Gene - combatTB X

Rv3327

Type: protein_coding
Name: Rv3327
Locus Name: Rv3327
Product: Probable transposase fusion protein
Functional Category: Insertion seqs and phages
Location: 3711749..3713461 (+ strand)
Gene Length: 1712 bp
Nucleotides: TGGTTGTTGTTGGAACCGATGCGCACAAGTACAGCCACACCTTTGTGGCCACCGACGAAGTGGGTCGCCAACTCGGTGAGAAGACCGTCAAGGCCACCACGGCCGGGCACGCCACAGCCATCATGTGGGCCCGTGAACAGTTCGGCCTCGAGCTGATCTGGGGCATCGAGGACTGCCGCAACATGTCGGCGCGTCTGGAGCGTGACCTACTGGCGGCCGGCCAGCAGGTGGTGCGGGTACCCACCAAGCTGATGGCCCAGACCCGCAAGTCGGCGCGCAGTCGGGGCAAGTCGGATCCGATCGATGCGCTGGCGGTGGCGCGGGCGGTGCTGCGTGAAACCGACCTACCCCTGGCCACCCACGACGAGACGTCGCGGGAGTTGAAGTTGTTGACTGACCGTCGAGATGTCCTTGTGGCCCAACGCACGTCGGCGATCAACCGGTTGCGCTGGCTCGTCCATGAACTCGATCCCGAGCGGGCACCGGCAGCACGCTCGCTCGATGCCGCCAAGCACCAGCAGGCCCTGCGGACCTGGCTGGACACCCAGCCAGGATTGGTCGCCGAACTCGCGCGCGCCGAGCTGACCGACATCATCCGGCTCACCGGCGAGATCAACACCCTAGCCCAGCGCATCAGCGCCCGAGTCCACCAGGTCGCCCCCGCACTGCTGGAAATCCCTGGCTGCGCGGAGCTGACTGCAGCCAAAATCGTCGGCGAAGCCGCCGGAGTGACCCGGTTCAAAAGCGAAGCCGCCTTCGCCTGCCATGCCGCAGTGGCTCCCATCCCGGTGTGGTCGGGCAACACCGCCGGCCAGATGCGGCTCAGCCGCTCGGGCAACCGCCAGCTCAACGCCGCCCTACACCGCATCGCACTGACCCAAATCCGGATGACCGACAGCCGGGGCCAGGCCTACTACCAAAGGCTGCAAGACGCCGGGAAAACCAAACGCGCAGCACTACGCTGCCTCAAACGCCGCCTAGCCCGCACCGTCTTCCAGGCCCTGCGCACCGTCCACCAGCCCAGCTCCGAACACACCCAACCCGCGGCCGCTTGCCATAGGAGCTATTGCTCGTCACACCTCGGCGAGCCACCTCGTCTAACGGATATGACACAGAAAACCCGCATCCAGCCCCTACCTCCCAAGCGAGCCGGCCTGTTGATCCGCGCACTGTATCGGATCGCCAAGCGGCGCTTCGGCGAAGTTCCCGAGCCGTTCACGGTCACCGCACATCATCGGCGGCTGCTGATCGCCAATGTGGTGCACGAAGCCCTGCTGCAGCGAGCGTCGCGGAAGCTACCGCCCAGCGTCCGTGAGCTGGCGGTGTTTTGGACCGCCCGCAGCATCGGCTGCTCGTGGTGCGTGGACTTCGGAGCCATGCTGCAGCGCCTGGACGGGCTGGACGTGGACAGGCTCACGGACATCGACAATTACGCCACCTCATCGAAATTCAGCGACGACGAACGCGCCGCCATCGCCTACGCCGAGGCGATGACCGCAGACCCGCATTCGGTGACCGACGAGCAGGTGGCCGACCTGCGGGCCCGCTTCGGCGAGGCCGGCGTGATCGAGCTGACTTACCAGATCGGCGTGGAGAACATGCGAGCCCGGATGAATTCGGCGCTGGGCATCACCGAGCAAGGCTTCAATTCCGGTGATGCCTGCCGCGTCCCGTGGGCTGCGCCCGACGTTCCTTCAGCGGAGAGCCGGTGA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Unknown

GO

DNA binding GO:0003677 molecular_function
transposition, DNA-mediated GO:0006313 biological_process
transposase activity GO:0004803 molecular_function

InterPro

UniProt: O53377
GenBank: Rv3327
EnsemblBacteria: Rv3327
Mycobrowser: Rv3327

Summary

Name: Probable transposase fusion protein
Family: Unknown
Protein Sequence: MVVVGTDAHKYSHTFVATDEVGRQLGEKTVKATTAGHATAIMWAREQFGLELIWGIEDCRNMSARLERDLLAAGQQVVRVPTKLMAQTRKSARSRGKSDPIDALAVARAVLRETDLPLATHDETSRELKLLTDRRDVLVAQRTSAINRLRWLVHELDPERAPAARSLDAAKHQQALRTWLDTQPGLVAELARAELTDIIRLTGEINTLAQRISARVHQVAPALLEIPGCAELTAAKIVGEAAGVTRFKSEAAFACHAAVAPIPVWSGNTAGQMRLSRSGNRQLNAALHRIALTQIRMTDSRGQAYYQRLQDAGKTKRAALRCLKRRLARTVFQALRTVHQPSSEHTQPAAACHRSYCSSHLGEPPRLTDMTQKTRIQPLPPKRAGLLIRALYRIAKRRFGEVPEPFTVTAHHRRLLIANVVHEALLQRASRKLPPSVRELAVFWTARSIGCSWCVDFGAMLQRLDGLDVDRLTDIDNYATSSKFSDDERAAIAYAEAMTADPHSVTDEQVADLRARFGEAGVIELTYQIGVENMRARMNSALGITEQGFNSGDACRVPWAAPDVPSAESR
Mass: 62,961 Da
Length: 570 Aa

Rv3327 doesn't seem to be a targeted by any drug.

Rv3327 doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.