Gene - combatTB X

Rv3239c

Type: protein_coding
Name: Rv3239c
Locus Name: Rv3239c
Product: Probable conserved transmembrane transport protein
Functional Category: Cell wall and cell processes
Location: 3614457..3617603 (- strand)
Gene Length: 3146 bp
Nucleotides: ATGCACATTTCGTTGCACGGCGGCAAGGGGTTCGCTAATCTCACCCGTCGTCGCCGACCTTCGTCGGCGTCGGTTCTGCTGGTAGCGGGGTTCGGCGCTTTCCTGGCGTTTCTCGACTCGACAATCGTCAACATCGCGTTCCCGGATATCCAGCGTTCCTTCCCGTCCTACGACATCGGGAGCCTGTCCTGGATTCTGAACGGCTATAACATCGTCTTCGCCGCCTTCATGGTTGCGGCCGGCAGGTTGGCCGATTTGCTGGGCCGCAGACGGACATTCCTGTCCGGTGTGCTGGTGTTCACCATTGCGTCCGGGCTGTGCGCCGTCGCCGGCAGTGTCGAGCAGTTGGTGGCGTTCCGGGTGCTGCAGGGCATCGGGGCTGCGATACTCGTGCCTGCTTCGCTCGCACTGGTCGTTGAGGGCTTCGACGCGGCGCGCCGCGCGCACGCTATCGGCCTGTGGGGTGCGGCGGCAGCGATCGCGGCTGGCCTGGGCCCGCCGATCGGCGGGCTCCTCGTGGAGTGGGCCGGCTGGCGGTGGGTGTTACTGGTCAATGTTCCGCTGGGCATCGTCGCGGCGATCGCCACCAAGCGCATGCTCGTCGAGAGCCGCGCCTCGGGCCGGCGCCGCATGCCTGACTTGCGCGGTGCGCTGCTGCTTGCGGTAACGCTCGGGTTGGTTACCCTCGGTTTGGTCAAGGGGCCGGACTGGGGTTGGTTGAGCGTGGCCACCGTCGGTTCGTTCCTGGCCAGCGTCCTGACCTCGGTTGGGTTCGTGCACAGCTCGCGGTCGCACCCCGCGCCGCTGGTCGAGCCGGCGCTGTTGCGTAGCCGGTCGTTCGTGGCGGGCAACCTGCTCACGCTGGTCGCCGCAGCGGGTTTTTACTGCTATGGCCTTACCCATGTGCTTTACCTCAACTATGTGTGGCACTACTCGCTGCTGAAGGCGGGTTTCGCGATCGCGCCCGCTGCGGTGGTGGCTGCCGTGGTGGCGGCGGCGCTGGGTCGGGTTGCCGGTCGGCATGGGCATCGCGTCATCGTCCTCGTTGGTGCGCTGGTCTGGGCCGGCAGCCTGGTGTGGTATTTGCAGCGTGTCGGGTCCGAGCCGGATTTCCTCCGCGTGTGGCTGCCGGGCCAACTGCTGCAGGGCATCGGTGTCGGCGCGACGTTGCCGGTGTTGAGCAGTGCAGCGCTGGCCGAGGTCGCCAAGGGCGGCAGCTATGCCACCTCGTCGGCGGTCGTTAGCACCACTCGCCAGCTCGGTGCGGTGCTCGGTGTCGCGGTGATGGTGATCTTGATCGGTAAGCCGGAGCACGGTACTGCCGAGGAGGCGTTGCGGCGCGGATGGGCTATGGCTGCCATCTGTTTCATCGCGGTGGCTGTCGCGGCCGCGGTGCTGGGTAGAACCAACCGCAACCCCGTCCAGATGCCGGCGCCGGAGCCCGCGATCGCGCCGCGGTTGGAGCCACCGATTCCCCAGCCGGCGGCCGCGCCGATTGAGCATTGGGCGGCCGGTGACGCCGATCCGCTGGGGAATCTGCCGCTATTTGCCGGCCTGGACGCGGCCACCTTGGCACAGCTCGGGGAGCACGTTGAGGACGTCGAGTTGGAGGCGGGTTGCTATCTCTTCCACGAAGGTGACCCGTCCGATTCGCTTTACGTGATCCGCACGGGTCGCGTGCAGGTGCTGCAGGACAGCATCGTTCTCAAAGAACTGGGTCGCGGGGAGGTTCTCGGGGAGCTTGGGCTACTTATTGACGCGCCCCGGTCCGCGACGGTCCGGGCGTTGCGCGACACCAAGCTAGTGCGGCTCACCAAGGCACAGTTCGACGAGATCGCCGACCATGGTGCGCTGGCGGCGTTGGTAAAGGTGCTGGCAACGCGGCTGCGGGAGGCACCGCCACCGGCGACTGACTCGACGTCGCCTGAGGTGGTCGTTTCGGTGATCGGAGTGAGCGGCGACGCGCCCGTGCCGGCAGTGGCCGCTGGCCTGCTTACCGCGCTGTCGGCGCGGTTGCGTGCCGTTGACCCCGGCCGGGTCGACCGCGACGGCCTTGATCGCGCGGAGCGAGTCGCCGACAAGGTAGTGCTACATGCCGCGGTCGAGGATGCCGGCTGGCGGGACTTCTGCCTGCGCGTCGCCGACCGGATAGTGCTGGTCGCGGGAGATCCCAACCCACAAGCCGCGCGGCTGCCGGCGCGTGCGCGGGGTGCCGACCTCGTGCTGGCCGGTCCGGCCGCCAGCCGGGAGCACCGGCGTCAGTGGGAGGAATTGATCACGCCGCGATCGGTTCATGTGGTTCATTACCGACGCATCTTGGAAAACGTACGCCCGCTCGCCGCACGCATCGCCGGCCGCTCGATCGGTCTAGTCCTCGGCGGCGGTGGCGCGCGCGGCTTTGCGCACCTCGGGGTTCTTGACGAGCTAGAGCGGGTCGGGGTCACCATCGACCGGTTCGCCGGCACCAGCATGGGGGCGGTTATTGCGGTGTTCGGAGCGTGCGGTATGGACGCGGCAACAGCGGACGCCTACGCATACGAGTACTTCATTCGGCACAATCCGCTCAGTGACTACGCGTTTCCGGTCAGGGGGCTAGTCCGTGGTCGACGGACGCTGACCCTATTAGAAGCAGCGTTCGGGGACCGACTGGTCGAGGAGCTGCCAAAGGAGTTCCGTTGCGTTAGCGTCGATTTGCTTGCCCGCCGACCGGTCGTACACCGCCGAGGCCGACTCGTCGATGTCATTGGGTGTTCCCTTCGGCTGCCGGGCATCTATCCGCCCCAGGTCTACAACGGTCGACTGCATGTGGATGGCGGTGTGTTAGACAACCTTCCGGTCTCGACCCGGGCAAGTCCTGATGGCCCATTGATCGCGGTGAGCATCGGCTTAGGTGGTGGCGGGCCGGGCTCGGCTCGACAGGACGGCTCGCCAAAAGTGCCAGGAATCGGCGACACCTTGATGCGCACGATGACAATCGGCAGCCAGCGTGGGGCGGATGCCGCACTCAGTCTTGCGCAGGTCGTTATCAGACCCGACACCGGTGCTGTTGGGCTGCTGGAGTTTCACCAGATCGACGCCGCCCGCGAGGCGGGACGCGTTGCGGCCCGCGAGGCCATGCCGCACATCATGGCACTGTTGAATCGCTG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Major facilitator superfamily

