Gene - combatTB X

mce4F

Type: protein_coding
Name: mce4F
Locus Name: Rv3494c
Product: Mce-family protein Mce4F
Functional Category: Virulence, detoxification, adaptation
Location: 3911675..3913369 (- strand)
Gene Length: 1694 bp
Nucleotides: ATGATCGACCGACTCGCCAAGATCCAGTTGTCCATTTTTGCGGTGATCACCGTCATCACCCTGAGCGTGATGGCGATCTTTTATCTGCGTCTGCCCGCCACGTTCGGCATCGGAACCTACGGCGTGAGTGCCGACTTCGTCGCGGGCGGTGGCCTGTACAAGAACGCCAACGTCACCTACCGCGGTGTCGCGGTCGGGCGGGTGGAGTCGGTGGGGCTAAATCCCAATGGCGTTACCGCGCACATGCGACTGAACAGTGGCACCGCCATTCCGTCGAACGTCACCGCCACCGTACGCAGCGTTTCGGCCATCGGTGAGCAGTACATCGACCTAGTGCCGCCGGAGAACCCGTCGTCGACCAAGTTGCGCAACGGCTTCCGGATCCAGCGGCAGAACACCCGAATCGGGCAAGACGTCGCCGACCTGTTGCGTCAGGCCGAGACGCTGCTCGGCAGCCTTGGCGACACCCGGCTGCGGGAGCTGCTGCACGAGGCGTTCATCGCGACCAATGGCGCCGGTCCGGAACTGGCCCGGCTGATCGAGTCGGCCCGGTTGCTGGTGGATGAGGCCAACGCCAACTATCCACAGGTTTCGCAGTTGATCGATCAGGCCGGCCCGTTCCTGCAAGCCCAGATCCGCGCCGGCGGGGACATCAAGTCACTCGCCGATGGGCTGGCGCGGTTCACCTGGCAGCTCCGTGCGGCAGACCCGCGGCTGCGCGACACGTTGGCCGACGCCCCGGATGCGATCGACGAGGCCAACACCGCGTTCTCCGGGATTCGTCCTTCGTTTCCCGCGCTGGCGGCCAGTCTGGCCAACCTGGGCCGGGTGGGCGTGATCTATCACAAGTCGATCGAACAGCTCCTGGTGGTTTTCCCGGCGCTGTTCGCCGCGATCATCACCTCGGCGGGCGGCGTACCCCAGGACGAGGGCGCCAAGCTGGACTTCAAGATCGACCTGCACGACCCGCCGCCCTGCATGACCGGGTTCTTGCCCCCGCCGCTGGTCCGGTCGCCGGCCGACGAGTCGGTACGCGAGATTCCCCGGGACATGTACTGCAAGACCGCGCAGAACGACCCGAGCACGGTGCGCGGCGCTCGCAACTACCCGTGCCAGGAATTCCCCGGTAAGCGGGCACCGACGGTGCAGTTATGTCGGGATCCGCGTGGCTATGTGCCAGTTGGAACCAACCCGTGGCGCGGTCCGCCGATCCCGTACGGCACCGAGGTGACGGATGGGCGAAACATTCTGCCGCCCAACAAGTTCCCTTACATCCCGCCGGGCGCGGATCCCGACCCGGGCGTGCCCATCGTCGGACCGCCGCCACCCGGCCAGGTGGCCGGCCCCGGGCCGGCGCCGCACCAGCCGGCGCAGCCTGCGCCGCCGCCCAACGACAACGGTCCGCCTCCACCGTTCACGTCATGGATGCCGCCCGGGTACCCGCCGGAGCCACCCCAGGTGCCATACCCGGCGACCATTCCGCCGCCGCCACCACCGGAAGGCACCGGGCCTCCGCCCGGGCCGGCGCCTGGCCCCCAACCGCAGGCCAGCGGTCCGGCCTACACCATCTATGACCAACTCAGCGGAGCCTTCGCGGACCCGGCCGGCGGCACTGGTATCTTCGCGCCCGGGATGACGGGCGCATCCAGCGCCGAGAATTGGGTGGATCTCATGCGCGATCCGAGGCAGCTGTA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Unknown

GO

growth of symbiont in host organelle GO:0044121 biological_process
growth of symbiont in host GO:0044117 biological_process

InterPro

UniProt: I6YC95
GenBank: Rv3494c
EnsemblBacteria: Rv3494c
Mycobrowser: Rv3494c

Summary

Name: Mce-family protein Mce4F
Family: Unknown
Protein Sequence: MIDRLAKIQLSIFAVITVITLSVMAIFYLRLPATFGIGTYGVSADFVAGGGLYKNANVTYRGVAVGRVESVGLNPNGVTAHMRLNSGTAIPSNVTATVRSVSAIGEQYIDLVPPENPSSTKLRNGFRIQRQNTRIGQDVADLLRQAETLLGSLGDTRLRELLHEAFIATNGAGPELARLIESARLLVDEANANYPQVSQLIDQAGPFLQAQIRAGGDIKSLADGLARFTWQLRAADPRLRDTLADAPDAIDEANTAFSGIRPSFPALAASLANLGRVGVIYHKSIEQLLVVFPALFAAIITSAGGVPQDEGAKLDFKIDLHDPPPCMTGFLPPPLVRSPADESVREIPRDMYCKTAQNDPSTVRGARNYPCQEFPGKRAPTVQLCRDPRGYVPVGTNPWRGPPIPYGTEVTDGRNILPPNKFPYIPPGADPDPGVPIVGPPPPGQVAGPGPAPHQPAQPAPPPNDNGPPPPFTSWMPPGYPPEPPQVPYPATIPPPPPPEGTGPPPGPAPGPQPQASGPAYTIYDQLSGAFADPAGGTGIFAPGMTGASSAENWVDLMRDPRQL
Mass: 59,637 Da
Length: 564 Aa

Rv3494c doesn't seem to be a targeted by any drug.

ABC transporters mtu02010
mtu02010
Environmental Information Processing; Membrane transport

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.