Gene - combatTB X

Rv3401

Type: protein_coding
Name: Rv3401
Locus Name: Rv3401
Product: Conserved protein
Functional Category: Intermediary metabolism and respiration
Location: 3818042..3820402 (+ strand)
Gene Length: 2360 bp
Nucleotides: TGATCACCGAGGACGCCTTCCCCGTCGAACCGTGGCAGGTCCGCGAGACCAAGCTCAACCTGAACCTGCTGGCCCAGTCCGAATCCCTATTCGCCTTGTCCAACGGGCACATTGGATTACGCGGCAACCTCGACGAGGGCGAACCCTTCGGACTGCCGGGCACCTACCTGAACTCTTTCTACGAAATCCGGCCGCTGCCGTACGCCGAGGCCGGTTATGGATATCCGGAGGCCGGCCAGACCGTTGTCGACGTCACCAACGGCAAGATCTTTCGCCTGTTGGTCGGCGACGAGCCGTTCGACGTCCGGTATGGCGAATTGATCTCCCACGAACGGATCCTCGACCTGCGCGCCGGGACGCTGACCCGCCGCGCGCACTGGCGCTCACCGGCGGGCAAGCAAGTCAAAGTGACGTCCACCCGGCTGGTGTCGCTGGCCCACCGCAGCGTCGCGGCGATCGAGTACGTCGTCGAGGCAATCGAGGAATTCGTTCGCGTGACCGTGCAGTCCGAACTCGTCACCAACGAGGACGTACCGGAGACCTCGGCCGACCCGCGGGTGTCGGCCATCCTGGACAGGCCGCTACAGGCCGTCGAGCACGAACGCACCGAGCGGGGTGCACTTCTCATGCACCGCACCCGAGCCAGCGCGCTGATGATGGCCGCAGGGATGGAACACGAGGTCGAGGTTCCCGGGCGGGTCGAGATCACCACCGACGCCCGCCCGGACCTGGCCCGAACCACCGTGATCTGCGGGCTGCGCCCGGGACAGAAGCTGCGCATCGTCAAATACCTGGCCTATGGCTGGTCCAGCCTGCGCTCCCGCCCGGCGCTGCGCGACCAGGCCGCCGGCGCGCTGCACGGTGCCCGCTACAGCGGCTGGCAGGGGCTGCTGGACGCGCAACGCGCCTACCTCGACGACTTCTGGGACAGCGCGGACGTGGAGGTCGAGGGCGACCCGGAATGTCAGCAAGCGGTGCGTTTCGGGTTATTTCACCTGTTGCAGGCCAGCGCGCGCGCCGAACGCCGCGCGATCCCCAGCAAGGGGCTCACCGGAACCGGGTATGACGGCCACGCCTTTTGGGACACCGAAGGTTTCGTGCTACCGGTGCTCACCTACACCGCACCGCATGCGGTCGCCGACGCGCTGCGGTGGCGGGCGTCGACGTTGGACCTGGCCAAGGAGCGGGCGGCCGAGCTCGGCCTGGAAGGTGCCGCCTTTCCCTGGCGGACCATCCGCGGACAGGAGTCCTCGGCCTACTGGCCGGCCGGCACGGCGGCCTGGCACATCAACGCCGACATCGCGATGGCGTTCGAGCGGTACCGCATCGTCACCGGCGACGGTTCGCTGGAGGAGGAATGCGGCCTTGCGGTGCTGATCGAGACCGCCCGGCTGTGGCTCTCGCTCGGGCACCACGACCGCCACGGCGTCTGGCACCTCGACGGGGTCACCGGTCCCGACGAGTACACGGCGGTCGTCCGCGACAACGTGTTCACGAATCTGATGGCGGCGCACAATCTGCACACCGCCGCCGATGCTTGCTTGCGCCACCCCGAGGCGGCGGAGGCCATGGGTGTCACCACCGAGGAGATGGCCGCCTGGCGCGACGCGGCCGACGCCGCCAACATTCCCTACGACGAGGAACTCGGTGTCCACCAGCAGTGTGAAGGGTTCACCACCCTTGCGGAGTGGGATTTCGAAGCCAACACCACTTATCCGTTGCTACTGCACGAGGCCTACGTGCGCTTGTATCCCGCACAGGTGATCAAGCAGGCCGACCTGGTGCTGGCGATGCAGTGGCAGAGTCACGCGTTCACGCCCGAGCAGAAGGCGCGCAACGTCGACTACTACGAACGGCGCATGGTGCGCGACTCGTCGTTGTCGGCCTGCACTCAGGCGGTGATGTGCGCCGAGGTCGGCCATCTCGAGTTGGCCCACGACTATGCCTACGAAGCCGCCCTGATCGACCTGCGCGACCTGCACCGCAACACCCGTGACGGCCTACACATGGCTTCGCTGGCCGGAGCCTGGACGGCGCTGGTCGTAGGCTTCGGCGGCCTACGCGACGACGAGGGCATCCTGTCCATCGATCCGCAGCTGCCCGACGGCATCTCGCGGCTGCGGTTCCGGCTGCGATGGCGCGGCTTCCGGCTGATCGTCGACGCCAACCACACCGACGTCACCTTCATCCTTGGCGACGGTCCCGGCACCCAGCTGACCATGCGCCACGCCGGCCAAGATCTGACGCTGCACACGGACACACCGTCCACCATCGCCGTGCGCACCCGTAAGCCGCTGCTGCCGCCACCACCGCAGCCGCCAGGCCGCGAGCCAGTGCACCGCCGGGCTTTAGCCCGGTGA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Glycosyl hydrolase 65 family