GO

transmembrane transporter activity GO:0022857 molecular_function
phosphatidylcholine metabolic process GO:0046470 biological_process
plasma membrane GO:0005886 cellular_component
lysophospholipase activity GO:0004622 molecular_function
integral component of membrane GO:0016021 cellular_component
lipid catabolic process GO:0016042 biological_process

InterPro

UniProt: O05884
GenBank: Rv3239c
EnsemblBacteria: Rv3239c
Mycobrowser: Rv3239c

Summary

Name: Probable conserved transmembrane transport protein
Family: Major facilitator superfamily
Protein Sequence: MHISLHGGKGFANLTRRRRPSSASVLLVAGFGAFLAFLDSTIVNIAFPDIQRSFPSYDIGSLSWILNGYNIVFAAFMVAAGRLADLLGRRRTFLSGVLVFTIASGLCAVAGSVEQLVAFRVLQGIGAAILVPASLALVVEGFDAARRAHAIGLWGAAAAIAAGLGPPIGGLLVEWAGWRWVLLVNVPLGIVAAIATKRMLVESRASGRRRMPDLRGALLLAVTLGLVTLGLVKGPDWGWLSVATVGSFLASVLTSVGFVHSSRSHPAPLVEPALLRSRSFVAGNLLTLVAAAGFYCYGLTHVLYLNYVWHYSLLKAGFAIAPAAVVAAVVAAALGRVAGRHGHRVIVLVGALVWAGSLVWYLQRVGSEPDFLRVWLPGQLLQGIGVGATLPVLSSAALAEVAKGGSYATSSAVVSTTRQLGAVLGVAVMVILIGKPEHGTAEEALRRGWAMAAICFIAVAVAAAVLGRTNRNPVQMPAPEPAIAPRLEPPIPQPAAAPIEHWAAGDADPLGNLPLFAGLDAATLAQLGEHVEDVELEAGCYLFHEGDPSDSLYVIRTGRVQVLQDSIVLKELGRGEVLGELGLLIDAPRSATVRALRDTKLVRLTKAQFDEIADHGALAALVKVLATRLREAPPPATDSTSPEVVVSVIGVSGDAPVPAVAAGLLTALSARLRAVDPGRVDRDGLDRAERVADKVVLHAAVEDAGWRDFCLRVADRIVLVAGDPNPQAARLPARARGADLVLAGPAASREHRRQWEELITPRSVHVVHYRRILENVRPLAARIAGRSIGLVLGGGGARGFAHLGVLDELERVGVTIDRFAGTSMGAVIAVFGACGMDAATADAYAYEYFIRHNPLSDYAFPVRGLVRGRRTLTLLEAAFGDRLVEELPKEFRCVSVDLLARRPVVHRRGRLVDVIGCSLRLPGIYPPQVYNGRLHVDGGVLDNLPVSTRASPDGPLIAVSIGLGGGGPGSARQDGSPKVPGIGDTLMRTMTIGSQRGADAALSLAQVVIRPDTGAVGLLEFHQIDAAREAGRVAAREAMPHIMALLNR
Mass: 110,199 Da
Length: 1048 Aa

Rv3239c doesn't seem to be a targeted by any drug.

Rv3239c doesn't seem to be involved in any pathway.

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.