kstR
- Type
- protein_coding
- Name
- kstR
- Locus Name
-
Rv3574
- Product
-
Transcriptional regulatory protein KstR (probably TetR-family)
- Functional Category
-
Regulatory proteins
- Location
- 4016484..4017083 (+ strand)
- Gene Length
- 599 bp
- Nucleotides
-
TGGCGGTACTTGCCGAGTCCGAGCTCGGATCGGAGGCACAGCGGGAGCGCCGCAAGCGCATCTTGGACGCCACCATGGCTATCGCGTCCAAAGGCGGCTATGAGGCGGTGCAGATGCGCGCCGTCGCCGACCGCGCCGACGTCGCGGTTGGCACGCTGTACCGGTACTTCCCGTCGAAGGTGCATCTGCTGGTGTCGGCGCTGGGTCGGGAATTCAGCCGCATCGACGCGAAAACCGACCGCTCCGCGGTCGCCGGGGCCACCCCCTTCCAGCGGCTGAACTTTATGGTCGGCAAGCTCAACCGCGCGATGCAACGCAATCCGCTACTCACCGAGGCCATGACACGTGCCTACGTGTTCGCCGACGCCTCGGCGGCCAGCGAGGTCGACCAGGTCGAAAAGCTCATCGACAGTATGTTCGCGCGTGCAATGGCCAACGGCGAACCAACCGAGGACCAGTACCACATAGCGCGGGTGATCTCGGACGTGTGGTTGTCGAACCTGCTCGCGTGGCTTACCCGACGAGCCTCGGCTACCGACGTCAGCAAGCGGCTGGACCTGGCCGTGCGGCTGCTGATCGGCGATCAAGACAGCGCCTAG
- Drug Resistance
- Mutations
- Function
- Controls the expression of genes used for utilizing diverse lipids as energy sources. {ECO:0000269|PubMed:17635188}.
- Family
-
Unknown
- GO
-
- protein homodimerization activity GO:0042803 molecular_function
- DNA binding GO:0003677 molecular_function
- regulation of transcription, DNA-templated GO:0006355 biological_process
- InterPro
3MNL
- Name
- HTH-type transcriptional repressor KstR
- Family
- Unknown
- Protein Sequence
-
MSSANTNTSSAPDAPPRAVMKVAVLAESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKTDRSAVAGATPFQRLNFMVGKLNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMANGEPTEDQYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAVRLLIGDQDSA
- Mass
- 24,050 Da
- Length
- 220 Aa
Summary
Rv3574 doesn't seem to be a targeted by any drug.
Rv3574 doesn't seem to be involved in any pathway.
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis.
- Mol Microbiol. 2007 Aug;65(3):684-99. doi: 10.1111/j.1365-2958.2007.05827.x.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.