folE
- Type
- protein_coding
- Name
- folE
- Locus Name
-
Rv3609c
- Product
-
GTP cyclohydrolase I FolE (GTP-ch-I)
- Functional Category
-
Intermediary metabolism and respiration
- Location
- 4049977..4050585 (- strand)
- Gene Length
- 608 bp
- Nucleotides
-
ATGTCGCAGCTGGATTCGCGCAGCGCATCTGCTCGTATCCGTGTGTTCGACCAGCAACGTGCCGAGGCCGCGGTGCGCGAATTGCTGTACGCGATCGGCGAGGATCCGGATAGGGACGGCTTGGTAGCCACCCCGTCCCGGGTTGCCCGGTCATACCGCGAAATGTTCGCCGGGCTCTACACCGACCCCGACTCGGTGTTGAACACCATGTTCGACGAAGACCACGACGAGCTGGTGTTGGTCAAGGAAATCCCTATGTACTCCACCTGCGAACACCACCTGGTGGCGTTCCACGGTGTGGCCCACGTCGGCTACATCCCGGGCGACGACGGCAGGGTGACCGGCTTGTCAAAGATCGCGCGACTGGTCGATCTGTACGCCAAGCGACCTCAGGTCCAGGAGCGGCTCACCAGTCAGATCGCCGATGCCCTGATGAAAAAACTCGATCCACGCGGGGTAATCGTGGTGATCGAGGCTGAGCATCTGTGCATGGCGATGCGCGGGGTTCGCAAGCCCGGCTCGGTCACCACTACGTCGGCGGTGCGCGGACTGTTCAAAACCAATGCCGCTTCTCGAGCCGAAGCGCTCGACCTCATTTTGCGGAAGTG
- Drug Resistance
- Mutations
- Function
- Unknown
- Family
-
GTP cyclohydrolase I family
- GO
-
- tetrahydrofolate biosynthetic process GO:0046654 biological_process
- one-carbon metabolic process GO:0006730 biological_process
- tetrahydrobiopterin biosynthetic process GO:0006729 biological_process
- zinc ion binding GO:0008270 molecular_function
- cytoplasm GO:0005737 cellular_component
- 7,8-dihydroneopterin 3'-triphosphate biosynthetic process GO:0035998 biological_process
- GTP binding GO:0005525 molecular_function
- GTP cyclohydrolase I activity GO:0003934 molecular_function
- InterPro
Summary
- Name
- GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I)
- Family
- GTP cyclohydrolase I family
- Protein Sequence
-
MSQLDSRSASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRAEALDLILRK
- Mass
- 22,395 Da
- Length
- 202 Aa
Rv3609c doesn't seem to be a targeted by any drug.
-
-
Folate biosynthesis mtu00790
mtu00790PATHWAY_MAP mtu00790 Folate biosynthesis
-
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.