GO

carbohydrate binding GO:0030246 molecular_function
carbohydrate metabolic process GO:0005975 biological_process
plasma membrane GO:0005886 cellular_component
hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 molecular_function

InterPro

UniProt: P9WN13
GenBank: Rv3401
EnsemblBacteria: Rv3401
Mycobrowser: Rv3401

Summary

Name: Uncharacterized glycosyl hydrolase Rv3401 (EC 3.2.1.-)
Family: Glycosyl hydrolase 65 family
Protein Sequence: MITEDAFPVEPWQVRETKLNLNLLAQSESLFALSNGHIGLRGNLDEGEPFGLPGTYLNSFYEIRPLPYAEAGYGYPEAGQTVVDVTNGKIFRLLVGDEPFDVRYGELISHERILDLRAGTLTRRAHWRSPAGKQVKVTSTRLVSLAHRSVAAIEYVVEAIEEFVRVTVQSELVTNEDVPETSADPRVSAILDRPLQAVEHERTERGALLMHRTRASALMMAAGMEHEVEVPGRVEITTDARPDLARTTVICGLRPGQKLRIVKYLAYGWSSLRSRPALRDQAAGALHGARYSGWQGLLDAQRAYLDDFWDSADVEVEGDPECQQAVRFGLFHLLQASARAERRAIPSKGLTGTGYDGHAFWDTEGFVLPVLTYTAPHAVADALRWRASTLDLAKERAAELGLEGAAFPWRTIRGQESSAYWPAGTAAWHINADIAMAFERYRIVTGDGSLEEECGLAVLIETARLWLSLGHHDRHGVWHLDGVTGPDEYTAVVRDNVFTNLMAAHNLHTAADACLRHPEAAEAMGVTTEEMAAWRDAADAANIPYDEELGVHQQCEGFTTLAEWDFEANTTYPLLLHEAYVRLYPAQVIKQADLVLAMQWQSHAFTPEQKARNVDYYERRMVRDSSLSACTQAVMCAEVGHLELAHDYAYEAALIDLRDLHRNTRDGLHMASLAGAWTALVVGFGGLRDDEGILSIDPQLPDGISRLRFRLRWRGFRLIVDANHTDVTFILGDGPGTQLTMRHAGQDLTLHTDTPSTIAVRTRKPLLPPPPQPPGREPVHRRALAR
Mass: 87,316 Da
Length: 786 Aa

Rv3401 doesn't seem to be a targeted by any drug.

Rv3401 doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.