGTCACGGGACCACCGAGCAGCGTGATCTGATCGGTACGCTGCTCGCCGAGCTCACCTTCGACGCACCACGGCGGCTGGGGTTGATGCACGGCGACGCCCACCCCGGTAATTTCATGCTGCTGCCCGACGGCCGGATGGGCATCATCGACTTCGGTGCCGTGGCACCGATGCCCGGCGGCTTCCCGATAGAGCTCGGGATGACGATTCGACTGGCCCGCGAGAAGAACTACGACCTCCTGTTGCCGACGATGGAGAAGGCCGGGTTGATCCAGCGAGGACGACAGGTGTCGGTTCGCGAGATCGACGAGATGCTGCGCCAATACGTCGAGCCCATCCAGGTCGAGGTCTTCCACTACACCCGCAAGTGGTTACAGAAAATGACCGTCAGTCAGATCGACCGCTCGGTTGCGCAGATCAGAACGGCGCGCCAGATGGACCTGCCGGCCAAGCTCGCGATTCCGATGCGGGTTATCGCATCGGTGGGCGCGATCCTATGCCAGCTGGACGCGCATGTGCCGATCAAGGCCCTGTCGGAGGAGCTGATCCCGGGTTTCGCCGAGCCCGACGCGATCGTCGTCTGA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Unknown

GO

cell wall GO:0005618 cellular_component
ATP binding GO:0005524 molecular_function

InterPro

UniProt: O53343
GenBank: Rv3197
EnsemblBacteria: Rv3197
Mycobrowser: Rv3197

Summary

Name: Probable conserved ATP-binding protein ABC transporter
Family: Unknown
Protein Sequence: MDDGSVSDIKRGRAARNAKLASIPVGFAGRAALGLGKRLTGKSKDEVTAELMEKAANQLFTVLGELKGGAMKVGQALSVMEAAIPDEFGEPYREALTKLQKDAPPLPASKVHRVLDGQLGTKWRERFSSFNDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALRADLKTMQRMVGVLKQLSPGADVQGVVDELVERTEMELDYRLEAANQRAFAKAYHDHPRFQVPHVVASAPKVVIQEWIEGVPMAEIIRHGTTEQRDLIGTLLAELTFDAPRRLGLMHGDAHPGNFMLLPDGRMGIIDFGAVAPMPGGFPIELGMTIRLAREKNYDLLLPTMEKAGLIQRGRQVSVREIDEMLRQYVEPIQVEVFHYTRKWLQKMTVSQIDRSVAQIRTARQMDLPAKLAIPMRVIASVGAILCQLDAHVPIKALSEELIPGFAEPDAIVV
Mass: 49,122 Da
Length: 447 Aa

Rv3197 doesn't seem to be a targeted by any drug.

Rv3197 doesn't seem to be involved in any pathway.

Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target.: Protein Cell. 2018 Nov;9(11):971-975. doi: 10.1007/s13238-017-0502-7.
Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.