rpsM



Type
protein_coding
Name
rpsM
Locus Name

Rv3460c

Product

30S ribosomal protein S13 RpsM

Functional Category

Information pathways

Location
3879696..3880070 (- strand)
Gene Length
374 bp
Nucleotides
ATGGCTCGACTCGTCGGCGTCGACCTGCCGCGCGATAAGCGGATGGAGGTCGCCCTGACCTACATCTTTGGCATCGGCCGTACCCGCTCGAACGAAATCCTGGCGGCCACCGGCATTGACCGGGATCTGCGCACCAGAGATCTCACCGAAGAACAGCTGATCCACCTGCGCGACTACATCGAAGCGAACCTGAAGGTGGAGGGTGACCTGCGCCGCGAGGTACAGGCCGACATCCGTCGCAAGATCGAGATTGGCTGCTATCAGGGGTTGCGGCACCGCCGCGGTATGCCGGTACGCGGCCAGCGGACAAAAACCAACGCGCGGACCCGCAAAGGCCCCAAGCGCACCATCGCAGGCAAGAAGAAGGCTAGGTA
Drug Resistance

Check for drug resistance association at TBDREAMDB

Mutations

Check for mutants available at TARGET


Function
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. {ECO:0000255|HAMAP-Rule:MF_01315}.
Family

Universal ribosomal protein uS13 family

GO
InterPro

UniProt
P9WH61
GenBank
Rv3460c
EnsemblBacteria
Rv3460c
Mycobrowser
Rv3460c


Summary
Name
30S ribosomal protein S13
Family
Universal ribosomal protein uS13 family
Protein Sequence
MARLVGVDLPRDKRMEVALTYIFGIGRTRSNEILAATGIDRDLRTRDLTEEQLIHLRDYIEANLKVEGDLRREVQADIRRKIEIGCYQGLRHRRGMPVRGQRTKTNARTRKGPKRTIAGKKKAR
Mass
14,351 Da
Length
124 Aa

Rv3460c doesn't seem to be a targeted by any drug.


  • Ribosome

    Ribosome mtu03010

    mtu03010

    PATHWAY_MAP mtu03010 Ribosome


Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.