eccD4
- Type
- protein_coding
- Name
- eccD4
- Locus Name
-
Rv3448
- Product
-
ESX conserved component EccD4. ESX-4 type VII secretion system protein. Probable integral membrane protein.
- Functional Category
-
Cell wall and cell processes
- Location
- 3868352..3869755 (+ strand)
- Gene Length
- 1403 bp
- Nucleotides
-
TGCCTACGTCTGATCCGGGACTGCGCCGGGTCACCGTACATGCCGGCGCCCAGGCCGTCGACCTGACCTTGCCCGCCGCGGTGCCCGTCGCGACTCTGATCCCGTCGATCGTCGACATCCTGGGTGACCGTGGCGCCAGCCCGGCGACGGCGGCGCGCTACCAGCTGTCTGCCCTGGGGGCGCCAGCTCTGCCAAACGCAACGACATTGGCGCAATGCGGTATCCGCGACGGCGCCGTCCTGGTCTTGCATAAGTCCAGCGCCCAGCCGCCCACCCCCCGCTGTGACGATGTGGCCGAAGCGGTGGCGGCGGCGCTTGACACCACAGCCCGGCCCCAATGCCAGCGCACGACCCGGCTCAGCGGTGCGCTGGCGGCAAGCTGCATCACCGCCGGCGGCGGCCTGATGCTGGTTCGAAACGCCCTCGGCACCAACGTAACCCGCTACTCCGACGCCACGGCCGGAGTTGTAGCGGCGGCCGGCTTGGCTGCCTTGCTGTTTGCGGTGATTGCATGCCGGACATATCGGGACCCGATCGCCGGCCTCACGTTGAGCGTTATCGCCACCATATTCGGTGCTGTTGCCGGCCTACTGGCGGTGCCCGGGGTCCCCGGTGTCCATAGCGTGCTAGTTGCCGCGATGGCGGCGGCCGCCACGTCGGTGCTGGCAATGCGCATAACGGGTTGTGGGGGTATCACGTTGACCGCGGTGGCGTGCTGCGCGGTAGTCGTCGCGGCCGCTACGCTGGTCGGCGCGATCACTGCGGCCCCGGTGCCTGCCATCGGTTCGCTGGCCACGCTGGCATCCTTTGGTCTGTTAGAGGTATCCGCGCGGATGGCAGTCCTGTTGGCGGGGTTGTCGCCACGATTGCCGCCCGCGCTGAACCCCGACGACGCCGATGCCCTGCCCACCACGGATCGGCTGACCACCCGAGCGAACCGTGCAGATGCTTGGTTGACGAGCCTGCTGGCGGCCTTCGCGGCCTCGGCGACCATCGGTGCCATCGGAACCGCCGTCGCAACCCACGGCATCCACAGGTCCAGCATGGGCGGTATCGCGTTGGCCGCCGTCACCGGTGCGCTGCTGCTGCTACGAGCACGTTCAGCAGACACCAGAAGGTCACTGGTGTTTGCCATCTGTGGAATCACCACCGTTGCAACGGCATTTACCGTCGCCGCGGATCGGGCTCTGGAACACGGGCCGTGGATTGCCGCGCTGACCGCCATGCTGGCCGCCGTGGCAATGTTTTTGGGCTTCGTCGCTCCCGCGTTGTCGCTCTCGCCCGTCACGTACCGCACCATCGAATTGCTGGAGTGTCTGGCGCTGATCGCAATGGTTCCATTGACCGCTTGGCTATGCGGCGCCTACAGCGCCGTTCGCCACCTCGACCTGACATGGACATGA
- Drug Resistance
- Mutations
- Function
- Unknown
- Family
-
EccD/Snm4 family
- GO
-
- cell wall GO:0005618 cellular_component
- plasma membrane GO:0005886 cellular_component
- integral component of membrane GO:0016021 cellular_component
- InterPro
Summary
- Name
- ESX-4 secretion system protein eccD4 (ESX conserved component D4) (Type VII secretion system protein eccD4) (T7SS protein eccD4)
- Family
- EccD/Snm4 family
- Protein Sequence
-
MPTSDPGLRRVTVHAGAQAVDLTLPAAVPVATLIPSIVDILGDRGASPATAARYQLSALGAPALPNATTLAQCGIRDGAVLVLHKSSAQPPTPRCDDVAEAVAAALDTTARPQCQRTTRLSGALAASCITAGGGLMLVRNALGTNVTRYSDATAGVVAAAGLAALLFAVIACRTYRDPIAGLTLSVIATIFGAVAGLLAVPGVPGVHSVLVAAMAAAATSVLAMRITGCGGITLTAVACCAVVVAAATLVGAITAAPVPAIGSLATLASFGLLEVSARMAVLLAGLSPRLPPALNPDDADALPTTDRLTTRANRADAWLTSLLAAFAASATIGAIGTAVATHGIHRSSMGGIALAAVTGALLLLRARSADTRRSLVFAICGITTVATAFTVAADRALEHGPWIAALTAMLAAVAMFLGFVAPALSLSPVTYRTIELLECLALIAMVPLTAWLCGAYSAVRHLDLTWT
- Mass
- 46,731 Da
- Length
- 467 Aa
Rv3448 doesn't seem to be a targeted by any drug.
Rv3448 doesn't seem to be involved in any pathway.
- Systematic genetic nomenclature for type VII secretion systems.
- PLoS Pathog. 2009 Oct;5(10):e1000507. doi: 10.1371/journal.ppat.1000507. Epub 2009 Oct 30.
- targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis.
- BMC Syst Biol. 2008 Dec 19;2:109. doi: 10.1186/1752-0509-2-109.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.