pirG
- Type
- protein_coding
- Name
- pirG
- Locus Name
-
Rv3810
- Product
-
Exported repetitive protein precursor PirG (cell surface protein) (EXP53)
- Functional Category
-
None
- Location
- 4273739..4274593 (+ strand)
- Gene Length
- 854 bp
- Nucleotides
-
TGCCGAACCGACGCCGACGCAAGCTCTCGACAGCCATGAGCGCGGTCGCCGCCCTGGCAGTTGCAAGTCCTTGTGCATATTTTCTTGTCTACGAATCAACCGAAACGACCGAGCGGCCCGAGCACCATGAATTCAAGCAGGCGGCGGTGTTGACCGACCTGCCCGGCGAGCTGATGTCCGCGCTATCGCAGGGGTTGTCCCAGTTCGGGATCAACATACCGCCGGTGCCCAGCCTGACCGGGAGCGGCGATGCCAGCACGGGTCTAACCGGTCCTGGCCTGACTAGTCCGGGATTGACCAGCCCGGGATTGACCAGCCCGGGCCTCACCGACCCTGCCCTTACCAGTCCGGGCCTGACGCCAACCCTGCCCGGATCACTCGCCGCGCCCGGCACCACCCTGGCGCCAACGCCCGGCGTGGGGGCCAATCCGGCGCTCACCAACCCCGCGCTGACCAGCCCGACCGGGGCGACGCCGGGATTGACCAGCCCGACGGGTTTGGATCCCGCGCTGGGCGGCGCCAACGAAATCCCGATTACGACGCCGGTCGGATTGGATCCCGGGGCTGACGGCACCTATCCGATCCTCGGTGATCCAACACTGGGGACCATACCGAGCAGCCCCGCCACCACCTCCACCGGCGGCGGCGGTCTCGTCAACGACGTGATGCAGGTGGCCAACGAGTTGGGCGCCAGTCAGGCTATCGACCTGCTAAAAGGTGTGCTAATGCCGTCGATCATGCAGGCCGTCCAGAATGGCGGCGCGGCCGCGCCGGCAGCCAGCCCGCCGGTCCCGCCCATCCCCGCGGCCGCGGCGGTGCCACCGACGGACCCAATCACCGTGCCGGTCGCCTAA
- Drug Resistance
- Mutations
- Function
- Surface-exposed protein required for multiplication and intracellular growth.
- Family
-
Unknown
- GO
-
- growth of symbiont in host cell GO:0044119 biological_process
- pathogenesis GO:0009405 biological_process
- extracellular region GO:0005576 cellular_component
- plasma membrane GO:0005886 cellular_component
- integral component of membrane GO:0016021 cellular_component
- InterPro
Summary
- Name
- Exported repetitive protein (Cell surface protein PirG) (EXP53)
- Family
- Unknown
- Protein Sequence
-
MPNRRRRKLSTAMSAVAALAVASPCAYFLVYESTETTERPEHHEFKQAAVLTDLPGELMSALSQGLSQFGINIPPVPSLTGSGDASTGLTGPGLTSPGLTSPGLTSPGLTDPALTSPGLTPTLPGSLAAPGTTLAPTPGVGANPALTNPALTSPTGATPGLTSPTGLDPALGGANEIPITTPVGLDPGADGTYPILGDPTLGTIPSSPATTSTGGGGLVNDVMQVANELGASQAIDLLKGVLMPSIMQAVQNGGAAAPAASPPVPPIPAAAAVPPTDPITVPVA
- Mass
- 27,700 Da
- Length
- 284 Aa
Rv3810 doesn't seem to be a targeted by any drug.
Rv3810 doesn't seem to be involved in any pathway.
- Attenuation of virulence by disruption of the Mycobacterium tuberculosis erp gene.
- Science. 1998 Oct 23;282(5389):759-62. doi: 10.1126/science.282.5389.759.
- Identification of mycobacterium tuberculosis DNA sequences encoding exported proteins by using phoA gene fusions.
- J Bacteriol. 1995 Jan;177(1):59-65. doi: 10.1128/jb.177.1.59-65.1995.
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
- Nature. 1998 Jun 11;393(6685):537-44. doi: 10.1038/31159.
- Characterization of the Mycobacterium tuberculosis erp gene encoding a potential cell surface protein with repetitive structures.
- Microbiology. 1995 Sep;141 ( Pt 9):2123-30. doi: 10.1099/13500872-141-9-2123.