Gene - combatTB X

Rv3779

Type: protein_coding
Name: Rv3779
Locus Name: Rv3779
Product: Probable conserved transmembrane protein alanine and leucine rich
Functional Category: None
Location: 4224985..4226985 (+ strand)
Gene Length: 2000 bp
Nucleotides: TGGGCCTGTGGTTCGGTACGCTAATCGCTTTGATTTTGCTGATAGCGCCGGGGGCAATGGTTGCTCGCATCGCCCAGCTGAGGTGGCCGGTCGCCATCGCGGTTGGCCCGGCGCTGACATACGGCGTGGTGGCACTCGCGATCATCCCCTATGGCGCGCTCGGAATTCCCTGGAACGGTTGGACCGCGCTGGCCGCCTTGGCGGTGACGTGCGCTGTAGCGACCGGTTTGCAGCTACTGCTTGCCCGTTTTCGGGACCTCGACGCCGAGGCACTTGCGGTTAGCCGCTGGCCCGCGGTTACGGTCGCCGCCGGGGTGCTGCTGGGCGCCCTGTTGATCGGATGGGCCGCATATCGCGGCATACCGCACTGGCAGTCCATCCCCAGCACCTGGGACGCGGTCTGGCACGCCAACACCGTACGTTTCATCCTGGACACCGGCCAGGCGTCCTCGACTCACATGGGGGAGCTTCGCAACGTCGAGACCCATGCCCCGTTGTACTACCCGTCGGTGTTCCACGGGCTGGTCGCGGTGTTCTGCCAGTTAACCGGCGCGGCACCCACCACCGGCTACACACTGAGTTCGCTGGCCGCCTCGGTCTGGCTGTTTCCGGTCAGTGCAGCCGTTCTCACCTGGCGCGCGGTGCGCTCACACCCGGGCGCGCTGTGGTCGGCCTCCTGCGCCTCGGCAGAGTGGCGCGCCGCCGGAGCGGCGGGCACCGCCGCGGCACTCTCGGCGTCGTTCACCGCGGTGCCCTACGTCGAGTTCGATACCGCCGCTATGCCCAACCTGGCGGCCTACGGCATCGCGGTGCCGACGATGGTGCTGATCACCTCGACATTGCGGCACCGCGACCGCATCCCGGTGGCCGTGCTAGCGCTGGTCGGCGTCTTCTCACTGCACATTACCGGCGGTATCGTCGTAGCGCTGTTGGTGTCGGCCTGGTGGCTTTTCGAGGCACTGCGGCATCCTGTGCGATCAAGGCTGGCCGACCTGTTGACGCTGGCCGGCGTGGCAGCGATGGCCGGGTTGGTCATGTTGCCGCAGTTCTTGAGCGTCAGGCAGCAGGAAGACATCATCGCCGGACACGCTTTTCCCACCTATCTCAGCAAGAAGCGTGGGCTGTTCGACGCTGTTTTCCAGCACTCCCGCCATCTCAACGACTTCCCGGTCCAGTACGCGCTCATTGTGTTGGCCGCCATCGGCGGGCTCATTCTGCTGGTCAAGAAGATCTGGTGGCCGCTGGCGGTTTGGCTGCTGTTGATTGTGATGAACGTCGACGCGGGAACACCGTTGGGCGGACCTATCGGAGGGGTGGCCGGCGCACTCGGCGAGTTCTTCTATCACGATCCGCGCCGCATCGCGGCGGCCACAACCCTGCTGTTGATGCTGATGGCAGGTGTGGCGCTGTTCGCGACAGTCATGTTGCTAGTGGCCGCGGCGAAACGACTGACCGACCGTTTCAGACCCCAGCCGGTGTCTGTCTGGGCATCGGCGACCGCGACACTACTGATCGGAGCCACTCTGGTCAGTGCGTGGCATTACTTTCCCCGGCACCGATTTCTGTTCGGCGACAAGTACGACTCGGTGATGATCGACCAGAAAGATCTCGACGCCATGGCATACCTGGCGAGTTTGCCCGGCGCACGCGACACGTTGATTGGCAACGCCAACACGGACGGCACCGCGTGGATGTATGCCGTGGCCGGCCTACACCCGCTGTGGACCCACTACGACTACCCGCTGCAACAGGGCCCGGGCTATCACCGGTTCATCTTCTGGGCCTATGGCCGCAACGGGGAGAGCGATCCTCGGGTACTCGAGGCCATCCAAGTCCTCCGTATCCGCTATATCCTGACCAGCACTCCGACGGTGCGGGGGTTTGCCGTGCCGGACGGACTAGTGTCGTTAGAGACATCGAGGTCGTGGGCGAAGATCTACGACAACGGCGAGGCCCGAATCTACGAATGGCGCGGCACTGCCGCAGCAACACACTCCTAG
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Unknown

GO

glycolipid biosynthetic process GO:0009247 biological_process
positive regulation of growth rate GO:0040010 biological_process
extracellular region GO:0005576 cellular_component
transferase activity, transferring hexosyl groups GO:0016758 molecular_function
integral component of membrane GO:0016021 cellular_component

InterPro

Unknown

UniProt: P72045
GenBank: Rv3779
EnsemblBacteria: Rv3779
Mycobrowser: Rv3779

Summary

Name: Probable conserved transmembrane protein alanine and leucine rich
Family: Unknown
Protein Sequence: MGLWFGTLIALILLIAPGAMVARIAQLRWPVAIAVGPALTYGVVALAIIPYGALGIPWNGWTALAALAVTCAVATGLQLLLARFRDLDAEALAVSRWPAVTVAAGVLLGALLIGWAAYRGIPHWQSIPSTWDAVWHANTVRFILDTGQASSTHMGELRNVETHAPLYYPSVFHGLVAVFCQLTGAAPTTGYTLSSLAASVWLFPVSAAVLTWRAVRSHPGALWSASCASAEWRAAGAAGTAAALSASFTAVPYVEFDTAAMPNLAAYGIAVPTMVLITSTLRHRDRIPVAVLALVGVFSLHITGGIVVALLVSAWWLFEALRHPVRSRLADLLTLAGVAAMAGLVMLPQFLSVRQQEDIIAGHAFPTYLSKKRGLFDAVFQHSRHLNDFPVQYALIVLAAIGGLILLVKKIWWPLAVWLLLIVMNVDAGTPLGGPIGGVAGALGEFFYHDPRRIAAATTLLLMLMAGVALFATVMLLVAAAKRLTDRFRPQPVSVWASATATLLIGATLVSAWHYFPRHRFLFGDKYDSVMIDQKDLDAMAYLASLPGARDTLIGNANTDGTAWMYAVAGLHPLWTHYDYPLQQGPGYHRFIFWAYGRNGESDPRVLEAIQVLRIRYILTSTPTVRGFAVPDGLVSLETSRSWAKIYDNGEARIYEWRGTAAATHS
Mass: 71,795 Da
Length: 666 Aa

Rv3779 doesn't seem to be a targeted by any drug.

Arabinogalactan biosynthesis - Mycobacterium mtu00572
mtu00572
Metabolism; Glycan biosynthesis and metabolism

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.