Gene - combatTB X

recR

Type: protein_coding
Name: recR
Locus Name: Rv3715c
Product: Probable recombination protein RecR
Functional Category: Information pathways
Location: 4159889..4160500 (- strand)
Gene Length: 611 bp
Nucleotides: ATGTTTGAGGGACCCGTCCAGGACCTGATTGACGAACTCGGCAAGTTGCCGGGGATCGGACCCAAGAGTGCGCAGCGAATCGCCTTCCACCTGTTGTCGGTAGAACCGTCGGACATCGACCGGCTGACCGGTGTGCTGGCGAAGGTTCGGGACGGCGTGCGATTCTGCGCGGTGTGTGGGAATGTCTCTGACAACGAGCGTTGCAGAATCTGCTCTGATATCCGTCGCGATGCGTCCGTGGTGTGCATTGTCGAGGAACCCAAAGACATCCAGGCCGTCGAGCGCACCCGCGAGTTCCGGGGTCGCTATCACGTCCTGGGCGGGGCGCTTGACCCGCTGTCCGGAATTGGGCCGGATCAGCTGCGGATCCGCGAACTGCTGAGCCGCATCGGGGAACGGGTCGACGACGTCGACGTCACCGAGGTCATCATCGCCACCGACCCCAACACCGAGGGCGAGGCGACGGCCACCTACCTGGTGCGAATGCTGCGCGACATCCCCGGCCTGACCGTCACACGGATCGCGTCCGGGCTGCCGATGGGCGGTGACCTGGAATTCGCCGACGAGCTCACCCTGGGCCGAGCGCTCGCCGGCCGCCGCGTGCTCGCCTG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. {ECO:0000255|HAMAP-Rule:MF_00017}.

Family

RecR family

GO

metal ion binding GO:0046872 molecular_function
DNA binding GO:0003677 molecular_function
DNA repair GO:0006281 biological_process
DNA recombination GO:0006310 biological_process

InterPro

UniProt: P9WHI3
GenBank: Rv3715c
EnsemblBacteria: Rv3715c
Mycobrowser: Rv3715c

Summary

Name: Recombination protein RecR
Family: RecR family
Protein Sequence: MFEGPVQDLIDELGKLPGIGPKSAQRIAFHLLSVEPSDIDRLTGVLAKVRDGVRFCAVCGNVSDNERCRICSDIRRDASVVCIVEEPKDIQAVERTREFRGRYHVLGGALDPLSGIGPDQLRIRELLSRIGERVDDVDVTEVIIATDPNTEGEATATYLVRMLRDIPGLTVTRIASGLPMGGDLEFADELTLGRALAGRRVLA
Mass: 22,119 Da
Length: 203 Aa

Rv3715c doesn't seem to be a targeted by any drug.

Homologous recombination mtu03440
mtu03440
Genetic Information Processing; Replication and repair

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.