Gene - combatTB X

Type: protein_coding
Name: Rv3502c
Locus Name: Rv3502c
Product: Probable short-chain type dehydrogenase/reductase. Possible 17-beta-hydroxysteroid dehydrogenase.
Functional Category: Intermediary metabolism and respiration
Location: 3921087..3922040 (- strand)
Gene Length: 953 bp
Nucleotides: TTGAAATTGACTGAGTCCAATCGCTCGCCGCGTACCACGAACACGACCGATCTGTCCGGAAAGGTGGCGGTGGTCACCGGCGCGGCCGCGGGTTTGGGTCGGGCCGAAGCGCTCGGCCTGGCCCGGTTGGGCGCCACCGTCGTCGTCAACGATGTTGCTTCCGCCCTGGATGCTTCCGACGTCGTCGACGAGATCGGCGCCGCCGCTGCCGATGCTGGTGCTAAGGCCGTCGCGGTAGCCGGTGATATCAGCCAGCGCGCGACGGCCGACGAACTGCTCGCCAGCGCCGTCGGGCTGGGCGGACTGGACATCGTGGTGAACAATGCCGGCATCACCCGCGACCGGATGCTGTTCAACATGTCCGACGAGGAGTGGGACGCCGTGATCGCGGTGCACCTGCGCGGCCATTTTCTGCTCACCCGCAACGCCGCTGCCTACTGGCGGGACAAAGCCAAGGATGCCGAAGGGGGATCGGTCTTCGGCCGGCTCGTCAACACCTCGTCGGAGGCGGGTCTGGTGGGCCCGGTGGGGCAGGCGAATTACGCCGCCGCCAAGGCTGGCATCACCGCGCTAACCCTGTCGGCGGCGCGGGCGCTCGGGCGCTACGGCGTTTGCGCCAATGTGATTTGTCCGCGGGCGCGCACCGCGATGACGGCCGATGTCTTCGGCGCCGCACCCGATGTCGAAGCGGGCCAGATCGACCCGCTGTCGCCGCAGCATGTGGTAAGCCTGGTCCAGTTTCTGGCGTCCCCGGCTGCCGCGGAAGTCAACGGTCAGGTGTTCATCGTCTACGGTCCGCAGGTGACGCTGGTGTCACCGCCGCACATGGAGCGCCGGTTCAGCGCGGACGGCACGTCCTGGGATCCCACCGAGCTCACCGCGACGCTGCGGGACTACTTTGCTGGTCGGGATCCGGAACAGAGCTTTTCGGCGACCGATCTGATGCGTCAGTG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Short-chain dehydrogenases/reductases (SDR) family

GO

InterPro

Summary

Name: Probable short-chain type dehydrogenase/reductase. Possible 17-beta-hydroxysteroid dehydrogenase
Family: Short-chain dehydrogenases/reductases (SDR) family
Protein Sequence: MKLTESNRSPRTTNTTDLSGKVAVVTGAAAGLGRAEALGLARLGATVVVNDVASALDASDVVDEIGAAAADAGAKAVAVAGDISQRATADELLASAVGLGGLDIVVNNAGITRDRMLFNMSDEEWDAVIAVHLRGHFLLTRNAAAYWRDKAKDAEGGSVFGRLVNTSSEAGLVGPVGQANYAAAKAGITALTLSAARALGRYGVCANVICPRARTAMTADVFGAAPDVEAGQIDPLSPQHVVSLVQFLASPAAAEVNGQVFIVYGPQVTLVSPPHMERRFSADGTSWDPTELTATLRDYFAGRDPEQSFSATDLMRQ
Mass: 32,753 Da
Length: 317 Aa

Rv3502c doesn't seem to be a targeted by any drug.

Biotin metabolism mtu00780
mtu00780
Metabolism; Metabolism of cofactors and vitamins

Fatty acid biosynthesis mtu00061
mtu00061
PATHWAY_MAP mtu00061 Fatty acid biosynthesis

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.