Gene - combatTB X

Rv3253c

Type: protein_coding
Name: Rv3253c
Locus Name: Rv3253c
Product: Possible cationic amino acid transport integral membrane protein
Functional Category: Cell wall and cell processes
Location: 3632097..3633584 (- strand)
Gene Length: 1487 bp
Nucleotides: ATGGCCGGTCGACGGCGCATGAAGTCGGTAGAACAGTCAATCGCCGACACCGACGAGCCCACCACTCGGCTGCGCAAGGACCTCACCTGGTGGGACCTGGTTGTTTTCGGCGTCTCGGTGGTGATTGGCGCCGGAATATTCACGGTTACCGCGTCGACCGCTGGCGATATCACCGGCCCGGCCATCTGGATATCGTTTCTGATCGCGGCGGCGACCTGTGCGCTGGCCGCGCTGTGCTACGCCGAGTTCGCCTCGACGCTGCCGGTGGCCGGCAGCGCCTATACCTTCTCTTATGCCACCTTCGGGGAGTTCTTGGCCTGGGTGATCGGCTGGAATCTGGTGCTGGAACTGGCGATGGGTGCGGCCGTGGTCGCCAAAGGCTGGTCCAGCTACTTGGGCACCGTGTTCGGATTCGGTAATGGCACAGGCCATCTCGGATCGCTGCAGCTCGACTGGGGTGCGCTCGTGATCGTCACGTTGGTGGCGACCCTGATCGCGTTGGGCACCAAATTGTCGTCGAGATTTTCCGCGGTGGTCACCGCAATCAAGGTGTCGGTGGTCGTCTTGGTGGTGGTCGTCGGTGCCTTCTACATCAGGGCCGCCAACTACTCGCCGTTCATTCCCGAGCCCGAAGTCCAGCACCACGGCGGCGGGCTCGATCAATCCGTCTTCTCGTTGCTGACCGGAGCCCAAGGCAGCCACTACGGATGGTACGGCGTGCTGGCCGGGGCATCGATCGTGTTCTTCGCGTTTATCGGGTTTGACATCGTGGCCACCATGGCCGAGGAGACCAAGCGTCCTCAACGAGACGTCCCTCGAGGGATTCTCGCGTCGCTGGGGGTCGTGACCCTTCTCTACGTCGCGGTATCGGTGGTGCTGTCGGGCATGGTTCCATACACCCAACTGCGGACCGTACCGGGCCGCGGGCCGGCAAATCTGGCCACCGCGTTCCAGGCCAACGGGGTGTACTGGGCCAGCGGCATCATCTCCGTCGGCGCGCTGGCCGGGCTTACCACGGTGGTGATGGTGTTGATGCTCGGGCAATGCCGCGTGCTGTTCGCCATGGCGCGCGACGGCTTGGTGCCGCGGCAATTGGCCAAGACCGGTTCGCGCGGCACCCCGGTCCGGGTCACGGTGCTGGTCGCGGTGTTGGTGGCCACGACGGCGTCGGTGTTTCCGATCACCAAGCTTGAGGAGATGGTCAACGTCGGGACACTGTTCGCGTTCATCCTCGTCTCGGCCGGAGTGGTCGTGCTGCGCCGGACCCGACCCGACCTTCAGCGGGGGTTCACAGCTCCGTGGGTGCCGTTACTTCCGATCGCCGCAGTGTGCGCGTGCCTGTGGCTGATGCTGAACCTCACCGCGTTGACTTGGATCCGGTTCGGGATCTGGCTGGTGGCCGGAACCGCGATTTATGTCGGCTACGGGCGCCGGCACTCGGCGCAGGGCCTTCGGCAAGCTCGAGAGAGCGCGACCCGGAGGTGTTG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Unknown

GO

transmembrane transporter activity GO:0022857 molecular_function
extracellular region GO:0005576 cellular_component
integral component of membrane GO:0016021 cellular_component

InterPro

IPR002293

UniProt: O05896
GenBank: Rv3253c
EnsemblBacteria: Rv3253c
Mycobrowser: Rv3253c

Summary

Name: Possible cationic amino acid transport integral membrane protein
Family: Unknown
Protein Sequence: MAGRRRMKSVEQSIADTDEPTTRLRKDLTWWDLVVFGVSVVIGAGIFTVTASTAGDITGPAIWISFLIAAATCALAALCYAEFASTLPVAGSAYTFSYATFGEFLAWVIGWNLVLELAMGAAVVAKGWSSYLGTVFGFGNGTGHLGSLQLDWGALVIVTLVATLIALGTKLSSRFSAVVTAIKVSVVVLVVVVGAFYIRAANYSPFIPEPEVQHHGGGLDQSVFSLLTGAQGSHYGWYGVLAGASIVFFAFIGFDIVATMAEETKRPQRDVPRGILASLGVVTLLYVAVSVVLSGMVPYTQLRTVPGRGPANLATAFQANGVYWASGIISVGALAGLTTVVMVLMLGQCRVLFAMARDGLVPRQLAKTGSRGTPVRVTVLVAVLVATTASVFPITKLEEMVNVGTLFAFILVSAGVVVLRRTRPDLQRGFTAPWVPLLPIAAVCACLWLMLNLTALTWIRFGIWLVAGTAIYVGYGRRHSAQGLRQARESATRRC
Mass: 52,520 Da
Length: 495 Aa

Rv3253c doesn't seem to be a targeted by any drug.

Rv3253c doesn't seem to be involved in any pathway.

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.