Gene - combatTB X

Type: protein_coding
Name: Rv3249c
Locus Name: Rv3249c
Product: Possible transcriptional regulatory protein (probably TetR-family)
Functional Category: Regulatory proteins
Location: 3629752..3630387 (- strand)
Gene Length: 635 bp
Nucleotides: GTGAGCACTCCAAGCGCTACTGTCGCGCCTGTGAAGCGGATACCCTATGCCGAGGCCTCGCGGGCCCTGTTGCGGGATTCGGTGCTGGATGCGATGCGGGATCTGCTGCTGACCCGCGACTGGTCCGCCATCACGCTGTCCGACGTGGCCCGCGCGGCGGGCATCAGCCGGCAGACCATCTACAACGAATTCGGTTCCCGGCAAGGCCTGGCGCAGGGATACGCGCTGCGCCTGGCCGACCGATTAGTGGACAACGTCCATGCATCGTTGGACGCCAACGTCGGCAACTTTTACGAAGCGTTCCTGCAGGGCTTTCGGTCGTTCTTCGCCGAGTCGGCGGCAGATCCGTTGGTCATCTCGCTGTTGACCGGTGTCGCCAAGCCCGATCTGCTGCAACTGATCACCACCGACAGCGCGCCGATCATCACCCGCGCGTCGGCCCGGCTGGCGCCGGCCTTCACCGATACCTGGGTGGCCACCACCGATAACGACGCCAATGTGCTCTCGCGTGCGATCGTGCGGCTGTGCTTGAGCTACGTGTCGATGCCGCCCGAGGCCGACCATGATGTCGCAGCGGACCTAGCACGGCTAATAACGCCGTTCGCGGAGCGTCACGGTGTGATCAATGTCCCCTG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Unknown

GO

InterPro

Summary

Name: Possible transcriptional regulatory protein (Probably TetR-family)
Family: Unknown
Protein Sequence: MSTPSATVAPVKRIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIYNEFGSRQGLAQGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFFAESAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLAPAFTDTWVATTDNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFAERHGVINVP
Mass: 22,800 Da
Length: 211 Aa

Rv3249c doesn't seem to be a targeted by any drug.

Rv3249c doesn't seem to be involved in any pathway.

Structural Basis for the Regulation of the MmpL Transporters of Mycobacterium tuberculosis.: J Biol Chem. 2015 Nov 20;290(47):28559-74. doi: 10.1074/jbc.M115.683797. Epub 2015 Sep 22.
Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.