Gene - combatTB X

PPE63

Type: protein_coding
Name: PPE63
Locus Name: Rv3539
Product: PPE family protein PPE63
Functional Category: Pe/ppe
Location: 3978059..3979498 (+ strand)
Gene Length: 1439 bp
Nucleotides: TGGCGGATTTCTTGACGTTGTCACCAGAGGTGAATTCGGCCCGGATGTACGCGGGTGGGGGGCCCGGGTCGCTATCGGCGGCCGCGGCGGCCTGGGATGAGTTGGCCGCCGAACTGTGGTTGGCGGCGGCCTCGTTCGAGTCGGTGTGCTCCGGCCTGGCGGACCGTTGGTGGCAAGGGCCGTCGTCTCGGATGATGGCGGCGCAGGCCGCCCGCCATACGGGGTGGCTGGCCGCGGCGGCCACCCAGGCAGAGGGAGCAGCCAGCCAGGCTCAGACGATGGCGCTGGCCTATGAAGCGGCGTTCGCCGCAACCGTACACCCGGCGCTGGTCGCGGCGAACCGCGCCCTCGTGGCCTGGTTGGCGGGGTCGAATGTGTTCGGGCAGAACACCCCGGCGATTGCGGCCGCCGAGGCCATCTACGAGCAGATGTGGGCTCAGGATGTTGTCGCGATGTTGAACTACCATGCGGTGGCCTCGGCGGTCGGGGCGCGGTTGCGGCCGTGGCAGCAGTTGCTGCATGAGCTGCCCAGGCGGTTGGGCGGCGAACACTCCGACAGCACAAACACGGAACTCGCTAACCCGAGTTCAACGACGACACGCATTACCGTCCCCGGCGCATCTCCGGTGCATGCAGCGACGTTACTGCCGTTCATCGGAAGGCTACTGGCGGCGCGTTATGCCGAGCTGAACACCGCGATCGGCACGAACTGGTTTCCGGGCACCACGCCAGAAGTGGTGAGCTATCCGGCCACCATCGGGGTCCTTAGCGGCTCTCTTGGCGCCGTCGATGCCAACCAGTCCATCGCTATCGGTCAGCAGATGTTGCACAACGAGATCCTGGCCGCCACGGCCTCCGGTCAGCCGGTGACGGTGGCCGGACTGTCGATGGGCAGCATGGTCATCGACCGCGAACTTGCCTATCTGGCCATCGACCCCAACGCGCCACCCTCGAGCGCGCTCACATTCGTCGAGCTCGCCGGCCCGGAACGCGGTCTTGCCCAGACCTACCTGCCCGTTGGCACCACCATTCCAATCGCGGGGTACACCGTGGGGAATGCGCCCGAGAGCCAGTACAACACCAGCGTGGTTTATAGCCAGTACGATATCTGGGCCGATCCGCCCGACCGTCCGTGGAACCTGTTGGCCGGCGCCAACGCACTGATGGGCGCGGCTTACTTTCACGATCTGACCGCCTACGCCGCACCACAACAGGGGATAGAGATCGCCGCTGTCACGAGTTCACTGGGCGGAACCACGACAACGTACATGATTCCGTCGCCCACGCTGCCGTTGCTGTTGCCACTGAAGCAGATCGGTGTCCCAGACTGGATCGTCGGCGGGCTGAACAACGTGCTGAAGCCGCTCGTCGACGCGGGCTACTCACAGTACGCCCCCACCGCCGGCCCTTATTTCAGCCACGGCAACCTGGTGTGGTAG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Mycobacterial PPE family

GO

plasma membrane GO:0005886 cellular_component

InterPro

UniProt: P9WHX5
GenBank: Rv3539
EnsemblBacteria: Rv3539
Mycobrowser: Rv3539

Summary

Name: Uncharacterized PPE family protein PPE63
Family: Mycobacterial PPE family
Protein Sequence: MADFLTLSPEVNSARMYAGGGPGSLSAAAAAWDELAAELWLAAASFESVCSGLADRWWQGPSSRMMAAQAARHTGWLAAAATQAEGAASQAQTMALAYEAAFAATVHPALVAANRALVAWLAGSNVFGQNTPAIAAAEAIYEQMWAQDVVAMLNYHAVASAVGARLRPWQQLLHELPRRLGGEHSDSTNTELANPSSTTTRITVPGASPVHAATLLPFIGRLLAARYAELNTAIGTNWFPGTTPEVVSYPATIGVLSGSLGAVDANQSIAIGQQMLHNEILAATASGQPVTVAGLSMGSMVIDRELAYLAIDPNAPPSSALTFVELAGPERGLAQTYLPVGTTIPIAGYTVGNAPESQYNTSVVYSQYDIWADPPDRPWNLLAGANALMGAAYFHDLTAYAAPQQGIEIAAVTSSLGGTTTTYMIPSPTLPLLLPLKQIGVPDWIVGGLNNVLKPLVDAGYSQYAPTAGPYFSHGNLVW
Mass: 49,970 Da
Length: 479 Aa

Rv3539 doesn't seem to be a targeted by any drug.

Rv3539 doesn't seem to be involved in any pathway.

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.