Gene - combatTB X

fdxB

Type: protein_coding
Name: fdxB
Locus Name: Rv3554
Product: Possible electron transfer protein FdxB
Functional Category: Intermediary metabolism and respiration
Location: 3992685..3994742 (+ strand)
Gene Length: 2057 bp
Nucleotides: TGACTGACGCGTGTCAAGCAGAGTACGCTATCGCAGCTATGTCGACCGTCGAGATGGACCAGGCGGCTCCAGAGTCCGCCGCGCACCACCCTCTGCCGGACCCCGGTGAGTCGGTCCCCAGACTCGCGCTGCCCACGATCGGGATCTTCCTGGCCACGCTCACCGCGTTCGTCGGTTCTACGACCGCTTACATCAGCGGATGGATCCCGTTCTGGGTGACGATCCCCGTCAACGCCGCGGTCACGTTCGTGATGTTCACCGTCGTGCATGACGCATCGCATTACGCGATCAGCTCCATCCGGTGGGTGAACGGGCTGTTCGGGCGGCTGGCGTGGCTTTTCGTCGGGCCGGTGGTCGCGTTCCCGGCCTTCGGGTACATCCACATCCAGCACCACCGCCATTCCAACGACGACGAGCAAGACCCGGACACCTTCGCCTCACACGGCTCGCTGTGGGTGCTGCCGTTGCGCTGGTCGATGGTCGAGTACTTCTACATCAAGTACTACCTGCCTCGCGGCCGCAGCCGGCCGGTCATCGAGGTCGCCGAGACGCTGGTGATGATGACCCTGTTCCTGACCGGCCTGATCGTCGCCATCGTCACCGGCAACTTCTGGACGCTGGCGATCGTCTTCCTGATCCCGCAACGTATCGGCCTTACCGTGCTGGCCTGGTGGTTCGACTGGCTGCCCCACCACGGTCTGGAGGACACCCAGCGCAGCAACCGCTACCGCGCGACCCGCAACCGGGTTGGCGCCGAGTGGCTGTTCACCCCGGTGCTGCTGTCGCAGAACTACCACTTGGTGCACCACCTGCACCCGTCGGTGCCGTTCTACCGGTACCTGCGCACCTGGCGGCGCAACGAGGAGGCGTATCTGGAACGCAACGCCGCGATCTCCACGGTCTTTGGCCAGCAACTGAATCCGGACGAGTACCGGCAGTGGAAGGAGCTCAACGGCCGGCTCGCGCGACTGCTGCCGGTGCGGATGCCGGCCCGCTCCAGCTCGCCGCACGCGGTGCTGCACCGCATCCCGGTCGCGTCGGTGGATCCCATCACCGCCGATGCCACCCTGGTGACTTTCGCGGTGCCGGAAGCATTGCGGGACGCGTTCCGATTCGAGCCGGGCCAGCACGTGACGGTGCGCACCGACCTGGGCGGCCAAGGCATCCGGCGCAACTACTCGATCTGCGCCCCGGCCACCCGCGCCCAGCTGCGCATCGCCGTCAAACACATTCCCGGCGGGGCGTTTTCGACGTTCGTGGCCAACGAACTGAAGGCCGGCGACGTGCTCGAGCTGATGACACCGACCGGCCGGTTCGGCACCCCGCTGGATCCGTTGCACCGCAAGCACTATGTGGGCCTGGTGGCCGGCAGCGGGATCACCCCGGTGCTGTCCATCCTGGCGACCACGCTGGAGATCGAGACCGAAAGCCGATTCACGCTGATCTACGGCAACCGCACCAAGGAATCGACGATGTTTCGGGCCGAGCTGGATCGTCTGGAGTCGCGCTATGCCGACCGGCTGGAAATCCTGCACGTGCTCTCCAGCGAGCCGCTGCACACCCCGGAGCTGCGCGGGCGCATCGACCGAGACAAACTCACCAGGTGGCTGACGAGTACCCTGCGGCCGGCCGGTGTGGACGAATGGTTCATCTGCGGCCCGCTCGCCATGGCCACCGCGGTGCGCGAGACCCTGATCGAGCACGGCGTGGACTCCGAGCGCATTCACCTGGAGTTGTTCTACGGGTTCGACACGCCCCCGGCGACCCGTCCCTCCTATGCGGGAGCCACCGTCACCTTCACGCTGTCCGGGCAGCGGGCGATATTCGATCTGGTGCCCGGCGACTCGATTCTGGAAGGGGCGCTGGGGCTGCGCAGCGATGCGCCGTATGCGTGCATGGGCGGCGCATGCGGCACCTGCCGAGCCAAACTGATCGAGGGCAACGTCGAGATGGACCACAACTTCGCCCTCCGGAAGGCGGAGCTGGATGCCGGCTACATCCTGACCTGCCAGTCACACCCGACGACACCATTCGTCGCCGTCGACTACGACGCCTAG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Unknown

GO

metal ion binding GO:0046872 molecular_function
electron transfer activity GO:0009055 molecular_function
cytosol GO:0005829 cellular_component
2 iron, 2 sulfur cluster binding GO:0051537 molecular_function
integral component of membrane GO:0016021 cellular_component
lipid metabolic process GO:0006629 biological_process

InterPro

UniProt: P71846
GenBank: Rv3554
EnsemblBacteria: Rv3554
Mycobrowser: Rv3554

Summary

Name: Possible electron transfer protein FdxB
Family: Unknown
Protein Sequence: MTDACQAEYAIAAMSTVEMDQAAPESAAHHPLPDPGESVPRLALPTIGIFLATLTAFVGSTTAYISGWIPFWVTIPVNAAVTFVMFTVVHDASHYAISSIRWVNGLFGRLAWLFVGPVVAFPAFGYIHIQHHRHSNDDEQDPDTFASHGSLWVLPLRWSMVEYFYIKYYLPRGRSRPVIEVAETLVMMTLFLTGLIVAIVTGNFWTLAIVFLIPQRIGLTVLAWWFDWLPHHGLEDTQRSNRYRATRNRVGAEWLFTPVLLSQNYHLVHHLHPSVPFYRYLRTWRRNEEAYLERNAAISTVFGQQLNPDEYRQWKELNGRLARLLPVRMPARSSSPHAVLHRIPVASVDPITADATLVTFAVPEALRDAFRFEPGQHVTVRTDLGGQGIRRNYSICAPATRAQLRIAVKHIPGGAFSTFVANELKAGDVLELMTPTGRFGTPLDPLHRKHYVGLVAGSGITPVLSILATTLEIETESRFTLIYGNRTKESTMFRAELDRLESRYADRLEILHVLSSEPLHTPELRGRIDRDKLTRWLTSTLRPAGVDEWFICGPLAMATAVRETLIEHGVDSERIHLELFYGFDTPPATRPSYAGATVTFTLSGQRAIFDLVPGDSILEGALGLRSDAPYACMGGACGTCRAKLIEGNVEMDHNFALRKAELDAGYILTCQSHPTTPFVAVDYDA
Mass: 76,566 Da
Length: 685 Aa

Rv3554 doesn't seem to be a targeted by any drug.

Rv3554 doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.