rpsD
- Type
- protein_coding
- Name
- rpsD
- Locus Name
-
Rv3458c
- Product
-
30S ribosomal protein S4 RpsD
- Functional Category
-
Information pathways
- Location
- 3878659..3879264 (- strand)
- Gene Length
- 605 bp
- Nucleotides
-
ATGGCTCGTTACACCGGACCCGTCACCCGCAAATCACGGCGGTTGCGCACCGACCTCGTCGGTGGCGACCAGGCCTTCGAGAAGCGTCCCTACCCGCCCGGCCAACACGGTCGCGCGCGGATCAAGGAAAGCGAATATCTGCTTCAGCTGCAGGAGAAGCAGAAGGCCCGTTTCACATACGGCGTAATGGAAAAGCAGTTCCGCCGCTACTACGAAGAGGCCGTGCGGCAGCCCGGCAAGACGGGTGAAGAACTGCTGAAGATCCTCGAAAGCCGGCTGGACAACGTCATCTACCGTGCCGGGCTGGCGCGCACCCGGCGGATGGCTCGCCAGCTGGTCAGCCACGGGCATTTCAACGTCAACGGCGTGCACGTCAACGTCCCCAGTTACCGGGTGTCGCAGTACGACATCGTCGACGTGCGGGACAAGTCCCTGAACACGGTGCCGTTCCAGATTGCCCGGGAGACGGCGGGCGAGCGTCCGATCCCGAGCTGGCTGCAAGTGGTGGGGGAGCGGCAACGCGTCCTGATCCACCAGCTACCCGAGCGCGCGCAGATCGACGTCCCACTCACCGAGCAGCTGATCGTCGAGTACTACTCAAAGTA
- Drug Resistance
- Mutations
- Function
- One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. {ECO:0000255|HAMAP-Rule:MF_01306}.; FUNCTION: With S5 and S12 plays an important role in translational accuracy. {ECO:0000255|HAMAP-Rule:MF_01306}.
- Family
-
Universal ribosomal protein uS4 family
- GO
-
- structural constituent of ribosome GO:0003735 molecular_function
- small ribosomal subunit GO:0015935 cellular_component
- rRNA binding GO:0019843 molecular_function
- cell wall GO:0005618 cellular_component
- cytosol GO:0005829 cellular_component
- positive regulation of translational fidelity GO:0045903 biological_process
- plasma membrane GO:0005886 cellular_component
- translation GO:0006412 biological_process
- InterPro
Summary
- Name
- 30S ribosomal protein S4
- Family
- Universal ribosomal protein uS4 family
- Protein Sequence
-
MARYTGPVTRKSRRLRTDLVGGDQAFEKRPYPPGQHGRARIKESEYLLQLQEKQKARFTYGVMEKQFRRYYEEAVRQPGKTGEELLKILESRLDNVIYRAGLARTRRMARQLVSHGHFNVNGVHVNVPSYRVSQYDIVDVRDKSLNTVPFQIARETAGERPIPSWLQVVGERQRVLIHQLPERAQIDVPLTEQLIVEYYSK
- Mass
- 23,476 Da
- Length
- 201 Aa
Rv3458c doesn't seem to be a targeted by any drug.
-
-
Ribosome mtu03010
mtu03010PATHWAY_MAP mtu03010 Ribosome
-
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis.
- BMC Syst Biol. 2008 Dec 19;2:109. doi: 10.1186/1752-0509-2-109.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.