fbpD
- Type
- protein_coding
- Name
- fbpD
- Locus Name
-
Rv3803c
- Product
-
Secreted MPT51/MPB51 antigen protein FbpD (MPT51/MPB51 antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-binding protein C) (85C)
- Functional Category
-
None
- Location
- 4264563..4265462 (- strand)
- Gene Length
- 899 bp
- Nucleotides
-
ATGAAGGGTCGGTCGGCGCTGCTGCGGGCGCTCTGGATTGCCGCACTGTCATTCGGGTTGGGCGGTGTCGCGGTAGCCGCGGAACCCACCGCCAAGGCCGCCCCATACGAGAACCTGATGGTGCCGTCGCCCTCGATGGGCCGGGACATCCCGGTGGCCTTCCTAGCCGGTGGGCCGCACGCGGTGTATCTGCTGGACGCCTTCAACGCCGGCCCGGATGTCAGTAACTGGGTCACCGCGGGTAACGCGATGAACACGTTGGCGGGCAAGGGGATTTCGGTGGTGGCACCGGCCGGTGGTGCGTACAGCATGTACACCAACTGGGAGCAGGATGGCAGCAAGCAGTGGGACACCTTCTTGTCCGCTGAGCTGCCCGACTGGCTGGCCGCTAACCGGGGCTTGGCCCCCGGTGGCCATGCGGCCGTTGGCGCCGCTCAGGGCGGTTACGGGGCGATGGCGCTGGCGGCCTTCCACCCCGACCGCTTCGGCTTCGCTGGCTCGATGTCGGGCTTTTTGTACCCGTCGAACACCACCACCAACGGTGCGATCGCGGCGGGCATGCAGCAATTCGGCGGTGTGGACACCAACGGAATGTGGGGAGCACCACAGCTGGGTCGGTGGAAGTGGCACGACCCGTGGGTGCATGCCAGCCTGCTGGCGCAAAACAACACCCGGGTGTGGGTGTGGAGCCCGACCAACCCGGGAGCCAGCGATCCCGCCGCCATGATCGGCCAAGCCGCCGAGGCGATGGGTAACAGCCGCATGTTCTACAACCAGTATCGCAGCGTCGGCGGGCACAACGGACACTTCGACTTCCCAGCCAGCGGTGACAACGGCTGGGGCTCGTGGGCGCCCCAGCTGGGCGCTATGTCGGGCGATATCGTCGGTGCGATCCGCTA
- Drug Resistance
- Mutations
- Function
- May have a role in host tissue attachment, whereby ligands may include the serum protein fibronectin and small sugars. {ECO:0000269|PubMed:14672660}.
- Family
-
Mycobacterial A85 antigen family
- GO
-
- mycolate cell wall layer assembly GO:0071769 biological_process
- extracellular region GO:0005576 cellular_component
- fibronectin binding GO:0001968 molecular_function
- zymogen binding GO:0035375 molecular_function
- transferase activity, transferring acyl groups other than amino-acyl groups GO:0016747 molecular_function
- InterPro
1R88
- Name
- MPT51/MPB51 antigen
- Family
- Mycobacterial A85 antigen family
- Protein Sequence
-
MKGRSALLRALWIAALSFGLGGVAVAAEPTAKAAPYENLMVPSPSMGRDIPVAFLAGGPHAVYLLDAFNAGPDVSNWVTAGNAMNTLAGKGISVVAPAGGAYSMYTNWEQDGSKQWDTFLSAELPDWLAANRGLAPGGHAAVGAAQGGYGAMALAAFHPDRFGFAGSMSGFLYPSNTTTNGAIAAGMQQFGGVDTNGMWGAPQLGRWKWHDPWVHASLLAQNNTRVWVWSPTNPGASDPAAMIGQAAEAMGNSRMFYNQYRSVGGHNGHFDFPASGDNGWGSWAPQLGAMSGDIVGAIR
- Mass
- 31,089 Da
- Length
- 299 Aa
Summary
Rv3803c doesn't seem to be a targeted by any drug.
Rv3803c doesn't seem to be involved in any pathway.
- The structure of Mycobacterium tuberculosis MPT51 (FbpC1) defines a new family of non-catalytic alpha/beta hydrolases.
- J Mol Biol. 2004 Jan 9;335(2):519-30.
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
- Mol Cell Proteomics. 2011 Dec;10(12):M111.011627. doi: 10.1074/mcp.M111.011445. Epub 2011 Oct 3.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.