Gene - combatTB X

fadE35

Type: protein_coding
Name: fadE35
Locus Name: Rv3797
Product: Probable acyl-CoA dehydrogenase FadE35
Functional Category: None
Location: 4251085..4252866 (+ strand)
Gene Length: 1781 bp
Nucleotides: TGCCCGAGTACGACCTAGAGGCCGTGGACAAGCTGCCCTTCTCGACCCCTGAAAAGGCGCAGCGCTACCAAACGGAAAACTATCGCGGGGCCATGGGCCTCAACTGGTACCTCACGGATCCGACCCTGCAGTTCATCATGGCCTATTACCTACGACCCGATGAATTGGCGTTCGCAGAACCCCATCTGACCCGCATTGGTGAGCTGACGGGGGGGCCAGTGACGCGTTGGGCCGAGGAAACCGACCGCAACCCCCCGCGGCTCGAACGCTACGACCGGTGGGGGCATGACATCAGCCGGGTAGTGCTGCCGGAATCGTTCATCCAATCCAAGCGCGCCGTCATCGAGGCGCGACAAGCCGTGCGCGACGACGCGGCACGGGCCGGCGTCAAGCCGTCGCTGGCACTCTTCGCCGCCGACTATCTGCTCAACCAGGCCGATATCGGTATGGCTTGCGCGCTCGCCACTGGCGGCAACATGGTCCGGTCGCTGGTGACTGCCTACGCGCCACCCGATGTGCGCGAATTCGTCCTAGGCAAACTCAATTCCGGCGAGTGGGACGGCGAGGCCGCGCAGCTGCTGACGGAGCGTGCGGGCGGCTCCGATCTGGGAGCTCTGGAGACGACGGCCACCCGCAGCGGCGACGTGTGGCTGCTGAACGGCTTCAAGTGGTTTGCGTCCAACTGCGCCGGGGAGGCGTTCGTGGTGTTGGCCAAGCCCGAGGGGGCGCCTGACTCGACTCGAGGTGTGGCCACCTTCCTCGTGCTACGGACGCGCCGTGACGGTTCCCGCAACGGCGTGCGTATCCGTCGGCTGAAGGACAAGCTCGGCACCCGCTCTGTCGCCTCCGGTGAAATCGAGTTCGTCGACGCCGAAGCCTTTCTGTTGTCCGGCGAACCGAGCGCTGACGCGGGCCCGTCCGACGGCAAGGGACTCACCCGCATGATGGAGCTGACCAACAGATTGCGGTTGGGCACCGCCTCGTTCGCCCTCGGCAACGCGCGCCGCGCGCTGGTCGAATCGCTGTGCTACGCCGGGCAGCGGCGGGCATTCGGTGGGGCGCTCATCGACAAGCCGCTGATGCGCCGCAAGCTGGCCGAAATGGTCGTTGATGTGGAAGCCGCGCTGGCGATGGTGTTCGACGGCTTCGGAGCGGCGAACCACCGCCAGCCCAGATGCCTGCCGCAACGTATCGCGGTGCCGGTCACCAAGCTTAAGACTTGCCGGCTCGGGATCACCGTGGCATCGGATGCGATCGAGATCCACGGCGGCAATGGCTACATCGAGACCTGGCCGGTGGCCCGGTTGCTGCGTGACGCGCAAGTCAACACGATCTGGGAGGGCCCCGACAACATCCTGTGTCTGGATGTGCGGCGCGGGATCGAGCAGACGCGCGCTCACGAGACACTGTTGGCGCGGCTGCGCGATGCGGTGTCGGTGTCCGACGATGACGACACCACGCGGCTGGTCTCGCGCCGCATTGAGGACCTCGACGCGGCGATCACCGCTTGGACCAAACTCGACAGGCAGCTGGCCGAGGCGCGGCTGTTCCCGCTGGCCCAATTCATGGGCGACGTCTACGCCGGCGCGTTGCTCACCGAGCAGGCCGCCTGGGAACGGGCAACCCGCGGCACCGACCGCAAGGCACTCGTCGCCCGCCTGTACGCGCGCCGGTATCTCGCCGACCAAGGCCCGCTGCGCGGTATCGACGCAGATTGCGATGAGGCGCTGCAGCGTTTCGACGAACTCGTGGCGGGCGCGTTCACTGCCGAGCAGACGTAA
Drug Resistance: Check for drug resistance association at TBDREAMDB
Mutations: Check for mutants available at TARGET

Function

Unknown

Family

Acyl-CoA dehydrogenase family

GO

flavin adenine dinucleotide binding GO:0050660 molecular_function
oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 molecular_function

InterPro

UniProt: O53577
GenBank: Rv3797
EnsemblBacteria: Rv3797
Mycobrowser: Rv3797

Summary

Name: Probable acyl-CoA dehydrogenase FadE35
Family: Acyl-CoA dehydrogenase family
Protein Sequence: MPEYDLEAVDKLPFSTPEKAQRYQTENYRGAMGLNWYLTDPTLQFIMAYYLRPDELAFAEPHLTRIGELTGGPVTRWAEETDRNPPRLERYDRWGHDISRVVLPESFIQSKRAVIEARQAVRDDAARAGVKPSLALFAADYLLNQADIGMACALATGGNMVRSLVTAYAPPDVREFVLGKLNSGEWDGEAAQLLTERAGGSDLGALETTATRSGDVWLLNGFKWFASNCAGEAFVVLAKPEGAPDSTRGVATFLVLRTRRDGSRNGVRIRRLKDKLGTRSVASGEIEFVDAEAFLLSGEPSADAGPSDGKGLTRMMELTNRLRLGTASFALGNARRALVESLCYAGQRRAFGGALIDKPLMRRKLAEMVVDVEAALAMVFDGFGAANHRQPRCLPQRIAVPVTKLKTCRLGITVASDAIEIHGGNGYIETWPVARLLRDAQVNTIWEGPDNILCLDVRRGIEQTRAHETLLARLRDAVSVSDDDDTTRLVSRRIEDLDAAITAWTKLDRQLAEARLFPLAQFMGDVYAGALLTEQAAWERATRGTDRKALVARLYARRYLADQGPLRGIDADCDEALQRFDELVAGAFTAEQT
Mass: 65,322 Da
Length: 593 Aa

Rv3797 doesn't seem to be a targeted by any drug.

Rv3797 doesn't seem to be involved in any pathway.

Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.: Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.: Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.