Gene - combatTB X

Rv3402c

Type: protein_coding
Name: Rv3402c
Locus Name: Rv3402c
Product: Conserved hypothetical protein
Functional Category: Cell wall and cell processes
Location: 3820653..3821891 (- strand)
Gene Length: 1238 bp
Nucleotides: ATGAAGATCCGAACGTTATCCGGCTCGGTGCTGGAGCCGCCGTCCGCAGTACGCGCGACCCCAGGCACGTCCATGTTAAAACTCGAGCCGGGTGGCTCGACGATCCCCAAGATCCCCTTCATCCGCCCGAGCTTTCCCGGGCCAGCCGAGCTCGCCGAGGACTTCGTACAGATCGCCCAGGCTAACTGGTACACGAACTTCGGTCCGAACGAGCGGCGGTTTGCCCGCGCCCTGCGCGACTATCTGGGACCTCATCTGCACGTTGCTACCCTCGCCAACGGCACCCTGGCACTCCTCGCGGCGCTCCACGTCAGTTTCGGCGCCGGTACGCGGGACCGCTACCTGCTGATGCCGTCGTTCACGTTCGTCGGCGTGGCTCAGGCTGCGCTATGGACTGGGTACCGTCCCTGGTTCATCGACATCGACGCCAACACATGGCAGCCATGCGTCCACTCCGCCCGCGCCGTCATCGAACGCTTCCGCGACCGGATCGCCGGCATCCTGCTGGCCAATGTGTTCGGCGTCGGCAATCCCCAGATCAGCGTCTGGGAGGAGCTCGCCGCCGAATGGGAGCTACCGATTGTGCTCGACTCGGCGGCCGGCTTCGGCTCCACGTACGCCGACGGCGAGCGCCTCGGTGGACGCGGTGCATGCGAGATCTTCTCCTTCCATGCGACCAAGCCGTTCGCGGTTGGTGAGGGCGGCGCTCTGGTTTCTCGCGATCCACGGCTCGTCGAGCACGCATACAAGTTCCAGAACTTCGGCTTGGTGCAAACACGCGAGTCCATCCAGCTCGGAATGAACGGCAAGCTGTCGGAGATCAGCGCCGCTATTGGCCTACGCCAACTAGTCGGGCTTGATCGCCGCCTGGCAAGTCGCCGCAAGGTCCTCGAGTGCTATCGCACCGGTATGGCCGACGCGGGTGTGCGTTTCCAGGACAACGCCAATGTTGCGTCGCTCTGTTTCGCGAGCGCTTGCTGCACGTCCGCCGACCACAAGGCCGCGGTTCTGGGTAGCCTGCGTAGGCACGCGATCGAGGCGCGCGACTACTACAACCCACCGCAGCACCGACATCCGTACTTTGTGACGAATGCCGAGTTAGTCGAGTCGACCGATCTAGCCGTCACGGCGGACATTTGCTCGCGAATCGTGTCGCTGCCAGTCCACGACCACATGGCCCCGGATGACGTTGCCCGGGTCGTCGCCGCCGTGCAGGAAGCGGAGGTGCGCGGTGAATG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

DegT/DnrJ/EryC1 family

GO

cellular response to iron ion starvation GO:0010106 biological_process
polysaccharide biosynthetic process GO:0000271 biological_process
extracellular region GO:0005576 cellular_component
response to host immune response GO:0052572 biological_process
pyridoxal phosphate binding GO:0030170 molecular_function
transaminase activity GO:0008483 molecular_function

InterPro

UniProt: P9WGJ7
GenBank: Rv3402c
EnsemblBacteria: Rv3402c
Mycobrowser: Rv3402c

Summary

Name: Protein Rv3402c
Family: DegT/DnrJ/EryC1 family
Protein Sequence: MKIRTLSGSVLEPPSAVRATPGTSMLKLEPGGSTIPKIPFIRPSFPGPAELAEDFVQIAQANWYTNFGPNERRFARALRDYLGPHLHVATLANGTLALLAALHVSFGAGTRDRYLLMPSFTFVGVAQAALWTGYRPWFIDIDANTWQPCVHSARAVIERFRDRIAGILLANVFGVGNPQISVWEELAAEWELPIVLDSAAGFGSTYADGERLGGRGACEIFSFHATKPFAVGEGGALVSRDPRLVEHAYKFQNFGLVQTRESIQLGMNGKLSEISAAIGLRQLVGLDRRLASRRKVLECYRTGMADAGVRFQDNANVASLCFASACCTSADHKAAVLGSLRRHAIEARDYYNPPQHRHPYFVTNAELVESTDLAVTADICSRIVSLPVHDHMAPDDVARVVAAVQEAEVRGE
Mass: 44,897 Da
Length: 412 Aa

Rv3402c doesn't seem to be a targeted by any drug.

Rv3402c doesn't seem to be involved in any pathway.

The Mycobacterium tuberculosis IdeR is a dual functional regulator that controls transcription of genes involved in iron acquisition, iron storage and survival in macrophages.: Mol Microbiol. 2001 Nov;42(3):851-65.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.